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Anwar Shahzad,Aastha Sahai 한국산림과학회 2014 Forest Science And Technology Vol.10 No.3
The present study reports variation in in vitro germination responses between two genotypes of Balanites aegyptiaca (L.)Del. an endangered agroforestry species. Fruits were collected from arid and semi-arid zones of Jodhpur (J) andAhmedabad (A) respectively. Mature seeds of both the germplasms were isolated and subjected to in vitro germination onMurashige and Skoog medium supplemented with gibberellic acid (GA). Marked differences were observed ingermination frequency of both genotypes at variable concentrations of GA. Whereas ‘A’ acquired 100% germinationfrequency on medium containing 1mM GA, ‘J’ required 2.5mM GA. Morphogenic variations for seedling traits were alsorecorded in relation to genotype for shoot, internode and root length along with number of nodes/shoot and leaf size andcolor. ‘A’ seedlings appeared healthy as compared to ‘J’ seedlings. These morphogenic variations were studied incorrelation with the native environmental conditions of both germplasms. In vitro germinated seedlings were hardened andacclimatized in ex situ conditions and survivability was checked during in vitro hardening and ex situ acclimatization inrelation to required humidity and shade density respectively.
Study of nanocrystalline ceria thin films deposited by e-beam technique
Anwar, M.S.,Kumar, Shalendra,Ahmed, Faheem,Arshi, Nishat,Seo, Yong Jun,Lee, Chan Gyu,Koo, Bon Heun Elsevier 2011 CURRENT APPLIED PHYSICS Vol.11 No.1
<P><B>Abstract</B></P><P>We have studied the effect of electron gun power and substrate temperature on the properties of nanocrystalline ceria thin films using electron beam evaporation method. The ceria films were grown on the glass substrate and characterized using different techniques such as: X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), Raman spectroscopy and UV-visible spectroscopy measurements. It was observed that electron gun power has influence on the crystallite size which increases (from 5 to 11 nm) as the gun power increases. Also, the crystallite size increases from 8 to 22 nm by increasing substrate temperature from room temperature (RT) to 400 °C. The FE-SEM images show that all the films have nanocrystalline growth. From the Raman spectra, we have observed two peaks at 466 and 565 cm<SUP>−1</SUP>. The peak at 466 cm<SUP>−1</SUP> is assigned to the presence of the F<SUB>2g</SUB> mode of CeO<SUB>2</SUB> whereas the peak at 565 cm<SUP>−1</SUP> is due to the presence of the oxygen vacancies. UV-visible measurements reflect that all the films have high transparency, more than 80% in the visible region.</P>
Caveolin-1 in Breast Cancer: Single Molecule Regulation of Multiple Key Signaling Pathways
Anwar, Sumadi Lukman,Wahyono, Artanto,Aryandono, Teguh,Haryono, Samuel J Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16
Caveolin-1 is a 22-kD trans-membrane protein enriched in particular plasma membrane invaginations known as caveolae. Cav-1 expression is often dysregulated in human breast cancers, being commonly upregulated in cancer cells and downregulated in stromal cells. As an intracellular scaffolding protein, Cav-1, is involved in several vital biological regulations including endocytosis, transcytosis, vesicular transport, and signaling pathways. Several pathways are modulated by Cav-1 including estrogen receptor, EGFR, Her2/neu, $TGF{\beta}$, and mTOR and represent as major drivers in mammary carcinogenesis. Expression and role of Cav-1 in breast carcinogenesis is highly variable depending on the stage of tumor development as well as context of the cell. However, recent data have shown that downregulation of Cav-1 expression in stromal breast tumors is associated with frequent relapse, resistance to therapy, and poor outcome. Modification of Cav-1 expression for translational cancer therapy is particularly challenging since numerous signaling pathways might be affected. This review focuses on present understanding of Cav-1 in breast carcinogenesis and its potential role as a new biomarker for predicting therapeutic response and prognosis as well as new target for therapeutic manipulation.
Preparation of Porous Carbons from Sugars and their Application for Carbon Capture
Anwar Md. Hossain,박서경,김훈식,이제승 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.4
Porous carbon materials derived from sugars have been prepared by a new method using silica aerogel as a template. The silica aerogels were prepared by the reaction of tetramethyl orthosilicate (TMOS) and formic acid in the presence of sugar (d-fructose, d-glucose, or sucrose). Prepared silica aerogels containing sugar were carbonized under inert atmosphere followed by the removal of silicate with KOH solution to obtain the porous carbon materials. Prepared porous carbons with smaller amount of TMOS show higher surface areas (up to 312.2 m2/g) than the carbons prepared sugars themselves without using TMOS (108.7–277.3 m2/g). However, the surface areas of porous carbons decreased dramatically at the weight ratios of TMOS/sugar over 0.25. By increasing the surface areas of porous carbons, CO2 adsorption capacities of porous carbon materials increased up to 3.73 mmol/g.
Screening of BRCA1/2 Mutations Using Direct Sequencing in Indonesian Familial Breast Cancer Cases
Anwar, Sumadi Lukman,Haryono, Samuel J,Aryandono, Teguh,Datasena, I Gusti Bagus Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Breast cancer has emerged as the most prevalent cancer among women worldwide, including in Indonesia. The contribution of genes associated with high-risk breast-ovarian cancers, BRCA1 and BRCA2, in the Indonesian population is relatively unknown. We have characterized family history of patients with moderate- to high-risk of breast cancer predisposition in 26 unrelated cases from Indonesia for BRCA1/2 mutation analyses using direct sequencing. Known deleterious mutations were not found in either BRCA1 or BRCA2 genes. Seven variants in BRCA2 were documented in 10 of 26 patients (38%). All variants were categorized as unclassified (VUSs). Two synonymous variants, c.3623A>G and c.4035T>C, were found in 5 patients. One variant, c4600T>C, was found in a 38 year old woman with a family history of breast cancer. We have found 4 novel variants in BRCA2 gene including c.6718C>G, c.3281A>G, c.10176C>G, and c4490T>C in 4 unrelated patients, all of them having a positive family history of breast cancer. In accordance to other studies in Asian population, our study showed more frequent variants in BRCA2 compared to BRCA1. Further studies involving larger numbers of hereditary breast cancer patients are required to reveal contribution of BRCA1/2 mutations and/or other predisposing genes among familial breast cancer patients in Indonesia.
An Energy Efficient Interference-aware Routing Protocol for Underwater WSNs
( Anwar Khan ),( Nadeem Javaid ),( Ihsan Ali ),( Mohammad Hossein Anisi ),( Atiq Ur Rahman ),( Naeem Bhatti ),( Muhammad Zia ),( Hasan Mahmood ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.10
Interference-aware routing protocol design for underwater wireless sensor networks (UWSNs) is one of the key strategies in reducing packet loss in the highly hostile underwater environment. The reduced interference causes efficient utilization of the limited battery power of the sensor nodes that, in consequence, prolongs the entire network lifetime. In this paper, we propose an energy-efficient interference-aware routing (EEIAR) protocol for UWSNs. A sender node selects the best relay node in its neighborhood with the lowest depth and the least number of neighbors. Combination of the two routing metrics ensures that data packets are forwarded along the least interference paths to reach the final destination. The proposed work is unique in that it does not require the full dimensional localization information of sensor nodes and the network total depth is segmented to identify source, relay and neighbor nodes. Simulation results reveal better performance of the scheme than the counterparts DBR and EEDBR techniques in terms of energy efficiency, packet delivery ratio and end-to-end delay.