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      • Beyond robust design : an example of synergy between statistics and advanced engineering design

        Barone, Stefano,Erto, Pasquale,Lanzotti, Antonio 한국품질경영학회 2002 The Asian Journal on Quality Vol.3 No.2

        Higher efficiency and effectiveness of Research & Development phases can be attained using advanced statistical methodologies. In this work statistical methodologies are combined with a deterministic approach to engineering design. In order to show the potentiality of such integration, a simple but effective example is presented. It concerns the problem of optimising the performances of a paper helicopter. The design of this simple device is not new in quality engineering literature and has been mainly used for educational purposes. Taking full advantage of fundamental engineering knowledge, an aerodynamic model is originally formulated in order to describe the flight of the helicopter. Screening experiments were necessary to get first estimates of model parameters. Subsequently, deterministic evaluations based on this model were necessary to set up further experimental phases needed to search for a better design. Thanks to this integration of statistical and deterministic phases, a significant performance improvement is obtained. Moreover, the engineering knowledge turns out to be developed since an explanation of the "why" of better performances, although approximate, is achieved. The final design solution is robust in a broader sense, being both validated by experimental evidence and closely examined by engineering knowledge.

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        Influence of implant mucosal thickness on early bone loss: a systematic review with meta-analysis

        Riccardo Di Gianfilippo,Nicola Alberto Valente,Paolo Toti,Hom-Lay Wang,Antonio Barone 대한치주과학회 2020 Journal of Periodontal & Implant Science Vol.50 No.4

        Purpose: Marginal bone loss (MBL) is an important clinical issue in implant therapy. One feature that has been cited as a contributing factor to this bone loss is peri-implant mucosal thickness. Therefore, in this report, we conducted a systematic review of the literature comparing bone remodeling around implants placed in areas with thick (≥2-mm) vs. thin (<2- mm) mucosa. Methods: A PICO question was defined. Manual and electronic searches were performed of the MEDLINE/PubMed and Cochrane Oral Health Group databases. The inclusion criteria were prospective studies that documented soft tissue thickness with direct intraoperative measurements and that included at least 1 year of follow-up. When possible, a meta-analysis was performed for both the overall and subgroup analyses. Results: Thirteen papers fulfilled the inclusion criteria. A meta-analysis of 7 randomized clinical trials was conducted. Significantly less bone loss was found around implants with thick mucosa than around those with thin mucosa (difference, −0.53 mm; P<0.0001). Subgroups were analyzed regarding the apico-coronal positioning, the use of platformmatched vs. platform-switched (PS) connections, and the use of cement-retained vs. screw-retained prostheses. In these analyses, thick mucosa was found to be associated with significantly less MBL than thin mucosa (P<0.0001). Among non-matching (PS) connections and screw-retained prostheses, bone levels were not affected by mucosal thickness. Conclusions: Soft tissue thickness was found to be correlated with MBL except in cases of PS connections used on implants with thin tissues and screw-retained prostheses. Mucosal thickness did not affect implant survival or the occurrence of biological or aesthetic complications.

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