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RISS 인기검색어
- 검색키워드
- 저자 : Anmar Hameed Bloh (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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Marked Change in Parameter Level in Patient with Renal Disease
Anmar Hameed Bloh,Dr. Antesar Rheem Obead,Doaa Nassr Wahhab 대한화학회 2022 대한화학회지 Vol.66 No.2
Failure Renal is the function of the kidneys to remove waste products and keep them on the periphery. and minerals for the body. Chronic renal failure is a syndrome characterized by a slow, irreversible deterioration of renal function due to the slow destruction of renal parenchyma. Calcium is one of the important minerals that the body contains in the blood and important tissues, and it has an important role in vital processes such as muscle contraction, nerve impulse conduction, the efficiency of heart muscle work, and blood clotting processes. The aim of the study is to study and compare calcium levels in men and women. It includes studying abnormal levels of calcium that cause many diseases, including chronic renal failure, and studying changes associated with renal failure. The method of this study was conducted on patients with chronic renal failure at Murjan Teaching Hospital in Babylon city during the period. The study included a sample of 70 patients (40 males, 30 females) with chronic renal failure, their ages ranged from 30-65, and 60 (30 males, 30 females) healthy without the disease of the same age. The result was a significant decrease in the number of red and white blood cells, hemoglobin concentration, hematocrit and platelets in patients with chronic renal failure, The result has been showed significant level in enzymes activity for transfer of amine group (alanine amino transferase, aspartate amino transferas) and phosphatase alkaline and also concentration of total bilirubin in patient with compare with healthy, Significantly increases, were found in the concentration of urea, uric acid and creatinine, as well as the concentration of calcium and phosphorous ions in the blood serum of patients compared to healthy controls.
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Characterization and expression of SabA and BabA genes in Helicobacter pylori under varying pH
Hamzah Abdulrahman Salman,Eman Mobder Nayif,Anmar Hameed Bloh 한국미생물학회 2021 미생물학회지 Vol. No.
Helicobacter pylori is a potential cause for peptic ulcers whichcan make persistent chronic infection. Helicobacter pylori produceurease at low pH to neutralize the acidic environment to colonizethe gastric mucosa. This investigation aimed to characterize H. pylori based on urease, adherence, motility, and biofilm activityand to determine the gene expression of SabA and BabA byreal-time qRT-PCR. The reference culture H. pylori ATCC49503 was employed in the current study. The characterization ofH. pylori, such as biofilm, urease, adherence, and motility assays,was determined in acidic environments with the supplement ofurea substrate. Real-time qRT-PCR was executed to find thepossible explanation for the colonization by the genes actin,SabA, and BabA. The study indicated that urea substrate isimportant in biofilm activity, adherence, motility, and urease ofH. pylori. Helicobacter pylori ATCC 49503 showed enhancedactivity at pH 2.5 only when supplemented with urea substrate. Real-time qRT-PCR confirmed the positive and significantexpression of the SabA and BabA genes in an acidic environmentand its cooperative role in biofilm and the motility of H. pylori. The results propose that urease within H. pylori is necessary toneutralize the acidic niche and colonize effectively within themucosal layers of the stomach. Additionally, the colonizationand adaptability of H. pylori in the in vitro were dependant onurease and pH. Further studies are proposed to understand thecolonization of clinical strains of H. pylori.
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