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Tripathi, Om P.,Baldwin, Mark,Charlton‐,Perez, Andrew,Charron, Martin,Eckermann, Stephen D.,Gerber, Edwin,Harrison, R. Giles,Jackson, David R.,Kim, Baek‐,Min,Kuroda, Yuhji,Lang, Andrea,Mah John WileySons, Ltd 2015 Quarterly journal of the Royal Meteorological Soci Vol.141 No.689
<P>Extreme variability of the winter‐ and spring‐time stratospheric polar vortex has been shown to affect extratropical tropospheric weather. Therefore, reducing stratospheric forecast error may be one way to improve the skill of tropospheric weather forecasts. In this review, the basis for this idea is examined. A range of studies of different stratospheric extreme vortex events shows that they can be skilfully forecasted beyond 5 days and into the sub‐seasonal range (0–30 days) in some cases. Separate studies show that typical errors in forecasting a stratospheric extreme vortex event can alter tropospheric forecast skill by 5–7% in the extratropics on sub‐seasonal time‐scales. Thus understanding what limits stratospheric predictability is of significant interest to operational forecasting centres. Both limitations in forecasting tropospheric planetary waves and stratospheric model biases have been shown to be important in this context.</P>
Tripathi, Om P.,Baldwin, Mark,Charlton-Perez, Andrew,Charron, Martin,Cheung, Jacob C. H.,Eckermann, Stephen D.,Gerber, Edwin,Jackson, David R.,Kuroda, Yuhji,Lang, Andrea AMERICAN METEOROLOGICAL SOCIETY 2016 Monthly weather review Vol.144 No.5
<P>The first multimodel study to estimate the predictability of a boreal sudden stratospheric warming (SSW) is performed using five NWP systems. During the 2012/13 boreal winter, anomalous upward propagating planetary wave activity was observed toward the end of December, which was followed by a rapid deceleration of the westerly circulation around 2 January 2013, and on 7 January 2013 the zonal-mean zonal wind at 608N and 10 hPa reversed to easterly. This stratospheric dynamical activity was followed by an equatorward shift of the tropospheric jet stream and by a high pressure anomaly over the North Atlantic, which resulted in severe cold conditions in the United Kingdom and northern Europe. In most of the five models, the SSW event was predicted 10 days in advance. However, only some ensemble members in most of the models predicted weakening of westerly wind when the models were initialized 15 days in advance of the SSW. Further dynamical analysis of the SSW shows that this event was characterized by the anomalous planetary wavenumber-1 amplification followed by the anomalous wavenumber-2 amplification in the stratosphere, which resulted in a split vortex occurring between 6 and 8 January 2013. The models have some success in reproducing wavenumber-1 activity when initialized 15 days in advance, but they generally failed to produce the wavenumber-2 activity during the final days of the event. Detailed analysis shows that models have reasonably good skill in forecasting tropospheric blocking features that stimulate wavenumber-2 amplification in the troposphere, but they have limited skill in reproducing wavenumber-2 amplification in the stratosphere.</P>
Cosmic CARNage I: on the calibration of galaxy formation models
Knebe, Alexander,Pearce, Frazer R,Gonzalez-Perez, Violeta,Thomas, Peter A,Benson, Andrew,Asquith, Rachel,Blaizot, Jeremy,Bower, Richard,Carretero, Jorge,Castander, Francisco J,Cattaneo, Andrea,Cora, S Oxford University Press 2018 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.475 No.3
<P>We present a comparison of nine galaxy formation models, eight semi-analytical, and one halo occupation distribution model, run on the same underlying cold dark matter simulation (cosmological box of comoving width 125h(-1) Mpc, with a dark-matter particle mass of 1.24 x 10(9) h(-1)M(circle dot)) and the same merger trees. While their free parameters have been calibrated to the same observational data sets using two approaches, they nevertheless retain some 'memory' of any previous calibration that served as the starting point (especially for the manually tuned models). For the first calibration, models reproduce the observed z = 0 galaxy stellar mass function (SMF) within 3 sigma The second calibration extended the observational data to include the z = 2 SMF alongside the z similar to 0 star formation rate function, cold gas mass, and the black hole bulge mass relation. Encapsulating the observed evolution of the SMF from z = 2 to 0 is found to be very hard within the context of the physics currently included in the models. We finally use our calibrated models to study the evolution of the stellar-to-halo mass (SHM) ratio. For all models, we find that the peak value of the SHM relation decreases with redshift. However, the trends seen for the evolution of the peak position as well as the mean scatter in the SHM relation are rather weak and strongly model dependent. Both the calibration data sets and model results are publicly available.</P>
Tommaso Giuliani,Maria Lopez Rubio,Eva Montalva Oron,Javier Maupoey Ibanez,Andrea Bosca Robledo,Cecilia Lopez Valdivia,Judith Perez Rojas,Rafael Lopez Andujar 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.1
Indications and outcomes of extended pancreatectomies have been recently appraised by the International Study Group for Pancreatic Surgery. However, no definitive conclusions have been drawn, particularly in the setting of neoadjuvant treatments. We present here a case of 53-year-old man diagnosed with a bulky adenocarcinoma of the tail of the pancreas and infiltrating the adjacent organs and the thoracic wall. The patient was sent to neoadjuvant chemotherapy and he underwent 12 cycles of FOLFIRINOX. Since a significant radiological response was observed after chemotherapy, the patient was scheduled for extended distal pancreatectomy with en bloc resection of the thoracic wall, in order to achieve a radical resection. The surgery is herein described with all technical details. The patient was discharged after an uneventful early post-operative course and subsequently readmitted for a late grade B post-operative pancreatic fistula, which was ultimately treated successfully. Pathology showed complete response. When performed in centers with ample experience in pancreatic surgery, extended pancreatic resections represent a viable curative option with acceptable surgical outcomes. In this setting, challenging tailored resections should be considered to achieve negative margins, particularly following maximized effective downstaging strategies.
Assessment of the anterior loop of the mandibular canal: A study using cone-beam computed tomography
Nascimento, Eduarda Helena Leandro do,Pontual, Maria Luiza dos Anjos,Pontual, Andrea dos Anjos,Perez, Danyel Elias da Cruz,Figueiroa, Jose Natal,Frazao, Marco Antonio Gomes,Ramos-Perez, Flavia Maria d Korean Academy of Oral and Maxillofacial Radiology 2016 Imaging Science in Dentistry Vol.46 No.2
Purpose: Sufficient area in the interforaminal region is required for dental implant placement, and the anterior loop of the mandibular canal is located within the limits of this area. The aim of this study was to evaluate the prevalence and extent of the anterior loop in a Brazilian sample population using cone-beam computed tomography (CBCT). Materials and Methods: CBCT images from 250 patients (500 hemimandibles) obtained for various clinical indications were randomly selected and evaluated to determine the presence and length of the anterior loop. The length of the anterior loop was then compared based on gender, age, and the side of the mandible. The data were analyzed using the Pearson chi-square test and linear regression analysis. Results: An anterior loop was identified in 41.6% of the cases, and its length ranged from 0.25 mm to 4.00 mm (mean, $1.1{\pm}0.8mm$). The loop had a greater mean length and was significantly more prevalent in males (p=0.014). No significant differences were found between the right and left sides regarding length (p=0.696) or prevalence (p=0.650). Conclusion: In this study, a high prevalence of the anterior loop of the mandibular canal was found, and although its length varied greatly, in most cases it was less than 1 mm long. Although this is a prevalent anatomical variation, safety limits for the placement of implants in this region cannot be established before an accurate evaluation using imaging techniques in order to identify and preserve the neurovascular bundles.
Ribas, Beatriz Ribeiro,Nascimento, Eduarda Helena Leandro,Freitas, Deborah Queiroz,Pontual, Andrea dos Anjos,Pontual, Maria Luiza dos Anjos,Perez, Danyel Elias Cruz,Ramos-Perez, Flavia Maria Moraes Korean Academy of Oral and Maxillofacial Radiology 2020 Imaging Science in Dentistry Vol.50 No.4
Purpose: The objective of the present study was to evaluate the prevalence of dental implants positioning errors and their associations with adjacent structures and anatomical variations by means of cone-beam computed tomography (CBCT). Materials and Methods: CBCT images of 207 patients (584 dental implants) were evaluated by 2 oral radiologists. The distance between the implant and the adjacent teeth/implants was measured and classified as adequate (≥1.5 mm and ≥3 mm, respectively) or inadequate. The presence of thread exposure, cortical perforation, implant dehiscence, implant penetration into adjacent structures, and anatomical variations was also recorded. The incisor canal diameter and the depth of the concavity of the submandibular fossa were measured in order to evaluate their correlations with the frequency of implant penetration in these structures. Descriptive analyses, the Fisher exact test, and Spearman correlation analysis were performed (α=0.05). Results: The overall prevalence of positioning errors was 82.9%. The most common error was the inadequate distance between the implant and the adjacent teeth/implants. The presence of anatomical variations did not significantly influence the overall prevalence of errors (P>0.05). There was a positive correlation between the diameter of the incisor canal and the frequency of implant penetration in this structure (r=0.232, P<0.05). Conclusion: There was a high prevalence of dental implant positioning errors, and positioning errors were not associated with the presence of anatomical variations. Professionals should be aware of the space available for implant placement during the preoperative planning stage.
Analysis of the transcripts encoding for antigenic proteins of Bovine Gammaherpesvirus 4
Florencia Romeo,Maximiliano J. Spetter,Pedro Moran,Susana Pereyra,Anselmo Odeon,Sandra E. Perez,Andrea E. Verna 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.1
The major glycoproteins of bovine gammaherpesvirus 4 (BoHV-4) are gB, gH, gM, gL, and gp180 with gB, gH, and gp180 being the most glycosylated. These glycoproteins participate in cell binding while some act as neutralization targets. Glycosylation of these envelope proteins may be involved in virion protection against neutralization by antibodies. In infected cattle, BoHV-4 induces an immune response characterized by low neutralizing antibody levels or an absence of such antibodies. Therefore, virus seroneutralization in vitro cannot always be easily demonstrated. The aim of this study was to evaluate the neutralizing capacity of 2 Argentine BoHV-4 strains and to associate those findings with the gene expression profiles of the major envelope glycoproteins. Expression of genes coding for the envelope glycoproteins occurred earlier in cells infected with isolate 10/154 than in cells infected with strain 07/435, demonstrating a distinct difference between the strains. Differences in serological response can be attributed to differences in the expression of antigenic proteins or to post-translational modifications that mask neutralizing epitopes. Strain 07/435 induced significantly high titers of neutralizing antibodies in several animal species in addition to bovines. The most relevant serological differences were observed in adult animals. This is the first comprehensive analysis of the expression kinetics of genes coding for BoHV-4 glycoproteins in 2 Argentine strains (genotypes 1 and 2). The results further elucidate the BoHV-4 life cycle and may also help determine the genetic variability of the strains circulating in Argentina.
Fontenele, Rocharles Cavalcante,Nascimento, Eduarda Helena Leandro,Imbelloni-Vasconcelos, Ana Catarina,Martins, Luciano Augusto Cano,Pontual, Andrea dos Anjos,Ramos-Perez, Flavia Maria Moraes,Freitas, Korean Academy of Oral and Maxillofacial Radiology 2022 Imaging Science in Dentistry Vol.52 No.-
Purpose: The aim of this study was to assess the influence of kilovoltage- peak (kVp) and the metal artifact reduction (MAR) tool on the detection of buccal and lingual peri-implant dehiscence in the presence of titanium-zirconia (Ti-Zr) and zirconia (Zr) implants in cone-beam computed tomography (CBCT) images. Materials and Methods: Twenty implant sites were created in the posterior region of human mandibles, including control sites (without dehiscence) and experimental sites (with dehiscence). Individually, a Ti-Zr or Zr implant was placed in each implant site. CBCT scans were performed using a Picasso Trio device, with variation in the kVp setting (70 or 90 kVp) and whether the MAR tool was used. Three oral radiologists scored the detection of dehiscence using a 5-point scale. The area under the receiver operating characteristic (ROC) curve, sensitivity, and specificity were calculated and compared by multi-way analysis of variance (α=0.05). Results: The kVp, cortical plate involved (buccal or lingual cortices), and MAR did not influence any diagnostic values (P>0.05). The material of the implant did not influence the ROC curve values(P>0.05). In contrast, the sensitivity and specificity were statistically significantly influenced by the implant material (P<0.05) with Zr implants showing higher sensitivity values and lower specificity values than Ti-Zr implants. Conclusion: The detection of peri-implant dehiscence was not influenced by kVp, use of the MAR tool, or the cortical plate. Greater sensitivity and lower specificity were shown for the detection of peri-implant dehiscence in the presence of a Zr implant.