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Jiang, Jun,Bai, Zi Long,Chen, Zhi Hui,He, Long,Zhang, David Wei,Zhang, Qing Hua,Shi, Jin An,Park, Min Hyuk,Scott, James F.,Hwang, Cheol Seong,Jiang, An Quan Nature Publishing Group, a division of Macmillan P 2018 NATURE MATERIALS Vol.17 No.1
Erasable conductive domain walls in insulating ferroelectric thin films can be used for non-destructive electrical read-out of the polarization states in ferroelectric memories. Still, the domain-wall currents extracted by these devices have not yet reached the intensity and stability required to drive read-out circuits operating at high speeds. This study demonstrated non-destructive read-out of digital data stored using specific domain-wall configurations in epitaxial BiFeO<SUB>3</SUB> thin films formed in mesa-geometry structures. Partially switched domains, which enable the formation of conductive walls during the read operation, spontaneously retract when the read voltage is removed, reducing the accumulation of mobile defects at the domain walls and potentially improving the device stability. Three-terminal memory devices produced 14 nA read currents at an operating voltage of 5 V, and operated up to T = 85 °C. The gap length can also be smaller than the film thickness, allowing the realization of ferroelectric memories with device dimensions far below 100 nm.
A Resistive Memory in Semiconducting BiFeO<sub>3</sub> Thin‐Film Capacitors
Jiang, An Quan,Wang, Can,Jin, Kui Juan,Liu, Xiao Bing,Scott, James F.,Hwang, Cheol Seong,Tang, Ting Ao,Lu, Hui Bin,Yang, Guo Zhen WILEY‐VCH Verlag 2011 ADVANCED MATERIALS Vol.23 No.10
<P><B>A ferroelectric‐resistive random access memory consisting of a conductive BiFeO<SUB>3</SUB></B> epitaxial thin film with a unipolar diode current modulated by electric polarization orientation is reported. This device has a memory that lasts for months, a sufficiently high on current and on/off ratio to permit ordinary sense amplifiers to measure “1” or “0”, and is fully compatible with complementary metal‐oxide semiconductor processing. </P>
MicroRNA-16 Inhibits Bladder Cancer Proliferation by Targeting Cyclin D1
Jiang, Qi-Quan,Liu, Bin,Yuan, Tao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7
MicroRNA-16 (miR-16) has been demonstrated to regulate proliferation and apoptosis in many types of cancers, but its biological function in bladder cancer remains unknown. Here, we found expression of miR-16 to be downregulated in bladder cancer in comparison with the adjacent normal tissues. Enforced expression of miR-16 was able to inhibit cell proliferation in TCHu-1 cells, in line with results for miR-16 antisense oligonucleotides (antisense miR-16). At the molecular level, our results further revealed that cyclin D1 expression was negatively regulated by miR-16. Therefore, the data reported here demonstrate that miR-16 is an important regulator in bladder cancer, which will contribute to better understanding of important mis-regulated miRNAs.
Sub‐Picosecond Processes of Ferroelectric Domain Switching from Field and Temperature Experiments
Jiang, An Quan,Lee, Hyun Ju,Hwang, Cheol Seong,Scott, James F. WILEY‐VCH Verlag 2012 Advanced Functional Materials Vol.22 No.1
<P><B>Abstract</B></P><P>After calculations of various domain‐switching current transients under the pulse from electrical circuit parameters, the field dependence of domain‐switching speeds is accurately estimated over five orders of magnitude in a wide temperature range of 5.4–280 K from the height of domain‐switching current in Pb(Zr<SUB>0.4</SUB>Ti<SUB>0.6</SUB>)O<SUB>3</SUB> thin films. These estimations are extended following Merz's equation [W. J. Merz, <I>Phys. Rev.</I> <B>1954</B>, <I><B>95</B></I>, 690] and an ultimate domain‐switching current density of 1.4 × 10<SUP>8</SUP> A cm<SUP>−1</SUP> is extracted at the highest field of 0.20 MV cm<SUP>−1</SUP>. From classical domain‐nucleation models with thermal fluctuations, an ultimate (asymptotic high‐field) nucleation time of 0.47 ps is derived when the domain sideways motion is kink‐nucleation‐rate limited.</P>
Jiang, Jin-Quan,Wang, Pu,Jiang, Li-Shuai,Zheng, Peng-Qiang,Feng, Fan Techno-Press 2018 Geomechanics & engineering Vol.14 No.4
The study of the mining effect influenced by a normal fault has great significance concerning the prediction and prevention of fault rock burst. According to the occurrence condition of a normal fault, the stress evolution of the working face and fault plane, the movement characteristics of overlying strata, and the law of fault slipping when the working face advances from footwall to hanging wall are studied utilizing UDEC numerical simulation. Then the inducing-mechanism of fault rock burst is revealed. Results show that in pre-mining, the in situ stress distribution of two fault walls in the fault-affected zone is notably different. When the working face mines in the footwall, the abutment stress distributes in a "double peak" pattern. The ratio of shear stress to normal stress and the fault slipping have the obvious spatial and temporal characteristics because they vary gradually from the higher layer to the lower one orderly. The variation of roof subsidence is in S-shape which includes slow deformation, violent slipping, deformation induced by the hanging wall strata rotation, and movement stability. The simulation results are verified via several engineering cases of fault rock burst. Moreover, it can provide a reference for prevention and control of rock burst in a fault-affected zone under similar conditions.
( Zhi Quan Jiang ) 중국어문연구회 2013 中國語文論叢 Vol.0 No.60
중국의 관료체제가 형성된 지 벌써 2000여년이 되었다. 당나라 때 과거제도를 실시한 이래에 중국은 점차 유교적 교육을 받아들이는 지식인을 위주로 한 관료사회와 관료 문화를 형성하였다. 관료적 언어와 어휘는 관료들의 교류 방식과 관료문화의 중요한 체제로서 중국 관료 문화의 일정한 특징을 체현해 내고 있다. 총체적으로 보면 관료적 언어와 어휘는 차별성을 갖추고 있으며, 감정적 색채가 농후하다. 자주 어휘의 본의를 왜곡하는가 하면 어휘의 내함과 외형을 바꾸기도 한다. 어기조사가 많고 어의가 정확하지 않아 모호하고 언어의 표현 형식이 경직되어 있으며, 전문술어와 학술술어를 상용하여 공식화 되어 있다. 또한 형식화가 심하여 상투어와 빈말이 많고 어휘의 감정적 효과를 중시하는 등의 특징을 가지고 있다. 이러한 관료적 어휘가 형성된 것은 관료 문화가 이루고 있는 기반과 맥을 같이 하는 것이고, 이는 모두 사회정치 체제와 역사문화의 영향에서 기인한 것이다. 또한 ‘5·4 신문화운동’이 비록 문언문을 없애기는 했지만 관료문화가 탄생한 문화적 기초인 봉건적 관료 중심의 문화는 철저한 비판과 개혁이 없었고, 또한 당시 중국의 특수한 당파 정치문화는 권력이 고도로 집중되어 있어서 민주적이면서도 감시·감독하는 정치 체제가 미비하여 특정 사람에게 의탁하는 정치체제를 가지고 있었기 때문이기도 하다. 관료적 언어어휘와 말투는 현대사회에서 상당한 부작용을 가지고 있다. 이는 업무 효율을 저하시키고 민중들의 불만을 불러일으키게 하며 사회가 조화롭고 안정되는 데에 이롭지 못한 영향을 끼치면서 인터넷, 신문, 텔레비전, 광고 등의 대중매체를 통해서 급속하게 기타 사회계층으로 확산되어 가고 있다. 관료어휘는 중국 정치 문화의 기본 특징들을 반영하고 있기 때문에 현재 보다 절실하게 개혁을 필요로 하는 언어체계이다.
Xiao-Quan Xu,Chen-Jiang Wu,Shan-Shan Lu,Qian-Qian Gao,Qing-Quan Zu,Xing-Long Liu,Hai-Bin Shi,Sheng Liu 대한영상의학회 2017 Korean Journal of Radiology Vol.18 No.5
Objective: To determine the relationship between intravoxel incoherent motion (IVIM) imaging derived quantitative metrics and serum soluble CD40 ligand (sCD40L) level in an embolic canine stroke model. Materials and Methods: A middle cerebral artery occlusion model was established in 24 beagle dogs. Experimental dogs were divided into low- and high-sCD40L group according to serum sCD40L level at 4.5 hours after establishing the model. IVIM imaging was scanned at 4.5 hours after model establishment using 10 b values ranging from 0 to 900 s/mm2. Quantitative metrics diffusion coefficient (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) of ischemic lesions were calculated. Quantitative metrics of ischemic lesions were normalized by contralateral hemisphere using the following formula: normalized D = Dstroke / Dcontralateral. Differences in IVIM metrics between the low- and high-sCD40L groups were compared using t test. Pearson’s correlation analyses were performed to determine the relationship between IVIM metrics and serum sCD40L level. Results: The high-sCD40L group showed significantly lower f and normalized f values than the low-sCD40L group (f, p < 0.001; normalized f, p < 0.001). There was no significant difference in D*, normalized D*, D, or normalized D value between the two groups (All p > 0.05). Both f and normalized f values were negatively correlated with serum sCD40L level (f, r = -0.789, p < 0.001; normalized f, r = -0.823, p < 0.001). However, serum sCD40L level had no significant correlation with D*, normalized D*, D, or normalized D (All p > 0.05). Conclusion: The f value derived from IVIM imaging was negatively correlated with serum sCD40L level. f value might serve as a potential imaging biomarker to assess the formation of microvascular thrombosis in hyperacute period of ischemic stroke.