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Jacqueline K. Lim,김태희,Paul E. Kilgore,Allison E. Aiello,최병민,이광철,유기환,송영환,김윤경 대한의학회 2014 Journal of Korean medical science Vol.29 No.4
There are limited data evaluating the relationship between influenza treatment andhospitalization duration. Our purpose assessed the association between differenttreatments and hospital stay among Korean pediatric influenza patients. Total 770 children≤ 15 yr-of-age hospitalized with community-acquired laboratory-confirmed influenza atthree large urban tertiary care hospitals were identified through a retrospective medicalchart review. Demographic, clinical, and cost data were extracted and a multivariablelinear regression model was used to assess the associations between influenza treatmenttypes and hospital stay. Overall, there were 81% of the patients hospitalized withlaboratory-confirmed influenza who received antibiotic monotherapy whereas only 4% ofthe patients received oseltamivir monotherapy. The mean treatment-related charges forhospitalizations treated with antibiotics, alone or with oseltamivir, were significantlyhigher than those treated with oseltamivir-only (P < 0.001). Influenza patients treatedwith antibiotics-only and antibiotics/oseltamivir combination therapy showed 44.9% and28.2%, respectively, longer duration of hospitalization compared to those treated withoseltamivir-only. Patients treated with antibiotics, alone or combined with oseltamivir,were associated with longer hospitalization and significantly higher medical charges,compared to patients treated with oseltamivir alone. In Korea, there is a need for morejudicious use of antibiotics, appropriate use of influenza rapid testing.
Lim, Jacqueline K.,Kim, Tae Hee,Kilgore, Paul E.,Aiello, Allison E.,Choi, Byung Min,Lee, Kwang Chul,Yoo, Kee Hwan,Song, Young-Hwan,Kim, Yun-Kyung The Korean Academy of Medical Sciences 2014 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.29 No.4
<P>There are limited data evaluating the relationship between influenza treatment and hospitalization duration. Our purpose assessed the association between different treatments and hospital stay among Korean pediatric influenza patients. Total 770 children 15 yr-of-age hospitalized with community-acquired laboratory-confirmed influenza at three large urban tertiary care hospitals were identified through a retrospective medical chart review. Demographic, clinical, and cost data were extracted and a multivariable linear regression model was used to assess the associations between influenza treatment types and hospital stay. Overall, there were 81% of the patients hospitalized with laboratory-confirmed influenza who received antibiotic monotherapy whereas only 4% of the patients received oseltamivir monotherapy. The mean treatment-related charges for hospitalizations treated with antibiotics, alone or with oseltamivir, were significantly higher than those treated with oseltamivir-only (P < 0.001). Influenza patients treated with antibiotics-only and antibiotics/oseltamivir combination therapy showed 44.9% and 28.2%, respectively, longer duration of hospitalization compared to those treated with oseltamivir-only. Patients treated with antibiotics, alone or combined with oseltamivir, were associated with longer hospitalization and significantly higher medical charges, compared to patients treated with oseltamivir alone. In Korea, there is a need for more judicious use of antibiotics, appropriate use of influenza rapid testing.</P>