動力噴霧機用 호오스에 關한 硏究

崔秉旻 順天大學校 1983 論文集 Vol.2 No.1

現在 動力噴霧機用으로 普及되어 있는 폴리비닐 호오스 4種과 市中에서 쉽게 구할 수 있는 비닐호오스 2種, 고무호오스 2種 및 高壓가스용 고무호오스 1種에 대해 호오스의 여러 性質및 使用可能性 與否를 調査하였는 바 그 結果를 綜合하면 다음과 같다. 1) 壓力의 增加에 따라 비닐호오스는 길이와 外徑이 同時에 增加하였고 一般고무호오스는 壓力의 增加에 따라 外徑이 增加하면서 길이는 減少하는 傾向을 보였으며 비닐호오스는 길이가 最高 8%, 外徑78%가 增加하였다. 2) 高壓가스용 고무호오스와 폴리비닐 호오스는 噴霧機壓力의 增加에 따라 外徑은 繼續 增加하였으며 길이는 어느 程度 減少하다 다시 增加하는 傾向을 보였는데 길이, 外徑의 伸縮率은 호오스 內外層의 材料와 特히 中間補强層의 材料가 큰 影響을 미쳤다. 3) 호오스 길이의 增加에 따른 壓力降下는 길이가 增加할수록 컸으며 같은 材質이라면 內徑이 적을수록 壓力降下量이 더 커졌다. 4) 動力噴霧機에서 노즐까지의 標高差에 의한 壓力變化는 1m에 0.1kg/㎠이었다. 5) 비닐材料와 고무材料의 引張强度와 破裂壓力은 比例하는 것으로 推定되며 고무材料에 比해 비닐材料가 引張强度가 크게 나타났다. 6) 現在 市販되고 있는 高壓用 고무호오스와 폴리비닐호오스는 壓力 35kg/㎠에서도 破裂되지 않으므로 動力噴霧機用 호오스로 使用이 可能하나 이밖의 비닐호오스와 고무호오스는 壓力 約10kg/㎠ 前後에서 破裂되기 때문에 使用이 不可能하다. In order to plan efficient controlling insects and diseases, it is necessary to use many power sprayers and much hose to bear up against high pressure simultaneously. The following are the summarized results obtained from an experiment about many properties and possibility of using for 4 kinds of polyvinyl hoses, 2 kinds of common vinyl hoses, 2 kinds of rubber hoses and a high pressure gas rubber hose. The results are as follows 1. The vinyl hoses showed an increase in the length and the outside diameter at the same time as the spraying pressure increases. Common rubber hoses showed an increase in the outside diameter and a decrease in the length. The maximum rate of change of the length of the vinyl hoses is 8% and the outside dimeter is nearly 78%. 2. The rubber hose for high pressure gas and the polyvinyl hoses showed an increase in the outside diameter, while it showed a decrease in the length up to a certain point at first time and showed an increase in the length. The rate of expansion of hoses was suffered by materials of the inside and the outside and expecially of the middle rein forcement bed. 3. The pressure loss was large by the length of hose increases, and if the same materials were used the pressure increase was large by the decrease of the inside diameter of hose. 4. The variation of pressure by height difference of a power sprayer to a nozzle was 0.1 kg/㎠ per 1m. 5. It was assumed that the degrees of tensile strength and the breakage pressure of vinyl and rubber is proportionate. The tensile strength of vinyl was larger than rubber. 6. The use of the rubber hose for high pressure gas and the polyvinyl hose is possible because they don't explode at the pressure of 35 kg/㎠. It is impossible to use the common rubber and vinyl hoses because they explode at the pressure of about 10kg/㎠.

국내 신생아 중환자실의 진료 현황과 향후 대책

최병민 한국모자보건학회 2018 한국모자보건학회 학술대회 연제집 Vol.2018 No.1

신생아에서 Indomethacin 투여가 신기능에 미치는 영향에 대한 연구

최병민,임애연,유기환,홍영숙,이주원 대한신장학회 1994 학술대회및초록집 Vol.13 No.2

신생 백서신장에서 안지오텐신 전환효소 억제가 MAPK Family 발현에 미치는 영향에 관한 연구

최병민,오미혜*,유기환 대한소아청소년과학회 2004 Clinical and Experimental Pediatrics (CEP) Vol.47 No.3

Purpose:In a developing kidney, the renin-angiotensin system(RAS) is markedly activated and is thought to play an important role in postnatal renal growth and maturation. We previously demonstrated that angiotensin converting enzyme(ACE) inhibition in a developing rat kidney increases apoptosis and decreases its related gene expressions, which may account for renal growth impairment. Among the mitogen-activated protein kinases(MAPK) family members, c-jun N terminal kinase(JNK) and p38 MAPK(p38) are thought to inhibit cell growth and induce apoptosis. This study was designed to investigate the relationship between the RAS and the MAPK family during neonatal renal development. Methods:Forty-nine neonatal Spargue-Dawley rats were separated into two groups. The enalapril group was treated with ACE inhibitor(enalapril:30 mg/kg/day) and the control group with normal saline for seven days. Their kidneys were removed for immunohistochemical stain and western blot analysis of JNK-2 and p38. Results:In the enalapril group, JNK-2 expression was strongly detected in the dilated cortical tubular epithelial cells, and JNK-2 protein expression was significantly increased compared to the control group. p38 expression was noted in the dilated tubular epithelial cells by ACE inhibitor and also p38 protein expression was significantly increased. Conclusion:These results suggest that the expressions of the MAPK family, especially JNK and p38, are modulated by ACE inhibition in the neonatal rat kidney. In regard of the correlation between MAPK activations and the occurrence of apoptosis in renal growth impairment by ACE inhibition, JNK and p38 may be implicated to participate in angiotensin II related intracellular signaling pathways of renal apoptosis in developing kidney. 목 적 : 레닌안지오텐신계(renin-angiotensin system, RAS)의 최종 산물인 안지오텐신 II(Ang II)는 인체에서 혈역학적 작용이외에도 여러 장기와 조직에서 중요한 성장인자로서 작용하고 있다. 저자들은 이미 신생 흰쥐에게 안지오텐신전환효소(angiotensin converting enzyme, ACE) 억제제를 주어 ANG II를 차단하였을 때 높은 사망률과 체중저하를 보였고 신장의 세포 증식이 감소하고 세포자멸사가 증가하는 것을 관찰한 바 있다. 본 연구에서는 신생 흰쥐에서 Ang II의 역할을 차단함으로서 야기되는 신장의 성장장애에서의 분자생물학적 신호전달경로를 알아보고자, 세포의 성장장애, 특히 세포자멸사와 관련된 MAPK로 알려진 c-Jun NH2-terminal kinase(JNK)와 p38 MAPK (p38)의 발현을 중심으로 관찰하였다.방 법 : 5마리의 임신 Sprague-Dawley 흰쥐에서 약 49마리의 신생 흰쥐를 취한 후 실험이 끝날 때까지 계속 같은 어미가 수유하도록 하였다. 생후 둘째 날부터 매일 1회 신생 흰쥐의 체중을 측정하고 Enalapril(Sigma Chemical Co., St. Louis, U.S.A.) 30 mg/kg을 경관을 통해 직접 위 내에 주입하고 Enalapril 군으로 분류하였다. 대조군은 생리 식염수 10 mL/kg을 같은 방법으로 위 내에 주입하였다. 7일간 위의 방법을 7회 반복한 후 생후 9일에 흰쥐를 희생시켜, 신장을 적출하였다. 통상적 방법에 의해 신장의 성장장애와 관련된 MAPK로 알려진 JNK-2와 p38의 발현을 면역조직화학 염색으로 확인하였고 웨스턴블롯 분석으로 JNK-2와 p38 단백질 발현을 측정하였다.

動力噴霧機用 호오스의 摩擦係數에 關한 硏究 : 內徑 13mm 폴리비닐호오스에 對하여 On the Polyvinyl Hose with Inside Diameter of 13mm

崔秉旻 順天大學校 1986 論文集 Vol.5 No.1

麾擦損失水頭 ?? 에 있어서 麾擦係數 ?? 이 本 實驗에 서 求한 實驗式이다. 그리고 이 實驗式은 淸水로 實驗하여 얻은 式이지만 如何한 液體의 農藥이라도 Re=vd/v를 求할 수 있으면 레이놀드의 比法側에 따라서 本 實驗式으로 f를 求할 수 있다. 그리고 폴리비닐호오스內의 壓力을 5㎏/㎠以下인 低壓의 範圍와 5∼25㎏/㎠사이의 高압의 境遇로 나누어 생각하면 低壓의 境遇에는 本 實驗式을 使用하는데 支障이 생기지 않으나 高壓에서는 먼저 f및 h를 求한 후 ?? , ?? 를 利用하여 ?? , ?? 를 求하면 된다. 여기서 ?? , ?? 는 實驗數値를 넣어서 計算하면 다음과 같이 된다. ?? ?? 로서 여기서 ?? 는 高壓으로 되어도 그 增加率이 僅少하기 때문에 ?? =1로 하여도 影響이 적겠지만 ?? 는 高壓으로 됨에 따라 減少率이 커지기 때문에 省略하는 것이 不可能하다. An experimental formula derived from this experiment is ?? in the friction gead loss. The equation of friction gead loss is( ?? ). According to the specific law of Reynolds, this experimental formula can obtainf. even though this experiment have been obtained from experiment with pure water, on the assumption that certain loquids of agricultural medicines can procure Reynolds' number( ?? ) The pressure in the polyvinyl hose is considered in the low pressure(under 5kg/cm²) and in the high pressure(among 5-25kg/cm²). In case of low pressure, this experimental formula is not an obstacle to experiment, but in case of high pressure, after f and h are obtained, f? and h? must be obtained from ?? , ?? . ?? and ?? calculated by an experimental value are as follows: ?? ?? Now ?? =1 has a little effect on this ecperiment beacuse ?? indicates a very small rate of increase according to be high pressure. But it is impossible that ?? is omitted in thes experiment, for ?? rises the rate of decrease according to be high pressure.

動力噴霧機用 폴리비닐호오스의 摩擦損失에 關한 實驗式

崔秉旻 順天大學校 1985 論文集 Vol.4 No.1

摩擦損失水頭 h=??에 있어서 λ=14.37 39??가 本 實驗에서 求한 實驗式이다. 그리고 이 實驗式은 淸水로 實驗하여 얻은 式이지만 始何한 液體의 農藥이라도 ??를 求할 수 있으면 레이놀드의 比法則에 따라서 本 實驗式으로 λ를 求할 수 있다. 그리고 폴리비닐호오스 內의 壓力을 5㎏/㎠以下인 低壓의 範圍와 5∼25㎏/㎠사이의 高壓의 境遇로 나누어 생각하면 低壓의 境遇에는 本 實驗式을 使用하는데 支障이 생기지 않으나 高壓에서는 먼저 λ 및 h를 求한후 ??=λ· ??=??라고 하여 ??, ??를 求하면 된다. 여기서 ?? ??에 實驗數値를 넣어서 計算하면 다음과 같이 된다. ??=?? ??=?? 인데 여기서 ??는 高壓으로 되어도 그 增加率이 僅少하기 때문에 ??=1로 하여도 영향이 적겠지만 ??는 高壓으로 됨에 따라 減少率이 커지기 때문에 省略하는 것이 不可能하다. I found the next formula on the coefficient of the frictional resistance of the polyvinyl hose(diameter10㎜)by my cxperiments. Let h=?? Then, I found λ=14.3739Re-0.59 However h=Head loss of the polyvinyl hose in some lenghth(m) ℓ=Some length of the polyvinyl hose(m) d=Inside diameter of the polyvinyl hose(m/s) v=Speed of a current in the polyvinyl hose(m/s) λ=Coefficient of the frictional resistance of the polyvinyl hose Re=Reynolds' number When we think about the influence of high pressures. ??p=??Cp hp=hxCpxRp However Cp=?? Rp=?? p=Given high pressure Omission is impossible at Rp, for the decrease ratio becomes larger at high pressure in this formula. But to set Cp=1 is hardly affected because the increase ratio is very small quantity.

한국인 집단의 분자유전학적 연구 : 7. 한국인 HPRT 효소에 대한 단일 클론 항체의 성상 7. CHARACTERIZATION OF MONOCLONAL ANTIBODIES TO HPRT

최병민,백상기,김영진 충남대학교부설 생명공학연구소 1991 생물공학연구지 Vol.1 No.-

Hypoxanthine-Guanine Phosphoribosyltransferase (HPRT; EC 2.4, 2.8) was isolated and purified to 2,161 fold from human erythrocytes. The molecular weight of purified HPRT was estimated by SDS-PAGE at 30,000. Polyclonal antisera against HPRT were prepared form guinea pig and mouse. By the indirect immunoprecipitation tests, Polyclonal antiserum from guinea pig showed 94.4% specific precipitation and mouse did 91.1%. With the hybridoma technique, the hybrid cell clones which were producing the monoclonal antibody against HPRT were made. And the excellent cell clones were also screened, hHT1 and hHT6, by the indirect immunoprecipitation test and enzyme immunoassay.

Nitric Oxide as a Pro-apoptotic as well as Anti-apoptotic Modulator

최병민,배현옥,장선일,김영명,정헌택 한국생화학분자생물학회 2002 BMB Reports Vol.35 No.1

상처치유시 Antisense TGF-β1 Oligodeoxynucleotides가 Inducible Nitric Oxide Synthase발현 조절에 미치는 영향

최병민,곽현정,전창덕,임정식,박석돈,정헌택 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.4

Wound healing in the skin may be complicated by both microbial invasion and inflammation. Following injury, platelet degranulation releases a number of chemotactic factors including transforming growth factor (TGF-fl) and platelet derived growth factor (PDGF). TGF-19 is a cytokines that modulates many cellular function and gene expression. However, it is not known whether TGF-P could regulate inducible nitric oxide synthase (iNOS) gene expression during wound healing. Here we report that down regulation of TGF-Q gene expression by antisense oligodeoxynucleotides increase iNOS during wound healing. Our reverse transcription- polymerase chain reaction (RT-PCR) result has shown that antisense TGF-fil oligodeoxynucleotides (ODN) targeting the TGF-J11 translation initiation region markedly reduced TGF-(il mRNA levels in wounded skin. Also, marked reduction in TGF-fl1 mRNA after antisense treatment invited that the increment of iNOS mRNA in wounded skin. Therefore, our irnmunohistochemical studies revealed a "pattern of iNOS product in wounded skin treated antisense TGF-fl1 ODN that was similar to the pattern of RNA synthesis detected by RT-PCR. In conclusion, our results indicated that the regulatory actions of TGF fl1 on iNOS. might be involved in the initiation and faciliates the resolution of inflammation following wounding.

인삼의 평형함수율에 관한 연구

최병민,이종호,박승제,김철수,이중용 ( B . M . Choi,J . H . Lee,S . J . Park,C . S . Kim,J . Y . Rhee ) 한국농업기계학회 1992 바이오시스템공학 Vol.17 No.3