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Second primary cancers in patients with urothelial cancers
Ali Feyzullah Şahin,Muammer Altok,Fırat Akdeniz,Güner Yıldız,Rauf Taner Divrik 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.5
Purpose: To investigate the second primary cancers (SPCs) in patients with urothelial cancer (UC). Materials and Methods: The records of 2,339 patients whose UC was diagnosed between January 1974 and December 2012 were reviewed. All data about characteristics of patients, of UC and, of SPC was, recorded digitally. We investigated the prevalence and the type of second or higher order cancers, and the factors associated with SPC. Results: Total 260 patients (11.1%) had SPC, 14 had a third primary cancer and one had a fourth primary cancer. The most common SPC with UC was lung cancer (29.6%). Of all 260 with SPC, 64 (24.6%) had synchronous (within the 6 months) SPC, 120 (46.2%) had subsequent SPC and, 76 (29.2%) had antecedent SPC. The mean duration of SPC was 56 months in patients with subsequent SPC and 75.8 months in patients with antecedent SPC. The mean age at the time of diagnosis of UC was higher in patients with SPC. The ratio of male gender, body mass index, blood type, status of smoking and, occupational risk was similar in both groups. Total amount of smoking and the mean follow-up were higher in patients with SPC. Conclusions: The majority of the patients with UC have long life expectancy. In patients with UC, the risk of having another cancer is quite higher than normal population. The physicians managing patients with UC should look for SPC.
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Properties and Corrosion Resistance of AISI H13 Hot-Work Tool Steel with Borided B4C Powders
Ali Günen,İsmail Hakki Karahan,Mustafa Serdar Karakaş,Bülent Kurt,Yusuf Kanca,Vedat Veli Çay,Murat Yıldız 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.9
In this study, the surface of AISI H13 steel was borided with powder blends of B4Cand NaBF4using the powder-pack methodat 800, 900 and 1000 °C for 2, 4 and 6 h. The structural and mechanical characteristics of the boride layers formed on thesurface were characterized using scanning electron microscopy, energy dispersive spectroscopy, X-ray diffractometry, 2Dsurface profilometry, microhardness and electrochemical corrosion (3.5 wt% NaCl) tests. The boride layer exhibited a singlephase structure (Fe2B) in samples coated at 800 °C and a dual-phase structure (FeB + Fe2B) at higher boriding temperatures(900 and 1000 °C). The boride layers were compact and crack-free in all boriding conditions. Depending on boridingparameters, the thickness, hardness and average surface roughness (Ra) of the coatings were found to range between 5.81and 102.46 μm, 1635–1915 HV and 0.315–0.650 μm, respectively. The borided AISI H13 steel displayed up to 33.5 timesand 2.4 times higher corrosion resistance than untreated AISI H13 steel and martensitic AISI 431 steel, respectively. Thissuggests potential use of borided AISI H13 steel in the steam turbines and marine applications as an alternative to the morecostly martensitic and duplex stainless steel grades. The corrosion resistance depended on the phase structure (single- ordual-layer), density, thickness and surface roughness of the boride coatings.
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A novel chaotic Runge Kutta optimization algorithm for solving constrained engineering problems
Yıldız Betül Sultan,Mehta Pranav,Panagant Natee,Mirjalili Seyedali,Yildiz Ali Riza 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.6
This study proposes a novel hybrid metaheuristic optimization algorithm named chaotic Runge Kutta optimization (CRUN). In this study, 10 diverse chaotic maps are being incorporated with the base Runge Kutta optimization (RUN) algorithm to improve their performance. An imperative analysis was conducted to check CRUN’s convergence proficiency, sustainability of critical constraints, and effectiveness. The proposed algorithm was tested on six well-known design engineering tasks, namely: gear train design, coupling with a bolted rim, pressure vessel design, Belleville spring, and vehicle brake-pedal optimization. The results demonstrate that CRUN is superior compared to state-of-the-art algorithms in the literature. So, in each case study, CRUN was superior to the rest of the algorithms and furnished the best-optimized parameters with the least deviation. In this study, 10 chaotic maps were enhanced with the base RUN algorithm. However, these chaotic maps improve the solution quality, prevent premature convergence, and yield the global optimized output. Accordingly, the proposed CRUN algorithm can also find superior aspects in various spectrums of managerial implications such as supply chain management, business models, fuzzy circuits, and management models.
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Cu and Mn centered nicotinamide/nicotinic acid complexes for interlayer of Schottky photodiode
Kocyigit Adem,Yıldız Dilber Esra,Hussaini Ali Akbar,Kose Dursun Ali,Yıldırım Murat 한국물리학회 2023 Current Applied Physics Vol.45 No.-
Schottky type photodiodes have gained great interest due to their fast response to light. Various materials have been used to improve their efficiency behaviors as interlayers or electrodes. In this study, we synthesized Cu- and Mn-centered nicotinamide/nicotinic acid complexes and used them for Schottky type photodiode as interfacial layer. Thus, Al/Cu-complex/p-Si and Al/Mn-complex/p-Si metal semiconductor heterojunctions were fabricated by Al metal and p-Si semiconductor. The I–V and I-t analyses were employed to identify the fabricated devices under various light power intensities. The devices were evaluated according to various diode parameters such as series resistance, ideality factor and barrier height values obtained by I–V characteristics data from thermionic emission theory, Cheung and Norde techniques. Furthermore, various parameters of photodetection such as specific detectivity, photosensitivity and responsivity were calculated from the I-t measurements. The results reveal that heterojunctions can be employed for photodiode applications.
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Predictive factors affecting morcellation efficiency in holmium laser enucleation of the prostate
Hakan Anıl,Ahmet Güzel,Ali Yıldız,Serkan Akdemir,Kaan Karamık,Murat Arslan 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.4
Purpose: To determine the factors affecting morcellation efficiency in holmium laser enucleation of the prostate (HoLEP) surgery. Materials and Methods: Patients who underwent HoLEP surgery by a single surgeon between 2018 and 2022 were included in the study. Our primary outcome of interest in this study was morcellation efficiency. The effect of preoperative and perioperative variables on morcellation efficiency was evaluated with linear regression analysis. Results: A total of 410 patients were included in the study. The mean morcellation efficiency was 6.95±1.70 g/min. Univariable and multivariable linear regression analysis was performed to identify factors affecting morcellation efficiency. Presence of the “beach ball” effect (small, round prostatic tissue fragments that are fibrotic and difficult to morcellate), the learning curve, resectoscope sheath type, prostate-specific antigen (PSA) density, morcellated tissue weight, and the presence of prostate calcification were found to be independent predictive factors (β=-1.107, 95% CI: -1.59 to -0.55, p<0.001; β=-0.514, 95% CI: -0.85 to -0.17, p=0.003; β=-0.394, 95% CI: -0.65 to -0.13, p=0.003; β=-0.302, 95% CI: -0.59 to -0.09, p=0.043; β=0.062, 95% CI: 0.05 to 0.06, p<0.001; β=-0.329, 95% CI: -0.55 to -0.10, p=0.004; respectively). Conclusions: This study reports that presence of the beach ball effect, the learning curve, small resectoscope sheath, PSA density, and presence of prostate calcification negatively affect morcellation efficiency. On the contrary, morcellated tissue weight has a linear relationship with morcellation efficiency.
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