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RISS 인기검색어
- 검색키워드
- 저자 : Ali M. Al-Amri (검색결과 2 건)
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Surgical management of thyroid tumor
Ali M. Al-Amri 대한종양외과학회 2014 Korean Journal of Clinical Oncology Vol.10 No.2
Purpose: To review the pattern of thyroid tumor, demographic data of the patients, sensitivity, and specificity of fine needle aspiration cytology. Methods: This is a retrospective analysis of patients who underwent total or near-total thyroidectomy at King Fahad Hospital of the University between 1982 and 2008. Data were analyzed for demographic characteristics, type of thyroid tumors, fine needle aspirations cytology (FNAC) yields and surgical complications. Results: A total of 143 patients with thyroid tumors underwent throidectomy. Their median age was 37.5 years. Females were predominantly affected (81%) with female to male ratio of (4.29:1). Thyroid carcinoma accounted for (75%) while benign tumors for (25%). The most common thyroid epithelial cancer was papillary type (74%) and was limited to thyroid tissues in almost two third of cases. Non-epithelial cancer in the form of thyroid lymphoma accounted for (4.89%) of the cases. FNAC sensitivity was 56% and specificity 92%. Surgical complications occurred in 18% of the patients. Conclusion: The commonest malignant thyroid cancer was papillary carcinoma. Thyroid cancer was more common in females. FNAC is highly accurate to confirm thyroid cancer but less sensitive in this study. Surgical complications were relatively minimal.
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Ibrahiem Saeed-Abdul-Rahman,Ali M. Al-Amri 대한혈액학회 2012 Blood Research Vol.47 No.3
Castleman and Towne described a disease presenting as a mediastinal mass resembling thymoma. It is also known as “giant lymph node hyperplasia”, “lymph node hamartoma”, “angiofollicular mediastinal lymph node hyperplasia”, and “angiomatous lymphoid hyperplasia”. The pathogenesis is unknown, but the bulk of evidence points toward faulty immune regulation, resulting in excessive B-lymphocyte and plasma-cell proliferation in lymphatic tissue. In addition to the mediastinal presentation, extrathoracic involvement in the neck, axilla, mesentery, pelvis, pancreas, adrenal gland, and retroperitoneum also have been described. There are 2 major pathologic variations of Castleman disease: (1) hyaline-vascular variant, the most frequent, characterized by small hyaline-vascular follicles and capillary proliferation; and (2) the plasma-cell variant, in which large lymphoid follicles are separated by sheets of plasma cells. The hyaline-vascular cases usually are largely asymptomatic, whereas the less common plasma-cell variant may present with fever, anemia, weight loss, and night sweats, along with polyclonal hypergamma-globulinemia. Castleman disease is a rare lymphoproliferative disorders. Few cases have been described world widely. In this article we reviewed the classification, pathogenesis, pathology, radiological features and up to date treatment with special emphasis on the role of viral stimulation, recent therapeutic modalities and the HIV-associated disease.
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