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      • KCI등재

        Arterial Compliance and Vitamin E Blood Levels with a Self Emulsifying Preparation of Tocotrienol Rich Vitamin E

        Aida Hanum Ghulam Rasool,Abd. Rashid Abd. Rahman,Kah Hay Yuen,Abdul Rahim Wong 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.9

        The tocotrienol vitamin E has potent antioxidant property, however absorption is low due to high lipid solubility. A self emulsifying preparation of tocotrienol rich vitamin E (SF-TRE) had been reported to increase their bioavailability. This randomized, placebo controlled, blinded end point clinical study aimed to determine the effects of 50, 100 and 200 mg daily of SF-TRE and placebo for two months on arterial compliance and vitamin E blood levels. Assessment of arterial compliance by carotid femoral pulse wave velocity (PWV) and augmentation index (AI), plasma vitamin E, serum total cholesterol and low density lipoprotein cholesterol were taken before and after 2 months’ treatment in 36 healthy males. Un-supplemented tocotrienol levels were low, after treatment, all SF-TRE treated groups had significantly higher plasma α, δ and δ tocotrienol concentrations compared to placebo. Augmentation index change from baseline to end of treatment for groups placebo, 50, 100, and 200 mg were 2.22±1.54, -6.59±2.84, -8.72±3.77, and -6.27±2.67% respectively (p=0.049, 0.049, and 0.047 respectively). Groups 100 and 200 mg showed significant improvement after treatment with pulse wave velocity reductions of 0.77 m/s and 0.65 m/s respectively (p=0.007 and p=0.002). There was no effect of SF-TRE on serum lipids. We conclude that there was a trend towards improvement in arterial compliance with 2 months’ of SF-TRE.

      • KCI등재

        The Relationship between Serum Vitamin C and Uric Acid Levels, Antioxidant Status and Coronary Artery Disease: a Case-Control Study

        ( Aida Torkzaban ),( Amirmansour Alavi Naeini ),( Akbar Hassanzadeh ),( Mehrdad Namdari ) 한국임상영양학회 2020 Clinical Nutrition Research Vol.9 No.4

        Coronary artery disease (CAD) is among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are affecting factors in the progress of atherosclerosis. The aim of this study was to measure serum levels of uric acid (UA) and vitamin C as well as the antioxidant status in patients with CAD, and compared them with those in healthy individuals. The present case-control study was performed on 44 cases and 44 controls. Demographic data and anthropometric indices were measured. The Food Frequency Questionnaire (FFQ) and International Physical Activity Questionnaire (IPAQ) were completed. After 12 hours of fasting,10 mL blood was sampled from the participants. Serum levels of UA, vitamin C, Total Antioxidant Capacity (TAC) and Malondialdehyde (MDA) were also measured. The data were finally analyzed by SPSS v22. A significant difference was observed between the groups in terms of UA and vitamin C. However, mean levels of MDA and TAC were not significantly different between groups. The differences between groups in terms of vitamin A, vitamin E, beta-carotene, zinc and selenium intakes were not significant either. A significant difference was detected between the groups in terms of vitamin C intake. Our results suggest that increase in UA and decrease in vitamin C in serum levels can be considered as risk factors for CAD patients. Due to a lack of any significant correlation between TAC and CAD risk in this study, further study with bigger sample size is needed.

      • KCI등재

        Comparison of the Effects of Four Cooking Methods on Fatty Acid Profiles and Nutritional Composition of Red Mullet (Mullus barbatus) Muscle

        Aida Koubaa,Nourhène Boudhrioua Mihoubi,Abdelwaheb Abdelmouleh,Abderrahmen Bouain 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.5

        This study was performed to examine the effects of different cooking methods (frying, steaming, oven cooking, and microwave cooking) on proximate chemical composition, mineral contents, and fatty acids profiles of red mullet (Mullus barbatus) fillets. The frying process caused a significant increase in fat content (from 13.37±0.04 to 34.44±0.20 g/100 g d.w.) and reduced the proportion of the palmitic acid of 50.73% and saturated fatty acids of 56.9%. While, the proportion of polyunsaturated fatty acids (PUFA) increased from 4.04% of total fatty acids for raw fillet to 49.17% of total fatty acids for fried fillets. The steamed, oven-cooked, and microwave-cooked fillets showed the best proportion of fat content, PUFA, and ω-6/ω-3 ratio as compared with fried red mullet fillets. Na, Mg,and Zn contents of cooked fish fillets significantly decreased.

      • Microflow Photochemistry - Acetone sensitized Addition of Isopropanol to (5R)-5-Menthyloxy-2-(5H)-furanone

        Aida, Shin,Nishiyama, Yasuhiro,Kakiuchi, Kiyomi,Hoffmann, Norbert,Fon, Adeline,Oelgemoller, Michael Korean Society of Photoscience 2013 Rapid communication in photoscience Vol.2 No.3

        Acetone sensitized photoadditions of isopropanol to (5R)-5-menthyloxy-2-(5H)-furanone were investigated in two different microflow reactor systems. Setup A employed a commercially available glass reactor under a UVB-panel. Setup B utilized a FEP microcapillary wrapped tightly around a Pyrex cylinder with a single UVB fluorescent tube at its center. The reactions under flow conditions were subsequently compared to analogue reactions conducted in a batch chamber reactor. Overall, the microflow systems gave faster conversions and higher isolated yields. The flexible microcapillary setup, however, showed the best performance and promise in terms of future scale-up and reactor optimization.

      • KCI등재

        Factors Influencing InformationSystemsAdoption: A Review of the Literature

        Aida Hakemi,Maslin Masrom 한국인터넷방송통신학회 2019 International Journal of Internet, Broadcasting an Vol.11 No.2

        For the last two decades, a number of information systems are developed for various aims, depending on business’ needs. There are a lot of organizations in the world which are using information systems in their environment, such as telecommunications organizations,universitiesand banks. Using informationsystemhas become crucial for most oforganizations regarding withincreasing the performance of work procedures and improve productivity and efficiency in general. There are many different models that have been designed and validated to explain the effect of constructs on the adoption of technologies. The aim of this research is to review the literature on information systems adoption and to analyze the different types of models which are frequently applied by researchers in their efforts to examine the factors that estimate the adoption of technologies. The research explores information systems adoption literature that focuses on development models.

      • KCI등재
      • KCI등재

        Effect of Rutin on Diabetic Auditory Neuropathy in an Experimental Rat Model

        Aida Doostkam,Hossein Mirkhani,Kamyar Iravani,Saied Karbalay-Doust,Kazem Zarei 대한이비인후과학회 2021 Clinical and Experimental Otorhinolaryngology Vol.14 No.3

        Objectives. Diabetic auditory neuropathy is a common complication of diabetes mellitus that has a major impact on patients’ quality of life. In this study, we assessed the efficacy of rutin in treating diabetic auditory neuropathy in an experimental rat model. Methods. Forty Sprague-Dawley rats were randomly assigned to the following groups: group 1, control; group 2, diabetic rats; and groups 3–5, rats treated with rutin (at doses of 50, 100, and 150 mg/kg, respectively). We used auditory brain stem response, stereology of the spiral ganglion, and measurements of superoxide dismutase (SOD) and malondialdehyde (MDA) to evaluate the effects of treatment. Results. Significant improvements in auditory neuropathy were observed in the rutin-treated groups in comparison with the diabetic group (P<0.05). Auditory threshold, wave latency, wave morphology, the volume and number of neurons in the spiral ganglion, and SOD and MDA activity showed improvements following treatment. Conclusion. Rutin shows promise as a treatment modality for diabetic auditory neuropathy, but more trials are warranted for its clinical application.

      • Poster Session : PS 0727 ; Rheumatology ; Sudden Sensorineural Hearing Loss and Microangiopathic Antiphospholipid Syndrome (MAPS)

        ( Aida Galicia ),( Juan Carlos Anda ),( Maximiliano Garcia ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        A 54-years-old man with history of acute pancreatitis 4 years before and secondary DM, he also had history of primary hypothyroidism and hypertension. He was admitted in hospital in 2010 with sudden and bilateral hearing loss, headache and dizziness. Neuro-otological examination revealed a sensorineural hearing loss (SNHL) and he was given Dexamethasone trans-tympanic, then he was treated with Ganciclovir (12 mg/kg/24 h) for 10 days + prednisone 50 mg/24 h for 4 weeks. At the end, pure tone audiometry confi rmed a SNHL affecting both ears. aCL antibodies were positives and he was send to internal medicine consultation. The diagnosis of microangiopathic antiphospholipid sindrome (MAPS) on the basis of presumed thrombotic cause of SNHL was made and he was formally anticoagulated with warfarin. He has had no additional thrombotic episodes, although SNHL prevails. Full blood count, serum electrolytes, renal function, urinalysis and cerebrospinal fi uid analysis were normal. Coagulation: PT 53. 1”, aPTT 92. 6”, Lupus anticoagulant: 1. 69 (positive<1. 2). Anti-ß2 Gp1 IgM:3350 (negative<8 U/ml), Anti-ß2 Gp1 IgG: 6. 8 (negative<14. 3 U/ml), aCL IgM: >255 (negative<15), aCL IgG: 46. 3 (negative<20). ANAs, Anti-dsDNA, Anti-Sm were negative. MRI of brain on T2 weighted showed white matter hyperintensities and subcortical hyperintensities in frontal and parietal lobes, meaning microangiopathic injury on brain parenchymal. Conclusion: MAPS is a subset of Antiphospholipid Syndrome which occlusive thrombosis of small blood vessels and microangiophaty dominate the clinical picture. Several neurological disorders have been described in association with antiphospholipid antibodies (aPL) without thrombosis of large-vessels like Myelitis Transverse, Multiple Sclerosis-like Disease, Dementia, Chorea, Migraine and Epilepsy. SNHL is a rare syndromethat leads rapidly progressive bilateral hearing loss, and it has been strongly associated with aPL. There are a few cases in medical literature and there is no consensus about appropriate treatment but anticoagulation is widely accepted.

      • KCI등재

        The effect of fuel type and calcination temperature on the structure and morphology of fabricated nano-cordierite based on gel-combustion method

        Aida Rahmani,Arman Sedghi 한양대학교 세라믹연구소 2016 Journal of Ceramic Processing Research Vol.17 No.10

        The aim of this study is to evaluate the influence of fuel type and temperature on the synthesis of nano-cordierite powder bygel combustion method. Two different fuels, urea and citric acid, along with silica fume and metal nitrates, as an oxidant, areused to prepare nano-cordierite powder. Ignited samples are calcinated in different temperatures and characterized bydifferent analytical techniques such as thermal analysis (TG-DTA), X-ray Diffractometer (XRD), Fourier transform infraredspectroscopy (FTIR) and field emission electron microscope (FE-SEM). The Debye-Scherer formula is used to calculate theaverage crystallite size. Although Analysis of XRD spectrum shows that α–cordierite nano-crystalline phase is formedcompletely, a minor spinel impurity phase is found in the structure. The average crystallite sizes calculated by FWHM areabout 47 to 87 nm. Morphology of powders are identified by FESEM analysis. While the results of implemented method showthat the particle size of powders is in nano-meter range, most of them are agglomerated.

      • KCI등재

        Enhancement of VECTOR Method by Adapting OCTAVE for Risk Analysis in Legacy System Migration

        ( Aida Hakemi ),( Seung Ryul Jeong ),( Imran Ghani ),( Mojtaba Ghanaatpisheh Sanaei ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.6

        Risks are involved in all phases of the software life cycle, and due to these risks, software can face various problems that can cause different negative outcomes and sometimes, in extreme cases, the failure of the software. Most of these risks lie in the legacy software migration process. These risks can create many problems, and in the worst case they can lead to the failure of the migration project. This paper explores different types of risk analysis methods such as CRAMM, CORAS, OCTAVE and VECTOR. After comparing these methods, the two suitable methods were chosen, namely, OCTAVE and VECTOR. Based on the use of these two methods, the project suggests an enhanced EOV method for risk analysis in the migration of legacy software.

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