http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
보건관리 대행사업장 근로자에서 건강증진에 대한 5년 사이의 지식, 태도 및 실천의 변화
임현우,김정아,안병용,박정일,구정완,이강숙 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2
Before and after conducting the health promotion program by group occupational health service during 5 years, we surveyed knowledge, attitude and practice about general health (30 items) and occupational health(30 items) among 25 small and medium scale industry workers(before: 355 workers, after: 279 workers) for evaluation of effectiveness. The scores of knowledge for smoking, drinking, cholesterol, mental stress, management of hypertension, and risks in younger or women workers were significantly increased after conducting group occupational health service. The scores of attitude for controlling of fatty food consumption and cleaning workplace and bathing for health and that of practice for taking the periodic health examination and checking blood pressure were significantly increased but most of items in attitude and practice didn't be changed after services. According to sex, the scores of men were significantly increased in knowledge of general health, but there were not significant differences in age, job status and work duration group. In conclusion, through the group occupational health service during 5 years, only the scores of knowledge in general health were increased. It suggested that the effective program which can change workers' attitude and practice for health promotion, should be developed and conducted in small and medium scale industry workers.
모 컴퓨터 회사 근로자 건강증진 사업 전개를 위한 수요조사
임현우,안병용,최환석,박정일,김경수,이강숙,김정아,구정완 가톨릭대학산업의학쎈타 산업의학연구소 1997 韓國의 産業醫學 Vol.36 No.4
Before conducting the health promotion program, we surveyed the health risk appraisal(HRA) of 210 workers (186 men and 24 women) in a computer company, for the need assessment, selection of target population, priority setting, and as a standard for comparision after performing the program. The smokers were 115(88.6%), and drinkers (over 1 bottle of Soju per week) were 91(44.8%) in men. Entire women and 148(78.0%) men never or irregularly exercise. Type A personality were 73(39.2%) in men, 8(33.3%) in women, and 26(14.0%) of men and 6(25.0%) of women were high stress risk group. 53(25.2%) of men and 2(8.3%) of women were obese (BMI ≥25kg/m²), and workers who consumed exess of total calory compared with recommendation were 142(76.3%) in men and 18(75%) of women. By the health risk appraisal, it was suggested that smoking cessation program, drinking counselling, exercise prescription, stress management, and weight control program should be conducted effectively for the high risk group.
Ahn, Ji Hyeon,Choi, Jung Hoon,Park, Joon Ha,Kim, In Hye,Cho, Jeong-Hwi,Lee, Jae-Chul,Koo, Hyun-Mo,Hwangbo, Gak,Yoo, Ki-Yeon,Lee, Choong Hyun,Hwang, In Koo,Cho, Jun Hwi,Choi, Soo Young,Kwon, Young-Guen SAGE Publications 2016 Neurorehabilitation and neural repair Vol.30 No.9
<P>Background. The positive correlation between therapeutic exercise and memory recovery in cases of ischemia has been extensively studied; however, long-term exercise begun after ischemic neuronal death as a chronic neurorestorative strategy has not yet been thoroughly examined. Objective. The purpose of this study is to investigate possible mechanisms by which exercise ameliorates ischemia-induced memory impairment in the aged gerbil hippocampus after transient cerebral ischemia. Methods. Treadmill exercise was begun 5 days after ischemia-reperfusion (I-R) and lasted for 1 or 4 weeks. The animals were sacrificed 31 days after the induction of ischemia. Changes in short-term memory, as well as the hippocampal expression of markers of cell proliferation, neuroblast differentiation, neurogenesis, myelin and microvessel repair, and growth factors were examined by immunohistochemistry and/or western blots. Results. Four weeks of exercise facilitated memory recovery despite neuronal damage in the stratum pyramidale (SP) of the hippocampal CA1 region and in the polymorphic layer (PoL) of the dentate gyrus (DG) after I-R. Long-term exercise enhanced cell proliferation and neuroblast differentiation in a time-dependent manner, and newly generated mature cells were found in the granule cell layer of the DG, but not in the SP of the CA1 region or in the PoL of the DG. In addition, long-term exercise ameliorated ischemia-induced damage of myelin and microvessels, which was correlated with increased BDNF expression in the CA1 region and the DG. Conclusions. These results suggest that long-term treadmill exercise after I-R can restore memory function through replacement of multiple damaged structures in the ischemic aged hippocampus.</P>
Increased immunoreactivity of c???Fos in the spinal cord of the aged mouse and dog.
Ahn, Ji Hyeon,Shin, Myoung Chul,Park, Joon Ha,Kim, In Hye,Lee, Jae-Chul,Yan, Bing Chun,Hwang, In Koo,Moon, Seung Myung,Ahn, Ji Yun,Ohk, Taek Geun,Lee, Tae Hun,Cho, Jun Hwi,Shin, Hyung-Cheul,Won, Moo-H SPANDIDOS PUBLICATIONS 2015 MOLECULAR MEDICINE REPORTS Vol.11 No.2
<P>Expression of c-Fos in the spinal cord following nociceptive stimulation is considered to be a neurotoxic biomarker. In the present study, the immunoreactivity of c-Fos in the spinal cord was compared between young adult (2-3 years in dogs and 6 months in mice) and aged (10-12 years in dogs and 24 months in mice) Beagle dogs and C57BL/6J mice. In addition, changes to neuronal distribution and damage to the spinal cord were also investigated. There were no significant differences in neuronal loss or degeneration of the spinal neurons observed in either the aged dogs or mice. Weak c-Fos immunoreactivity was observed in the spinal neurons of the young adult animals; however, c-Fos immunoreactivity was markedly increased in the nuclei of spinal neurons in the aged dogs and mice, as compared with that of the young adults. In conclusion, c-Fos immunoreactivity was significantly increased without any accompanying neuronal loss in the aged spinal cord of mice and dogs, as compared with the spinal cords of the young adult animals.</P>
Ahn, Ji Hyeon,Park, Joon Ha,Yan, Bing Chun,Lee, Jae-Chul,Choi, Jung Hoon,Lee, Choong Hyun,Yoo, Ki-Yeon,Hwang, In Koo,Kim, Jin Sang,Shin, Hyung-Cheul,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2013 Cellular and molecular neurobiology Vol.33 No.1
<P>Alpha-synuclein (α-syn), as a neuroprotein, is expressed in neural tissue, and it is related to a synaptic transmission and neuronal plasticity. In this study, we compared the distribution and immunoreactivity of α-syn and related gliosis in hippocampus between young adult (2-3?years) and aged (10-12?years) beagle dogs. In both groups, α-syn immunoreactivity was detected in neuropil of all the hippocampal sub-regions, but not in neuronal somata. In the aged hippocampus, α-syn immunoreactivity was apparently increased in mossy fibers compared to that in the adult dog. In addition, α-syn protein level was markedly increased in the aged hippocampus. On the other hand, GFAP and Iba-1 immunoreactivity in astrocytes and microglia, respectively, were increased in all the hippocampal sub-regions of the aged group compared to that in the adult group: especially, their immunoreactivity was apparently increased around mossy fibers. In addition, in this study, we could not find any expression of α-syn in astrocytes and microglia. These results indicate that α-syn immunoreactivity apparently increases in the aged hippocampus and that GFAP and Iba-1 immunoreactivity are also apparently increased at the regions with increased α-syn immunoreactivity. This increase in α-syn expression might be a feature of normal aging.</P>
Local Irritation Study of Recombinant Human Basic Fibroblast Growth Factor in Rabbits
Hyeon Cho,Dong Hwan Kim,Kyung Koo Kang,Byoung Ok Ahn,Beom Soo Park,Soo Hyung Kang,Won Bae Kim 한국독성학회 1999 Toxicological Research Vol.15 No.3
Primary and cumulative irritation of recombinant human basic fibroblast growth factor (bFGF) on the skin, primary irritation on ocular mucous membrane and cumulative local toxicity by subcutaneous injection were investigated using albino rabbits. The concentration of bFGF in liquid formulation was 0.01%, which is expected to be used for clinical practice. In primary and repeated dermal irritation studies, 0.01% bFGF solution did not induce any local response at the applied sites. Instillation of 0.01% bFGF solution to conjunctival sac also resulted in none of local changes of the conjuntivae and eyes throughout the observation period. Repeated subcutaneous injection of bFGF, however, induced edema, celluar infiltration, proliferation of fibroblasts, neovascularization and fibrotic changes confined to the injection site. These changes were thought to be attributable to its pharmacological effects. The present study demonstrates that 0.01% bFGF solution has no irritating potential when applied to intact skin.