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Arthanari Saravanakumar(아따나리 사라바나 쿠멀),Mani Ganesh(마니 가니쉬),Mei Mei Peng(펭메이메이),Abidov Sh Aziz(아비도프아지즈),Hyun Tae Jang(장현태) 한국산학기술학회 2014 한국산학기술학회 학술대회 Vol.2014 No.2
Antioxidant, antimycobacterial activity of opuntia ficus-indica fruit (OFI) extracts were evaluated according to seasonable cultivation. The antioxidant activities of OFI extracts were assessed by different in vitro methods and the total phenolic and flavonoid contents were also examined. The antimycobacterial activity was measured against Mycobacterium tuberculosis strains H37Rv (ATCC 27294) by microplate alamar blue assay (MABA) method. In antioxidant assay, methanol extracts of OFI in summer season showed the highest antioxidant activity in all tested methods and the lowest IC50wasobservedin2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Pearson correlation coefficient was evaluated and the results from the extracts of summer and rainy season OFI were significantly correlated with the total phenolic and flavonoid contents. However, the methanol extracts of OFI in summer showed high level of antimycobacterial activity against the strain of M. tuberculosis H37Rv, with minimum inhibitory concentration (MIC) of 50 µg/ml. The results from this study suggest that OFI could probably be an important source of antioxidant as well as antimycobacterial against M. tuberculosis.