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        Neurobehavioural Changes and Brain Oxidative Stress Induced by Acute Exposure to GSM900 Mobile Phone Radiations in Zebrafish (Danio rerio)

        Abhijit Nirwane,Vinay Sridhar,Anuradha Majumdar 한국독성학회 2016 Toxicological Research Vol.32 No.2

        The impact of mobile phone (MP) radiation on the brain is of specific interest to the scientific community and warrants investigations, as MP is held close to the head. Studies on humans and rodents revealed hazards MP radiation associated such as brain tumors, impairment in cognition, hearing etc. Melatonin (MT) is an important modulator of CNS functioning and is a neural antioxidant hormone. Zebrafish has emerged as a popular model organism for CNS studies. Herein, we evaluated the impact of GSM900MP (GSM900MP) radiation exposure daily for 1 hr for 14 days with the SAR of 1.34W/Kg on neurobehavioral and oxidative stress parameters in zebrafish. Our study revealed that, GSM900MP radiation exposure, significantly decreased time spent near social stimulus zone and increased total distance travelled, in social interaction test. In the novel tank dive test, the GSM900MP radiation exposure elicited anxiety as revealed by significantly increased time spent in bottom half; freezing bouts and duration and decreased distance travelled, average velocity, and number of entries to upper half of the tank. Exposed zebrafish spent less time in the novel arm of the Y-Maze, corroborating significant impairment in learning as compared to the control group. Exposure decreased superoxide dismutase (SOD), catalase (CAT) activities whereas, increased levels of reduced glutathione (GSH) and lipid peroxidation (LPO) was encountered showing compromised antioxidant defense. Treatment with MT significantly reversed the above neurobehavioral and oxidative derangements induced by GSM900MP radiation exposure. This study traced GSM900MP radiation exposure induced neurobehavioral aberrations and alterations in brain oxidative status. Furthermore, MT proved to be a promising therapeutic candidate in ameliorating such outcomes in zebrafish.

      • SCOPUSKCI등재

        Neurobehavioural Changes and Brain Oxidative Stress Induced by Acute Exposure to GSM900 Mobile Phone Radiations in Zebrafish (Danio rerio)

        Nirwane, Abhijit,Sridhar, Vinay,Majumdar, Anuradha Korean Society of ToxicologyKorea Environmental Mu 2016 Toxicological Research Vol.32 No.2

        The impact of mobile phone (MP) radiation on the brain is of specific interest to the scientific community and warrants investigations, as MP is held close to the head. Studies on humans and rodents revealed hazards MP radiation associated such as brain tumors, impairment in cognition, hearing etc. Melatonin (MT) is an important modulator of CNS functioning and is a neural antioxidant hormone. Zebrafish has emerged as a popular model organism for CNS studies. Herein, we evaluated the impact of GSM900MP (GSM900MP) radiation exposure daily for 1 hr for 14 days with the SAR of 1.34W/Kg on neurobehavioral and oxidative stress parameters in zebrafish. Our study revealed that, GSM900MP radiation exposure, significantly decreased time spent near social stimulus zone and increased total distance travelled, in social interaction test. In the novel tank dive test, the GSM900MP radiation exposure elicited anxiety as revealed by significantly increased time spent in bottom half; freezing bouts and duration and decreased distance travelled, average velocity, and number of entries to upper half of the tank. Exposed zebrafish spent less time in the novel arm of the Y-Maze, corroborating significant impairment in learning as compared to the control group. Exposure decreased superoxide dismutase (SOD), catalase (CAT) activities whereas, increased levels of reduced glutathione (GSH) and lipid peroxidation (LPO) was encountered showing compromised antioxidant defense. Treatment with MT significantly reversed the above neurobehavioral and oxidative derangements induced by GSM900MP radiation exposure. This study traced GSM900MP radiation exposure induced neurobehavioral aberrations and alterations in brain oxidative status. Furthermore, MT proved to be a promising therapeutic candidate in ameliorating such outcomes in zebrafish.

      • KCI등재

        A Palm Vein Recognition System based on a Support Vector Machine

        Vijayakumar Ponnusamy,Abhijit Sridhar,Arun Baalaaji,M. Sangeetha 대한전자공학회 2019 IEIE Transactions on Smart Processing & Computing Vol.8 No.1

        Palm vein authentication is among the recent research in the field of access control applications. Because palm veins are tough to forge, they act as a reliable metric in security applications. Accurate extraction of palm veins is challenging in the presence of various dynamics, such as variant light conditions, variations in palm vein patterns from person to person, the cleanliness of the hand, etc. This paper presents a robust recognition process that makes use of a ridge filter for vein pattern extraction, and local binary patterns (LBP) for feature extraction. The ridge filter takes the major eigenvalue of the Hessian matrix, which contains the second-order derivative of the image pixels. The eigenvalue is then processed using LBP feature extraction from the vein patterns. Finally, a support vector machine is used for classification of subsequent images. The result shows that the system can provide accuracy of 89%, with a computation time of 0.423s. The false acceptance rate and false rejection rate were also evaluated as benchmark parameters, which show significantly good performance.

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