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AYSE GUL KOCAK ALTINTAS,Cagri Ilhan 대한안과학회 2019 Korean Journal of Ophthalmology Vol.33 No.3
Purpose: To evaluate the changes in visual acuity (VA) and central macular thickness (CMT) after intravitrealdexamethasone (IVD) implantation in intravitreal bevacizumab (IVB) treatment-resistant cases with pseudophakiccystoid macular edema (PCME). Methods: This study included 10 PCME cases who underwent uneventful phacoemulsification and intraocularlens implantation with similar methods and six PCME cases referred to our hospital for treatment oflow VA after cataract surgery. Due to the persistence of PCME, both topical steroid and anti-inflammatorymedication were administered first, followed by IVB injection. IVD implantation was performed for all IVBtreatment-resistant cases. VA and CMT values were compared before and at three months after the first IVDimplantation. Results: The mean VA values before and at 3 months after the first IVD implantation were 0.69 ± 0.19 logarithmof the minimum angle of resolution (logMAR) (1.50 to 0.10 logMAR) and 0.26 ± 0.07 logMAR (1.00 to 0.00logMAR), respectively (p < 0.001). The mean CMT was 476.13 ± 135.13 mm (314 to 750 mm) and 294.06 ±15.26 mm (222 to 480 mm), respectively (p < 0.001). The mean number of implanted IVD was 1.44 ± 0.89 (1to 4) and the mean follow-up time was 7.4 ± 4.6 months (6 to 24 months). After IVD implantation therapy, themean VA and CMT values were 0.19 ± 0.05 logMAR (0.70 to 0.00 logMAR) and 268.38 ± 31.35 mm (217 to351 mm), respectively. Conclusions: To the best of our knowledge, this is the first report to show the efficacy of IVD implantationeven after repeated IVB injections in treatment-resistant PCME. IVD implantation is both a safe and effectivemethod for decreasing PCME after both uneventful and complicated cataract surgery.