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- 저자 : A Z M Raihanur Rahman (검색결과 2 건)
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( Abu Sadat Mohammad Nurunnabi ),( Sunjida Shahriah ),( A Z M Raihanur Rahman ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: In Bangladesh, several tools like Autism Behavior Checklist (ABC), Modifi ed Checklist for Autism in Toddlers (M-CHAT), Childhood Autism Rating Scale (CARS), and Autism Diagnostic Observation Schedule (ADOS) are widely used for either screening or diagnosis of autism; however, none of these measures have been validated for this population for autism spectrum disorders (ASDs) in Bangladesh. We evaluated the diagnostic reliability and validity of Help Autism Rating Scale (HARS), which was locally developed in 2012 and not widely used. Methods: This study was conducted in the Centre for Neurodevelopment and Autism in Children (CNAC) of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, on 200 Autistic Spectrum Disorder children in between January and December 2013. Item level scores of HARS were collected and analyzed. For internal consistency, Cronbach`s a coeffi cient was calculated. Convergent and divergent validity was calculated. The factor structure of HARS was demonstrated by principal components analysis. Results: The adequate face and content validity, HARS demonstrated good internal consistency (Cronbach`s a=0.962) and item-total correlation 0.790. The convergent validity between the HARS and BKT or GDS, calculated with Pearson`s product-moment correlation coeffi cient was 0.741, P=0.01. Divergent validity calculated by correlating HARS scores to ACTeRS showed non-signifi cant associations (r=-0.18; P=0.4) demonstrating that HARS discriminates autism from other childhood psychiatric disorders like ADHD. A 5-factor structure explained 43.34% of variance. Conclusions: The HARS has strong psychometric properties and is recommended for clinical and research work in autism spectrum disorders (ASDs) in Bangladesh.
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Sharmin Akter,A S M Bazlul Karim,Md Wahiduzzaman Mazumder,Md Rukunuzzaman,Khan Lamia Nahid,Bishnu Pada Dey,Maimuna Sayeed,A Z M Raihanur Rahman,Kaniz Fathema,Mukesh Khadga 대한소아소화기영양학회 2022 Pediatric gastroenterology, hepatology & nutrition Vol.25 No.5
Purpose: Perinatal cytomegalovirus (CMV) infection can lead to biliary atresia (BA) in different entities. This study aimed to compare the clinical, hematological, biochemical, and histological features of infants with BA based on their CMV immunoglobulin M (IgM) status at presentation. Methods: This cross-sectional descriptive study was carried out between January 2019 and June 2020 at the Department of Pediatric Gastroenterology and Nutrition at the Bangabandhu Sheikh Mujib Medical University (BSMMU) in Dhaka. Forty-three patients with BA were selected purposively and categorized into either the CMV IgM-positive or CMV IgM-negative BA group. Categorical variables were compared using Fisher’s exact test and chi-square tests, while the Student’s t-test and Mann–Whitney U-test were used to compare continuous variables. For all statistical tests, a p-value <0.05 was considered statistically significant. Results: Thirty-three (76.7%) of the cases were between 2 and 3 months of age on admission. The clinical, hematological, and biochemical parameters did not differ significantly between the CMV IgM-positive and CMV IgM-negative BA groups. Most (50.0%) of the CMV IgM-positive cases had fibrosis stage F2, while 43.5% of the CMV IgM-negative cases had fibrosis stage F3, with no significant difference between the groups (p=0.391). Conclusion: Our data shows no significant distinction between CMV IgM-positive and CMV IgM-negative BA, suggesting that CMV does not contribute to BA pathogenesis.
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