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박건영(Kun-Young Park),양미희(Mihi Yang),홍근혜(Geun-Hye Hong),이소영(So-Young Lee),이현승(Hyunseung Lee),이운재(Hyunseung Lee),박범용(Bumyong Park) 한국식품영양과학회 2023 식품산업과 영양 Vol.28 No.2
This paper introduces dietary salt kinds consumed in Korea and the researched health functionalities associated with them. Salt varieties include solar sea salt, refined salt, baking and melting salt (ex. Bamboo salt), purified salt, processed salt, deep-sea salt, and other types. The characteristics, manufacturing methods, and mineral content of these salts are outlined. While salt is essential for health, excessive intake can lead to various diseases such as cardiovascular diseases, hypertension, cancer, obesity, etc. WHO recommends a daily intake of 5 g of salt. However, researchers on salt and health suggest a range of 7.5~15 g/d (equivalent to 3~6 g of sodium), resembling a bell curve. Moreover, this paper emphasizes the importance of the type of salt consumed. Mineral-rich sea salt, particularly unrefined salt like solar sea salt and bamboo salt produced by baking sea salt in a clay pot, is highlighted for their functionalities. We also introduce the health benefits of using such salts in the production of fermented foods, particularly in the case of kimchi. The presence of salt in Korean fermented foods, known as the “Korean Paradox”, has been discussed, revealing the suppression of salt-related health risks through various probiotics, fermented metabolites and others. In Korea, solar sea salt and bamboo salt exhibited health benefits, especially their anticancer and antiobesity properties demonstrated in in vitro and in vivo studies. Deep-sea salt, sourced from the depths of the ocean, is considered safe and rich in minerals similar to solar sea salt. Although research on deep-sea salt itself and its utilization in fermented foods are still limited, the paper introduces its potential and prospects.
이빛나(Bitna Yi),신혜정(Hye Jung Shin),나현경(Hyunkyung Na),이나경(Na Kyung Lee),양미희(Mihi Yang) 환경독성보건학회 2009 환경독성보건학회지 Vol.24 No.4
Over the a few decades, the incidences of obesity and associated metabolic syndrome diseases have been increased dramatically and resulted in a global health crisis. Recent findings suggest endocrine disrupting chemicals (EDCs) as an obesogen, because they disrupt normal development and homeostatic controls over adipogenesis and energy balance in obesity. Furthermore, risk of cardiovascular disease and mortality is elevated among those who were obese during childhood. Thus, we focused on etiology of obesity in children and performed biological monitoring of bisphenol A (BPA), which is a broadly exposed EDC in environment. Study subjects were age and sex-matched obese and normal children in Seoul (N=52; age, 8.67±1.46 years). Exposure levels of BPA were analyzed with HPLC/FLD as a conjugated form in urine. As results, ranges of urinary BPA were 0~54.38 ㎍/g creatinine (median, 4.57 ㎍/g creatinine). Levels of urinary BPA were 1.7 fold higher in the obese children than those in the controls (medians of obese and control children, 7.31 and 4.25 ㎍/g creatinine, respectively, p=0.22). In the near future, enlarge scaled studies should be performed to confirm the risk of BPA for obesity.
양미희,양지연,윤여정 숙명여자대학교 약학연구소 2006 약학논문집-숙명여자대학교 Vol.23 No.-
Since 1980s, hyperlipidemia in Korea has been rapidly increased and its related cardiovascular diseases are one of the main causes of death in Korea. Thus, for effective prevention of hyperlipidemia, clarification of etiology of the hyperlipidemia in Koreans is required. In this study, we focused on polymorphisms in genes, which are involved in cholesterol-transfer, and -binding, e.g. cholesteryl ester transfer protein (CETP) and apolipoprotein E (APOE). Study subjects were 257 Koreans (cases who had hyperlipidemia, LDL≥130, N=47; controls, N=210; Men, 62%). Genetic polymorphisms were determined by PCR-RFLP, and single base primer extension assays. As results, allele frequency of the CETP -Tag IB1 was significantly higher in cases than that in controls (p<0.05). When age and BMI were controled for statistics, there was 2.3 fold increase of OR (95%CI, 1.1-5.1) for hyperlipidemia in the Bl/Bl homozygotes compated to the B1/B2 heterozygotes. However, 2 SNPs, CI 12R and R158C of the APOE, or 5 haplotypes of the 2 SNPs were not associated with hyperlipidemia risk. Therefore, presence of the CETP-B1 allele has a potential of risk for Korean hyperlipidemia.