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RISS 인기검색어
- 검색키워드
- 저자 : 황보상(Bo Sang Hwang) (검색결과 3 건)
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Rehmanniae Radix에 의한 가토 동방결절 및 유두근의 활동전압의 변동
황보상(Hwang, Bo-Sang),고상돈(Koh, Sang-Don),신홍기(Shin, Hong-Kee),김기순(Kim, Kee-Soon) 대한생리학회 1985 대한생리학회지 Vol.19 No.2
The present study was undertaken in order to investigate effect of ethanol extract of Rehmanniae radix(RREE) on electrophysiology of sinus node and papillary muscle. Rehmanniae radix is a herbal medicine which has been known to have diuretic, antipyretic, hemopoietic and cardiotonic effects. Action potentials were recorded by means of glass capillary microelectrode(technique) in rabbit sinoatrial nodal cells and papillary muscle cells which were superperfused with either tyrode solution or tyrode solutions containing different amount of RREE. The results obtained were as follows ; 1) In both central and peripheral nodal cells maximum diastolic potential (MDP) and amplitude of action potential (APA) were not affected by RREE. 2) Action potential duration as expressed APD<sub>60</sub>(time to 60% repolarization) of central and peripheral pacemaker cells were significantly prolonged following perfusion with tyrode solution containing 0.1% RREE. 3) The rates of spontaneous firing from central pecemaker cell were decreased by RREE at concentration of 0.05% and 0. 1% while spontaneous rhythm of perinodal cell was decreased by 0.1% RREE. 4) The action potential duration of papillary muscle as expressed APD<sub>60</sub> were prolonged by 0.1% RREE.
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노즐의 이동 및 각도 변화가 전기방사시스템의 전기장에 미치는 영향 해석.
이정호(Jung Ho Lee),박찬희(Chan Hee Park),양수진(Su Jin Yange),문호준(Ho Jun Moon),김경화(Kyung Hwa Kim),황보상(Bo Sang Hwang),김철생(Cheol Sang Kim) (사)한국CDE학회 2013 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2013 No.1
Robot-assisted the multi nozzle device and Nozzle less (free liquid surface) technology development are the innovative ways for the produce nano fiber. However those studies which use angled multi nozzle and electric field were not performed at all. Therefore, we developed new electro-spinning system that can move the position of the angled nozzle. And we compared simulation result and experimental results regarding the electric field between the nozzle and collector tips. Finally, interference of the electric field is the largest when the nozzle angles is 90°. And even if the robot is move between the nozzle and the collector the direction of the electric field was maintain steady state. Also, the results of experiment which measuring the change of the electric field in electro-spinning system by applying the noise filter were obtained similar results.
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Taurine이 histamine에 의해 유발된 가토 동방결절 세포의 막전압 및 부정박동에 미치는 효과 : Antiarrhythmic Effect of Taurine
황보상,김진혁,고상돈,신홍기,김기순 한양대학교 의학교실 1988 한양의대 학술지 Vol.8 No.2
Effects of taurine and histamine on the electrophysiological characteristics of the rabbit sinus node cells were investigated by a conventional microelectrode technique. Also studied was the effect of taurine on histamine-induced changes in the action potential of the pacemaker cells, as well as on histamine-induced arrhythmias. When the sinus node cells were exposed to histamine the overshoot potential, consequently action potential was decreased, action potential duration was shortened and the rate of spontaneous firing increased markedly. Effect of histamine on the cellular potential peaked between 5 to 10 minutes after superfusion of the cardiac pacemaker cells. On the other hand, taurine (0.01-0.5%) did not affect the transmembrane potential of the rabbit sinus node cells. After pretreatment of the cardiac pacemaker cells with taurine, effect of histamine on the action potential amplitude was depressed prominently whereas action potential duration was not altered by histamine. Histamine-induced tachycardia or dysrhythmia were significantly supressed in 1-2 hours following superfusion of the sinus node cells with taurine solution. The possible mechanism underlying antiarrhythmic action of taurine on histamineinduced arrhythmia was discussed. It is concluded that taurine has a protective action against adverse effects of histamine on the cardiac pacemaker cells of the rabbit heart.
ScienceON
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