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박태운 ( Tae Woon Park ),우명렬 ( Myoung Lyeol Woo ),한서구 ( Seo Goo Han ),김정훈 ( Jeong Hun Kim ),전병수 ( Byung Soo Jeon ),이상철 ( Sang Cheol Lee ),송지선 ( Ji Sun Song ),윤수영 ( Soo Young Yoon ) 대한신장학회 2006 Kidney Research and Clinical Practice Vol.25 No.6
Classic polyarteritis nodosa (c-PAN), first described by Kussmaul and Maier in 1866, is a systemic illness characterized by necrotizing inflammation of mediumsized arteries. Rapid progressive renal failure is very rare in c-PAN in contrast to microscopic polyangiitis (MPA). We report a case of c-PAN presented with rapidly progressive renal failure. A 58 year-old male was referred to our hospital for evaluation of asthenia and right visual loss. An increase in serum creatinine level was developed in the 6th day of hospitalization and acute renal failure was aggravated rapidly. Renal biopsy showed the transmural fibrinoid necrosis of small and medium sized arteries with few glomerular crescents. P-ANCA was detected in serum, and all clinical and laboratory findings supported the diagnosis of c-PAN. He was treated with pulse methylprednisolone, followed by oral corticosteroid and cyclophosphamide, and received temporary hemodialysis. After the treatment, he recovered and was discharged but his visual defect was irreversible despite the treatment. (Korean J Nephrol 2006;25(6):1029-1034)
가역성 양측 기저핵 병변을 동반한 반복적인 급성 요독성 뇌병증
최자성 ( Ja Sung Choi ),김정훈 ( Jeong Hun Kim ),전병수 ( Byung Soo Jeon ),박경석 ( Kyung Suk Park ),우명렬 ( Myoung Lyeol Woo ),이상철 ( Sang Choel Lee ),이은자 ( Eun Ja Lee ),윤수영 ( Soo Young Yoon ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.1
Uremic encephalopathy is a well-known complication in uremia and rarely occurs with involuntary movements which represent basal ganglia lesion. We experienced a cases of recurrent acute uremic encephalopathy associated with reversible bilateral basal ganglia lesion. A 49-year-old man with end stage renal disease due to diabetic nephropathy on continuous ambulatory peritoneal dialysis (CAPD) treatment for the last 2 months was admitted for mental change. His blood sugar was 60 mg/dl, and his mentality was recovered after glucose solution infusion. Five days after admission, he suddenly developed dysarthria and chorea. Brain magnetic resonance imaging (MRI) demonstrated low and high signals on bilateral basal ganglia in T1-weighted and T2-weighted images, respectively. After intensified CAPD treatment, his neurologic manifestations were resolved. One month after discharge, follow-up brain MRI showed decreased size of low attenuation on the basal ganglia. Two months later, he repeatedly developed dysarthria and involuntary movement of extremities. Newly developed bilateral symmetric T1 low and T2 high signal lesion on the basal ganglia was repeatedly observed on brain MRI. At that time, (his) Kt/V was 1.33. So we decided on him to switch from CAPD to hemodialysis, after then his symptoms disappeared.
성장호르몬 결핍 성인에서 성장호르몬 투여가 심혈관 질환의 표지자에 미치는 영향
최형섭 ( Hyung Seob Choi ),김상수 ( Sang Soo Kim ),고근준 ( Kun Joon Ko ),이은재 ( Eun Jae Lee ),박일운 ( Il Woon Park ),박태운 ( Tae Woon Park ),한서구 ( Seo Goo Han ),우명렬 ( Myoung Lyeol Woo ),조지훈 ( Ji Hoon Cho ),홍성일 ( S 대한내과학회 2005 대한내과학회지 Vol.68 No.5
목적 : 성인 성장호르몬 결핍증 환자에서 3개월간의 성장호르몬 투여가 체중, 체질량지수, 허리둘레와 같은 신체검사결과, 혈당, 지질수치, 혈압 등의 잘 알려진 심혈관 질환의 위험인자들과 C-반응단백 및 PAI-1과 같은 염증반응인자들에 미치는 영향을 위약-대조군 연구를 통해 조사하였다. 방법 : 총 37명의 성인형 성장호르몬 결핍증 환자들과 65명의 정상인이 임상시험에 참여하였다. 시험시작 전과 3개월 후에 키, 몸무게, 허리둘레, 엉덩이둘레를 측정하였 Background : Subjects with growth hormone-deficiency (GHD) have increased cardiovascular mortality, and growth hormone (GH) replacement may modulate cardiovascular disease risk. Therefore, we evaluated the effects of GH administration on the markers of ca
후천성 면역 결핍증 환자에서 발현된 Rhizobium radiobacter에 의한 원발성 균혈증 1예
박일운,박태운,한서구,조지훈,우명렬,이혁민,이꽃실 대한감염학회 2006 감염과 화학요법 Vol.38 No.6
Rhizobium radiobacter는 면역능력이 떨어져 있는 환자에서 유치도관과 관련하여 기회감염을 일으키지만 지역획득 감염을 일으킬 수도 있다. 저자들은 AIDS 환자에서 발생한 Rhizbium radiobacter에 의한 원발성 균혈증을 경험하였으며, 항균요법으로써 성공적으로 치료하였기에 문헌고찰과 함께 보고하는 바이다. Rhizobium radiobacter, which has been previously discribed as Agrobacterium radiobacter, is a group of phytopathogenic organisms widely distributed in soil. Over the past decade, increasing number of infections due to Rhizobium radiobacter has been reported. Rhizobium radiobacter is now recognized as rare human pathogens affecting mostly immunocompromised hosts and is an opportunistic pathogen often associated with indwelling catheters. We report a case of bacteremia due to Rhizobium radiobacter in an acquired immunodeficiency syndrome (AIDS) patient. The patient was admitted for fever. In the blood culture, Rhizobium radiobacter was isolated. These symptoms and signs were successfully resolved with antibiotics.