폐경기 이후 부인에 병발한 융모암 1예

신면우(MW Shin),서호석(HS Suh),이건용(KY Lee),문병준(BJ Moon),이선경(SK Lee) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.5

Long latent development of choriocarcinoma should be defined as one that occured more than 2 years after the cessation of pregnancy. Authors have recently experienced an unusual case of choriocarcinoma which developed 13 years after the last pregnancy in postmenopausal woman. An unusual case of long latent choriocarcinoma is presented with brief review of patient literature.

분만예정일 초과

신면우(MW Shin) 대한산부인과학회 1971 Obstetrics & Gynecology Science Vol.14 No.6

분만예정일 초과를 보인 환자군과 대조군간에서 분만방법을 비교한 바 산과수술인 흡인분만 및 제왕절개수술등이 분만예정일 초과를 보인 환자군에서는 대조군에 비해 월등히 고율이었다. A total of 3,559 births which occurred after 30weeks of gestation at The Seoul National University Hospital during the period from January 1, 1967 to December 31, 1970 were reviewed. The duration of prtegnancy was calculated by Nagele`s rule with correction for cycles greater or less than 28 days. A pregnancy lasting 42 weeks or more from the first day of the last menstrual period was considered postdate, this arbitrary period being the one most commonly described in the literature. Patients whose menstrual cycles were grossly irregular were not included in this study. The purpose of this study were;(1) to asses the importance of certain conditions suggested as being significant in the etiology of prolonged pregnancy;(2) to determine the effect of prolonged gestation upon th fetus; and (3) to delineate a plan for the management of patients in whom pregnancy is prolonged past the expected date of confinement. Of these 3,559 births, 563 were postdate pregnancy. The following factors were analyzed: distribution of over-all births in relation to length of gestation, age, parity, birth weight, fetal distress, perinatal death, duration of labor, and method of delivery. The findings in paints in whom pregnancy prolonged were compared with over-all clinic experience for the same period. the results obtained in this study were as following. 1. A series of 563 postdate pregnancies is presented. The incidence of prolonged pregnancy was 15.6 percent, with the highest incidence occurring in the 25 to 29 year age group. 2. Of these 563 births, 51.2 percent were to multiparas and 48.8 percent were to primiparas. 3. The incidence of heavier babies in postdate deliveries was apparent and had been noted also by other investigators. 4. Fetal distress ocurred more commonly in the postdate group (9.6 percent) than in the control group (5.7 percent), especially in primiparous patients (11.4%). A trend toward a greater incidence of fetal distress as the postdate period lengthens was noted. 5. Perinatal mortality rate in the postdate group was 55.1 per thousand as compared to a 64.9 per thousand perinatal mortality in over-all deliveries. A trend toward a greater rate of fetal mortality as the baby weight increases and the postdate period lengthens was noted, especially in primiparous patient. 6. A trend toward a prolonged labor was noted in primiparous paients with postdate pregnancy. 7. A significantly increased incidence of operative delivery was noted. In particular, the primiparous patient with postdate pregnancy frequently came to operative delivery. The cesarean section rate was increased in the postdate group compared to the control group.

임신 빈혈에 관한 연구

신면우(MW Shin),이현식(HS Lee) 대한산부인과학회 1972 Obstetrics & Gynecology Science Vol.15 No.12

임신 빈혈에 관한 연구를 통해 빈혈환자의 대부분은 철분결핍빈혈환자이었다. This study is to investigate the status of pregnancy anemia in 127 Korean pregnant women who have had antenatal care at the Dept. Of Obst. and Gyne. Seould National University Hospital and admitted for delivery. The changes in homoglobin, hematocrit, mean corpuscular hemoglobin concentration, protein total, serum albumin, serum iron and total iron binding capacity during pregnancy have been observed. The followings are the summary result of this study. 1. The average hemoglobin levels were 11.8±1.22gm/100ml in first trimester, 11.6±1.42gm /100ml in second trimester, 11.2±1.44gm/100ml in third trimester and 11.1±1.36gm/100ml in puerperiu. The incidence of severe anemia with hemoglobin level below 10.0gm/100ml was 1.26 per cent of the total and onother 48 per cent were classified as mild anemia with hemoglobin level between 10.0gm/100ml and 12.0gm/100ml. 2. The majority of anemia cases were associated with serum iron and albumin deficiency. The incidence of serum iron deficiency was 79 per cent among the cases with severe anemia.

자궁태아사망을 초래한 제대진결절의 1례

신면우(MW Shin),이효표(HP Lee),신경자(KJ Shin),나태경(TK Rha) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.10

The occurrence of true knot of the umbilical cord is rare and occasionally they may be pulled so tight as to become compressed and lead to fetal distress and death. A case of true knot of umbilical cord resulting in fetal death in utero is presented with the brief review of the literatures.

단백성 호르몬의 면역학적 연구

신면우(MW Shin),류장희(CH Yu),강소자(Kang SJ) 대한산부인과학회 1971 Obstetrics & Gynecology Science Vol.14 No.12

단백성 호르몬의 면역학적 연구를 시행하여 보고하는 바이다. For the immunologic determination of H.C.G. in both urine and serum in the patients of hyperemesis gravidarum and the comparison of the concentration of H.C.G. in both serum and amniotic fluid of term pregnant women, basic experiments and semi-quantitative assay has been performed by means of hemagglutination inhibition technique. The obtained results are as following. 1. H.C.G. of relatively high purity(5,427 IU/mg.) was used as antigen and high titer of antiserum was obtained even with relatively small amount of antigen through booster injection of antigen and complete Freund`s adjuvant. 2. The specificity of the obtained antiserum has been confirmed by the neutralization test of biologic activity of H.C.G. on the weight of immature rat ovary. The analysis of the purity of H.C.G. with Onchterlony test revealed that used H.C.G. contained negligible amount of other proteins. 3. In the patinet of hyperemesis gravidarum, the titer of H.C.G. in both serum and urine were significently higher than that of normal pregnancy at the same period. 4. The severity of emetic symptoms seems relatively correlate with the titer of H.C.G. in both urine and serum. 5. The titer of H.C.G. in both serum and amniotic fluid of 40 term pregnant women was 28.0IU/ml. 5.3IU/ml. respeefively. The ratio of H.C.G. concentration of amniotic fluid to serum was 17.3%.

질횡격막의 1례

신면우(MW Shin),이효표(HP Lee),고영우(YW Koh),이진용(JY Lee) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.10

A case of transverse septum of vagina, obscuringthe cervix, with a cental opening of a few millimeters in diameter is presented with a brief review of the concerned literature.

융모성 종양 및 임신중독증 환자의 혈청중 H.C.G의 동태에 관한 면역학적 연구

신면우(MW Shin) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.3

Setum H.C. G level has been determined in patients with trophoblastic diseases and severe toxemia by the hemagglutination inhibition technic. The results are as follows: 1. A relatively high titer of aniserum was obtained with relatively pure H.C.G. (5,427 I.U./mg) 2. The specificity test for the obtained antiserum has been confirmed by the neutralization test of biological activity of H.C.G. on the weight of immature rat ovary. 3. Ouchterlony test for the analysis of the purity of H.C.G. revealed only one clear precipitin line between antigen and antiserum, indicating that the used H.C.G. contained negligible amount of other protains. 4. Serum was treated with acetone and H.C.G. containing fraction was washed with absolute alcohol and ether, and the recovery rate of H.C.G. with the aceton precipitation method was about 95per cent. 5. In hydatidiform mole, the mean value of H.C.G. in serum was 644.9 I.U./ml which was about 10 times higher than the level found in the normal pregnancy at the corresponding duration. 6. The serum concentration of H.C.G. in choriocarcinoma was also remarkably high, which was about 2-3times higher than of normal pregnancy. 7. In severe toxemia, H.C.G. concentration in serum revealed considerably high value within the range of uncomplicated pregnancy(t=4.84>2.77∴ p 0.01).

거대생존아만출을 포함한 복강임신의 2증예

신면우(MW Shin),김득구(DK Kim),김영철(YC Kim),박재우(JU Park) 대한산부인과학회 1965 Obstetrics & Gynecology Science Vol.8 No.12

Two cases of abdominal pregnancy are presented. Which we experienced in Nov. 1962, and Feb. 1963. It was uncertain that the 1st case was primary or secondary abdominal pregnancy or ovarian pregnancy. The 2nd one was a case of secondary abdominal pregnancy which was produced by perforation of uterine wall and evacuation of the conceptus into peritoneal cavity during D&C. It had been performed to interrupt the pregnancy at the 2nd month. The live female baby1, weighing 4.7kg was delivered abdominally. A brief review of the literature of abdominal prepnancy was done.

원발성 난소임신의 1례

신면우(MW Shin),지제근(JG Chi),이강현(KH Lee),윤혜숙(HS Yun),주덕상(DS Chu),박효숙(HS Park) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.12

Ovarian preqnancy is a type of ectopic preqnancy and the four criteria of Spiegelberg should be fultilled in disagnosis. Recently we had a chance to study a case of ovarian pregnancy at the Dept. of Obstetrics and Gynecology, Seoul National University Hospital. Acase of ovarian pre- gnaney is presented with brief review of the literature.

양수단백과 모체 및 태아 혈청 단백의 여지 전기영동상에 대하여

신면우(MW Shin),박성기(SK Park),백운송(US Paik),박성관(SK Park) 대한산부인과학회 1963 Obstetrics & Gynecology Science Vol.6 No.9

1) Amniotic fluid from fourteen cases of pregnant women was fractionated for proteins by paper elctrophoresis and the resulting patterns were compared with those of maternal and fetal serum proteins. 2) A/G ratio was highest in amniotic fluid. Alpha-2 and gamma globulin concentration in amniotic fluid was significantly lower than in maternal serum protein, suggesting the possiple role of iotic fluid was significantly lower than in maternal serum protein, suggesting the possiple role of serum molecular weight in traversing fetal membrane. 3) The relative concentration of amniotic fluid proteins was similar to maternal serum protein pattern. Furthermore, the patterns showed a closer similarity to those of the dilysate of maternal through fetal membrane against normal saline solution. 4) No Particularly remarkable changes in amniotic fluid protein patterns were observed in two respective cases og hydramnios and mild pre-eclampsia. 5) Trans-addominal amniocentesis in eight cases proved to be a satisfactory method of obtaining good samples of amniotic fluid with little danger. 6) Brief review of literatures was made in regard to the origin of amnioitic fluid protein and its nutritional value to the fetus.