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민경은(Gyeong Eun Min),전승현(Seung Hyun Jeon) 대한비뇨기종양학회 2010 대한비뇨기종양학회지 Vol.8 No.1
Transurethral resection of bladder tumor (TURB) is a standard method for treatment and diagnosis of non-muscle invasive bladder tumor. However, early recurrence rates after TURB is relatively high, 15% in a single tumor, and up to 45% in multiple tumors, which do not seem to be acceptable. These high recurrence rates may be caused by incomplete tumor resection, aggressive tumor biology, or implantation of tumor cells shed during surgery. Herein, we investigated the ways to improve the outcomes of TURB.
투명세포신세포암에서 NF-κB의 발현과 임상병리인자에 관한 분석
이영(Young Lee),최정혁(Jeonghyouk Choi),이동기(Dong-Gi Lee),유구한(Koo Han Yoo),민경은(Gyeong Eun Min),이형래(Hyung-Lae Lee),원규연(Kyu Yeoun Won),임성직(Sung-Jig Lim) 대한비뇨기종양학회 2016 대한비뇨기종양학회지 Vol.14 No.2
Purpose: A multi-subunit transcription factor NF-κB is associated with anti-apoptotic signals in several cancers including renal cell carcinoma (RCC). In this study, we investigated whether the expression levels of the NF-κB were related to the clinical properties of human renal cell carcinoma such as nuclear grade, TNM stage, and recurrence free survival. Materials and Methods: Patients who were diagnosed with clear cell RCC between January 2006 and February 2013 were included. Clinicopathological data and survival were investigated. The expressions of NF-κB were investigated by performing immunohistochemical staining on 61 clear cell RCC. The expression levels of NF-κB were divided two groups by the expression levels. Results: Results on the expression of NF-κB were not significant. Analysis of NF-κB expressions is not associated with any of the clinical properties including age, nuclear grade and TNM stage (p=0.613, p=0.059, p=0.107, p=0.570, and p=0.760, respectively). Also, a statistically correlation was not observed between recurrence free survival and NF-κB expression levels (p=0.573). Conclusions: The expressions of the NF-κB were not associated with the clinical properties of clear cell RCC such as age, nuclear grade, TNM stage, and recurrence free survival.