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      • 저칼륨성 가족성 주기성 마비증 1예

        김계남,노재경,김영채,이순남,경난호,박이갑 梨花女子大學校 醫科大學 醫科學硏究所 1984 EMJ (Ewha medical journal) Vol.7 No.3

        A case of hypokalemic familial periodic paralysis is presented and the litures are reviewed. A 15-year-old boy was admitted to Ewha Womans University Hospital with chief complaints of paralysis of both extremities and trunk on awaking in the morning. He had a history of quadriplegia, 8 months ago. Laboratory study revealed a hypokalemia(1.6mEq/L) and biopsy specimen taken from the gastrocnemius muscle showed mild vacuolization. After treatment with potassium chloride, paralysis was completely recovered.

      • 당뇨병성 케톤산혈증에서의 대사장애에 관한 연구 : 인을 중심으로 Including Serum Phosphate

        김계남,경난호 梨花女子大學校 醫科大學 醫科學硏究所 1985 EMJ (Ewha medical journal) Vol.8 No.4

        The ketaocidosis is one of the acute complication in patients with diabeds mellitus and its mortality rate is much decreased after low dose insulin infusion therapy. Clinically, diabetic ketoacidosis showed metabolic abnormalities such as metabolic acidosis, fluid-electrolyte imbalance and hypophosphatemia. Many studies are now available about its mechanism or treatment for the better prognosis. This study included 20 cases of diabetic ketoacidosis who had been admitted to the Department of Internal Medichine at Ewha Womans University Hospital, from March 1982 to May 1984. We observed the correlation between serum phosphate and other metabolic abnormalities. The results obtained were as follows; 1) Diabetic ketoacidosis was more common in female than male. The ratio of male to female was 1:1.85. The age incidence was the highest in 6th decade(35%). The first diagnosis was 3 cases(15%). 2) The commonest precipitating cause was infection(8 cases, 40%). 3) The requiring fluid amount was 6.0+3.01 to correct fluid-electrolyte imbalance. The mean value of serum osmolarity was 309.0+23.7 mOsm/L, serum sodium 130±17.9-mEq/L serum potassium 3.0+1.3㎎/㎗, urea nitrogen 30.4+20.0㎎/㎗, bicarnate 10.85+8.5mEq/㎗ and blood ketone from ++ to +++. 4) The mean value of blood glucose was 575.6+242.8㎎/㎗. The rate of decrease of glucose was 82.7+47.2㎎/㎗/hr after insulin therapy. The time of decreased blood sugar level below 250㎎/㎗ was 5.72+2.5hr and the priming dose of insulin was 11.4+6.8u. The infusion rate of insulin was 4.9+1.56u/hr and total amount of insulin was 56.6+28.7u for correction of electrolyte imbalance. 5) The comparison of group A(↓serum phosphate 2.5㎎/㎗, 5 cases) with group B(↑serum phosphate 2.5㎎/㎗, 10 cases) : The mean value of serum phosphate was 1.5+0.4㎎/㎗ in group A and 3.8+09㎎/㎗ in group B. The mean value of glucose was significantly higher in group A(796.6+312㎎/㎗) than in group B(508+164.7㎎/㎗)(P<0.005) and the mean value of the serum pH was significantly lower in group A(7.058+0.124) than in group B(7.339+0.163)(P<0.01). However there was no significant correlation between two groups in serum osmolarity, sodium, potassium, insulin amount and correction time. 6) The common complications of ketoacidosis were infection(3 cases, 15%) and myocardial infarction(2 cases, 10%). The mortality rate was 5%(1 case) and its cause of death was sepsis with disseminated intravascular coagulation.

      • 환약(해구신) 복용에 의한 연중독 치험 1예

        김현숙,김계남,오도연,신길자,이우형 梨花女子大學校 醫科大學 醫科學硏究所 1983 EMJ (Ewha medical journal) Vol.6 No.4

        A case of lead poisoning is presented and recent litures are reviewed. A 47-year old male had been admitted to Ewha Womans University Hospital in March 1983 with chief complaints of abdominal colic & distention, nausea and tingling sensation of lower extremities after ingestion of herb pills(HAE GU SIN). Laboratory examinations are as follows; anemia with hypocromic, microcytic, basophilic stippling of erythrocytes in peripheral blood and bone marrow. Blood level of lead was 34.6mcg/㎗, urine level of lead was 128.4mcg/L, coproporphyrine and △-ALA in 24hours urine were 270.8mcg/L, 19.9㎎/L respectively. After treatment with BAL for 1 day, blood level of lead was 30.4mcg/㎗, urine level of lead was 2988.6mcg/L, coproporphyrine and △-ALA in 24hours urine were increased to 667.2mcg/L, 5.5㎎/L respectively and quantitative analysis of herb pills revealed 10% of containing lead.

      • 양성 비기능성 췌장도세포종 1례

        노재경,김계남,윤견일,박이갑,박문규,최용만,한운섭 梨花女子大學校 醫科大學 醫科學硏究所 1984 EMJ (Ewha medical journal) Vol.7 No.4

        The nonfunctioning islet cell tumors of pancreas are not associated with obvious sign and symptoms of hormone overproduction. Symptoms, most commonly pain and jaundice, are due to the mass effect of the tumor and invasion of the surrounding structures, and unlike functioning tumors, the location of the tumor has a direct bearing on the patient's symptoms. We have experienced a case of benign nonfunctioning islet cell tumor of the pancreas in 47-year-old female. She was admitted to our hospital due to palpable large mass of her abdomen. She had no obvious sign and symptoms of hormone overproduction. The exploratory laparatomy was done under the impression of retroperitoneal tumor with the information of radiologic finding and abdominal C-T scan. The pathologic diagnosis was benign nonfunctioning is-let cell tumor of the pancreas.

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