Interaction of Coping Styles and Psychological Stress on Anxious and Depressive Symptoms in Chinese Breast Cancer Patients

Wang, Xi,Wang, Shu-Sen,Peng, Rou-Jun,Qin, Tao,Shi, Yan-Xia,Teng, Xiao-Yu,Liu, Dong-Gen,Chen, Wei-Qing,Yuan, Zhong-Yu Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Purpose: This study aimed to assess possible interactive effects of coping styles and psychological stress on depression and anxiety symptoms in Chinese women shortly after diagnosis of breast cancer. Methods: Four hundred and one patients with breast cancer were face-to-face interviewed by trained research staff according to a standardized questionnaire including information on socio-demographic characteristics, psychological stress, coping styles, and anxiety and depressive symptoms. Interactive effects were assessed by hierarchical multiple regression analyses. Results: There were significant associations of the four domains of psychological stress with anxiety and depressive symptoms except for the relationship between "worrying about health being harmed" and depressive symptoms. "Abreaction coping behavior" and "escaping coping behavior" significantly increased the level of both anxiety and depressive symptoms; whereas an "active coping style" reswulted in significant decrease. The interaction of "active coping behavior" with "worrying about health being harmed" significantly increased the risk of the anxiety symptoms, while adopting "self-relaxing coping behavior" was associated with significant decrease. The interaction of "worry about daily life and social relationship being restricted" with "escaping coping behavior" significantly increased the risk of the depressive symptoms. Conclusions: The results of this study suggest that certain coping styles might moderate the association of psychological stress with anxiety and depressive symptoms in Chinese women with breast cancer.

Value of PAX1 Methylation Analysis by MS-HRM in the Triage of Atypical Squamous Cells of Undetermined Significance

Li, Shi-Rong,Wang, Zhen-Ming,Wang, Yu-Hui,Wang, Xi-Bo,Zhao, Jian-Qiang,Xue, Hai-Bin,Jiang, Fu-Guo Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

Background: Detection of cervical high grade lesions in patients with atypical squamous cells of undetermined significance (ASCUS) is still a challenge. Our study tested the efficacy of the paired boxed gene 1 (PAX1) methylation analysis by methylation-sensitive high-resolution melting (MS-HRM) in the detection of high grade lesions in ASCUS and compared performance with the hybrid capture 2 (HC2) human papillomavirus (HPV) test. Materials and Methods: A total of 463 consecutive ASCUS women from primary screening were selected. Their cervical scrapings were collected and assessed by PAX1 methylation analysis (MS-HRM) and high-risk HPV-DNA test (HC2). All patients with ASCUS were admitted to colposcopy and cervical biopsies. The Chisquare test was used to test the differences of PAX1 methylation or HPV infection between groups. Results: The specificity, sensitivity, and accuracy for detecting CIN2 + lesions were: 95.6%, 82.4%, and 94.6%, respectively, for the PAX1 MS-HRM test; and 59.7%, 64.7%, and 60.0% for the HC2 HPV test. Conclusions: The PAX1 methylation analysis by MS-HRM demonstrated a better performance than the high-risk HPV-DNA test for the detection of high grade lesions (CIN2 +) in ASCUS cases. This approach could screen out the majority of low grade cases of ASCUS, and thus reduce the referral rate to colposcopy.

Experimental Investigation of Ozone Decomposition in Diesel Particulate Filter Regeneration with Non-Thermal Plasma Technology

Wang Weikai,Cai Yi-xi,Shi Yunxi,Wang Jing,Zhao Nan,Ji Liang 한국자동차공학회 2021 International journal of automotive technology Vol.22 No.4

A non-thermal plasma (NTP) reactor was used to generate ozone for diesel particulate filter (DPF) regeneration. The kinetic mechanism of ozone thermal decomposition reaction is explored, and the effect of temperature on the change of ozone concentration is analyzed. The changes of the internal temperature and the concentration of regeneration products such as CO2 and CO during the regeneration under constant temperature and non-constant temperature conditions are then studied and the influence of different regeneration environments on the regeneration is analyzed in combination with the decomposition law of ozone. In the non-constant temperature condition, DPF surface temperature changes significantly with time. The results show that when using an NTP reactor to generate ozone, the activation energy of the decomposition reaction is 2.80755 × 104 J/mol and the law of thermal decomposition reaction can be described as 190.76 . /. During DPF regeneration, the overall regeneration rate and ozone utilization rate in the nonconstant temperature environment are higher than in the constant temperature environment and the temperature change (delta-T) peak rises with the increase of PM deposition. The regeneration with NTP under non-constant thermal condition is an effective way to improve the efficiency of DPF regeneration.

Experimental Study on Mechanical Properties and Toughness of Q460C High-strength Steel and Its Butt Welded Joint at Low Temperature

Xi-yue Liu,Yuan-Qing Wang,Liang Zong,Yun Lin,Yong-Jiu Shi 한국강구조학회 2014 International Journal of Steel Structures Vol.14 No.3

Compared with the conventional steel structure, the high-strength steel structures are at more risk of brittle fracture, especiallyin cold regions. In the present study, a series of tests (such as uniaxial tensile test, Charpy impact test and three-point bendingtest) were carried out at low temperature to investigate the mechanical properties and toughness of Q460C steel and its buttwelded joint, fracture micro-mechanisms were analyzed as well. The ductility indices and the toughness indices all decreasewith temperature decreases, the heat affected zone (HAZ) in welded joint is more critical to fracture than the base material. The fracture toughness of high-strength steel Q460C is relatively lower than the other three conventional steels (i.e. Q235, Q345and Q390). In this study, rich experimental data were collected so as to provide reference for the fracture resistant design ofhigh-strength steel structures in cold regions.

Comparative study of tip leakage vortex trajectory and cavitation in an axial flow pump with various tip clearances

Xi Shen,Desheng Zhang,Bin Xu,Haoran Wu,Peng Wang,Weidong Shi 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.3

In order to analyze the effect of blade tip-gap size on the tip leakage vortex (TLV) dynamics and TLV-induced cavitation, a scaled axial flow pump model was created and numerically studied by the combination of an improved SST k-ω turbulence model and a homogeneous cavitation model. The trajectories of TLV core was obtained by using the swirling strength method at different tip-gap sizes vary significantly. The scale of TLV increases as the tip-gap size increases, and the starting point of TLV is sliding further downstream along the blade chord. The angle between the blade suction surface and the TLV also presented an increasing trend with the tip-gap size. The statistics of the velocity normal to the tip chord, as well as the turbulent kinetic energy (KTE) distributions were employed to illustrate a more disordered flow field, which was generated in the tip clearance in a larger amount of leaking flow due to the increased tip-gap size. The in-plain static pressure and vapor volume fraction distributions at different blade chord sections, coupled with three-dimensional cavitation patterns among three tip gaps, are further analyzed to verify the wandering motion of TLV, which shows good agreement with the visualization experiment. Considering the adverse effect of the TLV cavitation, a small tip gap is recommended for improving the axial flow pump performance.

Toll-like Receptor 5 Agonism Protects Mice from Radiation Pneumonitis and Pulmonary Fibrosis

Wang, Zhi-Dong,Qiao, Yu-Lei,Tian, Xi-Feng,Zhang, Xue-Qing,Zhou, Shi-Xiang,Liu, Hai-Xiang,Chen, Ying Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

Radiation pneumonitis and pulmonary fibrosis are the main complications with radiotherapy for thoracic neoplasms, directly limiting the efficient dose in clinical application and currently there are few medicines that effectively function as radioprotectants. However, a TLR5 agonist, CBLB502, was confirmed to have protective efficacy against hematopoietic and gastrointestinal radiation syndromes in mice and primates. This study points to a new direction for protection against thoracic radiation-induced pulmonary syndromes and skin injury by CBLB502. We utilized the TUNEL assay, pathological analysis and immunohistochemistry to obtain evidence thatCBLB502 could alleviate the occurrence of radiation pneumonitis and pulmonary fibrosis as well as radiation-induced skin injury. It may thus play a promising role in facilitating clinical radiotherapy of thoracic neoplasms.

Optimal Tracking Control for Discrete-time Systems with Multiple Input Delays under Sinusoidal Disturbances

Shi-Yuan Han,Yue-Hui Chen,Dong Wang,Gong-You Tang,Xi-Xin Yang 제어·로봇·시스템학회 2015 International Journal of Control, Automation, and Vol.13 No.2

This study researches the tracking control problem for discrete-time systems with multiple input delays affected by sinusoidal disturbances. This study is organized around the expression of sinusoidal and disturbances and the delay-free transformation. First, based on the periodic characteristic of the sinusoidal disturbance, the sinusoidal disturbances are considered as the output of an exosystem. By proposing a discrete variable transformation, the discrete-time system with multiple input delays and the quadratic performance index are transformed into equivalent delay-free ones. Then, by constructing an augmented system that comprises the states of the exosystems of sinusoidal disturbances, the reference input, and the delay-free transformation systems, the original tracking problem is transformed into the optimal tracking problem for a delay-free system with respect to the simplified performance index. The optimal tracking control (OTC) law is obtained from Riccati and Stein equations. The existent and uniqueness of the optimal control law is proved. A reduced-order observer is constructed to solve the problem of physically realizable for the items of the reference input and sinusoidal disturbances. Finally, the feasibility and effectiveness of the proposed approaches are validated by numerical examples.

Evaluation on Nutritional Value of Field Crickets as a Poultry Feedstuff

Wang, Dun,Zhai, Shao Wei,Zhang, Chuan Xi,Bai, Yao Yu,An, Shi Heng,Xu, Ying Nan Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.5

The proximate analysis, amino acid content and true amino acid digestibility and TMEn for poultry of adult Field crickets Gryllus testaceus Walker, were investigated. The insect was also used as partial replacement of protein supplements in the broiler diet on an equal CP percentage and TMEn basis. The results indicated that the adult insect contained: crude protein 58.3%; fat 10.3%, chitin 8.7% and ash 2.96% on dry matter basis, respectively. The total amounts of methionine, cystine and lysine in the Field crickets were 1.93%, 1.01% and 4.79%, respectively, and their true digestibility coefficients, determined in cecectomized roosters, were 94.1%, 85% and 96%, respectively. The TMEn of this insect meal was 2,960 kcal/kg determined in cecectomized roosters. When cornsoybean meal diets were formulated on an equal CP percentage and TMEn basis, up to 15% Field cricket could replace control diet without any adverse affects on broiler weight gain, feed intake or gain:feed ratio from 8 to 20 d posthatching.

Predicting standard-dose PET image from low-dose PET and multimodal MR images using mapping-based sparse representation

Wang, Yan,Zhang, Pei,An, Le,Ma, Guangkai,Kang, Jiayin,Shi, Feng,Wu, Xi,Zhou, Jiliu,Lalush, David S,Lin, Weili,Shen, Dinggang IOP 2016 Physics in medicine & biology Vol.61 No.2

<P>Positron emission tomography (PET) has been widely used in clinical diagnosis for diseases and disorders. To obtain high-quality PET images requires a standard-dose radionuclide (tracer) injection into the human body, which inevitably increases risk of radiation exposure. One possible solution to this problem is to predict the standard-dose PET image from its low-dose counterpart and its corresponding multimodal magnetic resonance (MR) images. Inspired by the success of patch-based sparse representation (SR) in super-resolution image reconstruction, we propose a mapping-based SR (<I>m</I>-SR) framework for standard-dose PET image prediction. Compared with the conventional patch-based SR, our method uses a mapping strategy to ensure that the sparse coefficients, estimated from the multimodal MR images and low-dose PET image, can be applied directly to the prediction of standard-dose PET image. As the mapping between multimodal MR images (or low-dose PET image) and standard-dose PET images can be particularly complex, one step of mapping is often insufficient. To this end, an incremental refinement framework is therefore proposed. Specifically, the <I>predicted</I> standard-dose PET image is further mapped to the <I>target</I> standard-dose PET image, and then the SR is performed again to predict a new standard-dose PET image. This procedure can be repeated for prediction refinement of the iterations. Also, a patch selection based dictionary construction method is further used to speed up the prediction process. The proposed method is validated on a human brain dataset. The experimental results show that our method can outperform benchmark methods in both qualitative and quantitative measures.</P>

The role of PDIA3 in myogenesis during muscle regeneration

Xi Peng,Chao Wang,Yuanjiao Zhu,Dan Wu,Zien Wang,Xiaoli Xu,Yan Shi,Gang Yang,Yongming Yu 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

Beta 3 (β3) integrin plays an important role in the initiation of myogenesis in adult muscle. Protein disulfide isomerases (PDIs) can activate β3 integrin in various cells to promote cell migration, adhesion and fusion. However, the effect of PDIs on myogenesis during muscle regeneration has not been elucidated. Here, we report that PDIA3 expression is induced in regenerating myofibers. The inhibition of PDIA3 in muscle injuries in mice disrupts myoblast differentiation, impairs muscle regeneration, and ultimately aggravates muscle damage. Moreover, PDIA3 expression is upregulated and observed on the cell surfaces of myoblasts during differentiation and fusion. The inhibition of extracellular PDIA3 with an anti-PDIA3 monoclonal antibody attenuates β3 integrin/AKT/mTOR signal activity, inhibits myoblast differentiation, and blocks the fusion of myoblasts. Thus, PDIA3 may be a mediator of myoblast differentiation and fusion during muscle regeneration.