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      • Poster Session : PS 0064 ; Cardiology : Epidemiology and Clinical Aspects of Infectious Endocarditis in a Tertiary Hospital

        ( Yasser Hessein Abdou ),( Nancy Giovanna Uribe Heredia ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Introduction and objectives: Infective endocarditis (IE) is a microbial infection of intracardiac structures, their importance derives from its high risk of mortality. The aim of this study is to describe the epidemiological and clinical characteristics of infective endocarditis in a population sample. Methods: A descriptive study of all patients over 18 years who met the modifi ed Duke criteria for the diagnosis of IE between 2006-2010 in our hospital. Were included. Results: Of the 27 cases, 77.8% (21 cases) have defi nitive IE and 22.2%(6 cases) have possible EI, mean age 62.5+15 years, with a minimum of 18 years and a maximum of 81 years. 44.4% (12 cases) were older than 70 years and 55.6% under 70 years (15 cases). 66.7% were male (18 cases) and 33.3% (9 cases) are women. Preexisting heart disease was rheumatic type (30%), degenerative (30%),congenital heart disease (11%) and previous EI(4%). 67% of the affected valves were native and 33% were prosthetic valve (22% mechanical and 11% organic). The affected valve was the mitral, aortic, or both in 30%, 41% and 10% respectively. The high degree of valvular regurgitation was mild, moderate and severe in 15%, 19% and 33%, respectively, in 33% there was no echocardiographic evidence of valvular insuffi ciency. In 88.9% of cases, serum cultures were positive and in 11.1% were negative. In the group of elderly (over 70 years) the most frequent germ were the coagulase-negative group with 6 cases (50%) and the under 70 group predominated catalase negative bacteria(60%), this difference was statistically signifi cant (p <0.05). Conclusions: Having had a past history of EI, the presence of an embolic event during the course of the infection and having a metal valve prosthesis are associated with increased mortality. The overall mortality rate was 14.8%

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