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      • Poster Session : PS 0064 ; Cardiology : Epidemiology and Clinical Aspects of Infectious Endocarditis in a Tertiary Hospital

        ( Yasser Hessein Abdou ),( Nancy Giovanna Uribe Heredia ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Introduction and objectives: Infective endocarditis (IE) is a microbial infection of intracardiac structures, their importance derives from its high risk of mortality. The aim of this study is to describe the epidemiological and clinical characteristics of infective endocarditis in a population sample. Methods: A descriptive study of all patients over 18 years who met the modifi ed Duke criteria for the diagnosis of IE between 2006-2010 in our hospital. Were included. Results: Of the 27 cases, 77.8% (21 cases) have defi nitive IE and 22.2%(6 cases) have possible EI, mean age 62.5+15 years, with a minimum of 18 years and a maximum of 81 years. 44.4% (12 cases) were older than 70 years and 55.6% under 70 years (15 cases). 66.7% were male (18 cases) and 33.3% (9 cases) are women. Preexisting heart disease was rheumatic type (30%), degenerative (30%),congenital heart disease (11%) and previous EI(4%). 67% of the affected valves were native and 33% were prosthetic valve (22% mechanical and 11% organic). The affected valve was the mitral, aortic, or both in 30%, 41% and 10% respectively. The high degree of valvular regurgitation was mild, moderate and severe in 15%, 19% and 33%, respectively, in 33% there was no echocardiographic evidence of valvular insuffi ciency. In 88.9% of cases, serum cultures were positive and in 11.1% were negative. In the group of elderly (over 70 years) the most frequent germ were the coagulase-negative group with 6 cases (50%) and the under 70 group predominated catalase negative bacteria(60%), this difference was statistically signifi cant (p <0.05). Conclusions: Having had a past history of EI, the presence of an embolic event during the course of the infection and having a metal valve prosthesis are associated with increased mortality. The overall mortality rate was 14.8%

      • Poster Session : PS 0153 ; Diabetes : Basal-Bolus Insulin Regimens and a Discharge-Strategy in Hospitalized Patients with Type 2 Diabetes Can Improve and Maintaining Control Glucemic During Several Years

        ( Pedro Reales Figueroa ),( Yasser Hessein Abdou ),( Maria Martin Toledano Lucas ),( Ibrahim Hamad ),( Adrian Ruiz Fernandez ),( Juan Velasco Franco ),( Marta Salas Cabanas ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Aims: Current guidelines recommend the use of a basal-bolus insulin regimen in hospitalized patients with hyperglycemia or type 2 DM. In addition a simple strategy facilitating the reconciliation of medication on discharge can improve glycemic control post-discharge. With our study we want to test whether this better glycemic control is maintained over time. Methods: Our study is a prospective and observational study during routine clinical practice. It has been held in an Department of Internal Medicine during hospitalization, with follow-up visit at 3 months after discharge and followed up for 3 years. Study patients (30) were treated with a regimen of basal-bolus insulin during hospitalization and an adjustment of their antidiabetic treatment at discharge. As a control group we included patients(30) hospitalized with similar characteristics, treated with other regimen of insulin or oral antidiabetic agents and to which either no treatment adjustment is recommended at discharge. A follow-up to all patients at 3 months after discharge and again after 3 years I realize. Results: Comparing the study group with the control group we found no differences in baseline HbA1c (8,52%±0,81 vs 8,61%±0.72; p:0,652), age (67,7±3,76 vs 67,8±3,71; p:0,86), sex (16 male vs 17 mal) and BMI (30,33±1,62 Kg/m2 vs 30,41±1,63 Kg/m2). Compared with baseline, the HbA1c at 3 months after discharge is lowe r(7,51%±0.81 vs 8,52%±0,81;p:0,001) and 3 years after discharge also remains lower(7,81%±0,81vs8,52%±0,81; p:0,013). Compared with control subjects, patients included in study have lower HbA1c at 3 months after discharge (7,51%±0,81 vs 8,71% ± 0,81:p:0,004) and lower HbA1c at 3 years after discharge (7,81%±0,81 vs 8,91%±0,81; p:0,002). Conclusion: This study confi rm that protocols to manage hyperglycemia with basal-bolus insulin regimens are also feasible and effective in routine clinical practice, and demonstrate that a simple strategy facilitating the reconciliation of medication on discharge can improve glycemic control post-discharge, that remains after 3 years or follow.

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