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Miguel Vazquez-Velasco,Laura Gonzalez-Torres,Rosa A. Garcıa-Fernandez,Marıa Teresa Mendez,Sara Bastida,Juana Benedı,Marıa Jose Gonzalez-Munoz,Francisco J. Sanchez-Muniz 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.6
Glucomannan-enriched squid surimi improves cholesterolemia and liver antioxidant status. The effect of squid surimi enriched with glucomannan or glucomannan plus spirulina on liver and heart structures and cell damage markers was tested in fa/fa rats fed highly saturated-hyper-energetic diets. Animals were fed 70% AIN-93M rodent diet plus six versions of 30% squid surimi for 7 weeks: control (C), glucomannan (G), and glucomannan plus spirulina (GS). The cholesterol-control (HC), cholesterol-glucomannan (HG), and cholesterol-glucomannan plus spirulina (HGS) groups were given similar diets that were enriched with 2% cholesterol and 0.4% cholic acid. G and GS diets versus C diet significantly inhibited weight gain and lowered plasma alanine aminotransferase and aspartate aminotransferase, liver steatosis, lipogranulomas, and total inflammation and alteration scores. The hypercholesterolemic agent significantly increased the harmful effects of the C diet. Liver weight, the hepatosomatic index, all damage markers, and total histological scoring rose for HC versus C (at least P < .05). The addition of glucomannan (HG vs. HC) improved these biomarkers, and non-additional effects from spirulina were observed except for the total liver alteration score. In conclusion, glucomannan and glucomannan plus spirulina blocked the highly saturated-hyper-energetic diet negative effects both with and without added cholesterol. Results suggest the usefulness of including these functional ingredients in fish products.
Prediction-observer Scheme for Linear Systems with Input-output Time-delay
Varinia Fragoso-Rubio,Martín Velasco-Villa,Miguel A. Hernández-Pérez,Basilio del Muro-Cuéllar,Juan Francisco Márquez-Rubio 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.8
This work deals with the prediction and control problems associated with a class of linear systems with time-delay at the input-output path. A general prediction observer scheme that estimates the future value of the delayed system from the output is proposed. Later, a full-information predictor-observer is introduced and the convergence of the estimated future values is formally proven for a time-delay τ of any size by increasing the dimension of the proposed predictor-observer. The estimated future state is used to design a feedback law that compensates the delay effects on the original system. The performance of the prediction-observation control strategy is shown by means of numerical simulations. Thus, it is illustrated that the performance of the proposed full-information predictor-observer is improved with respect to the sequential sub-predictors previously presented in the literature.
Adriana R. Schultz Moreira,Raúl Olivero-David,Miguel Vázquez-Velasco,Laura González-Torres,Juana Benedí,Sara Bastida,Francisco J. Sánchez-Muniz 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.8
There is a general assumption that seaweeds are hypocholesterolemics and antioxidants. However, controversial results suggest specific properties for each individual alga. This study aims to assess the effect of including Sea Spaghetti alga (S) in a restructured-pork (RP) diet, both enriched and not enriched with dietary cholesterol, on arylesterase (AE) activity and lipoprotein concentration and composition of Wistar rats. Four groups of 10 growing male Wistar rats were each fed a mix of 85% AIN-93M diet and 15% freeze-dried RP for 5 weeks. The control group (C) consumed control RP-C; the S group consumed RP-S with 5% seaweeds; the Chol-C group consumed the C diet but enriched with cholesterol (2.43%) and cholic acid (0.49%); the Chol-S group consumed the S diet but enriched with cholesterol and cholic acid. AE activity was five times higher (P < .01) in S compared with C rats, but three times lower in Chol-S compared with Chol-C rats (P < .01). The Chol-C diet induced hypercholesterolemia but reduced triglycerides (TG), giving rise to the presence of very low-density lipoprotein (VLDL) that was enriched in cholesterol. The Chol-S diet partially blocked (P < .001) the hypercholesterolemic induction of the Chol-C diet, and reduced TG levels (P < .05) with respect to S rats. The cholesterol supplementation increased total cholesterol, VLDL-cholesterol, and intermediate-density lipoprotein + LDL-cholesterol (IDL + LDL)-cholesterol (P < .001) in Chol-C rats, but the effect was lower in the Chol-S diet. In conclusion, RP-S increases the antioxidant capacity within a noncholesterol enriched diet while improving the lipoprotein profile within a cholesterol-enriched diet.
A Novel Approach to Trojan Horse Detection in Mobile Phones Messaging and Bluetooth Services
( Juan A. Ortega ),( Daniel Fuentes ),( Juan A. Lvarez ),( Luis Gonzalez-abril ),( Francisco Velasco ) 한국인터넷정보학회 2011 KSII Transactions on Internet and Information Syst Vol.5 No.8
A method to detect Trojan horses in messaging and Bluetooth in mobile phones by means of monitoring the events produced by the infections is presented in this paper. The structure of the detection approach is split into two modules: the first is the Monitoring module which controls connection requests and sent/received files, and the second is the Graphical User module which shows messages and, under suspicious situations, reports the user about a possible malware. Prototypes have been implemented on different mobile operating systems to test its feasibility on real cellphone malware. Experimental results are shown to be promising since this approach effectively detects various known malware.