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류마치양 관절염 및 퇴행성관절염에 대한 Piroxicam의 사용경험
윤승호(Sung Ho Youn),이광진(Kwang Zin Lee),안상노(Sang No Ahn) 대한약리학회 1979 대한약리학잡지 Vol.15 No.1
Piroxicam is known to be a new nonsteroidal anti-inflammatory drug which has anti-inflammatory, antiedema, antigranuloma and analgesic activities through the mechanism of inhibition of prostaglandin synthetase. Clinical survey for piroxicam was carried cut on 40 cases of rheumatoid arthritis and 30 cases of degenerative arthritis who visited University Hospital from Feb. to June, 1979. Following results could be obtained: 1) In rheumatoid and degenerative arthritis, the effect of piroxicam was significant in decrease of joint pain, shortening of duration of morning stiffness, decrease in number of swollen joints, improvement of joint stiffness, decrease of E.S.R., increase of mean grip strength and decrease of articular index. 2) Side effects, almost all in G-I troubles were encountered in 6 cases in 40 cases of rheumatoid arthritis and 4 cases in 30 cases of degenerative arthritis.
정형외과 영역에 있어서 Diclofenac sodium의 임상적 연구
이광진,이준규,안상로,정태성,임상덕 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1
This study was designed to research the clinical efficacy and tolerance of Diclofenac sodium, a potent inhibitor of prosta-glandin synthetase. Total 53 cases of painful condition in orthopaedic field were treated with Diclofenac sodium, available for intramuscular injection, in department of orthopaedic surgery of Chungnam National University Hospital from Nov. , 1986 to Jan. , 1987. Among 53 cases of painful condition, The most common condition was rheumatoid arthritis and osteoarthritis (33cases; 60. 3%), followed by sprain and strain(llcases; 20. 8%), postoperative state(7cases; 13.2%), and others(3cases 5.7%). There was no predilection in age and sex distribution. At thirty minutes after the injection, 46/53patients treated with Diclofenac sodium had complete 31(58.5%) or partial 15(28..3%) relief of pain. Side effects were mild and transient. It is concluded that intramuscular injection of Diclofenac sodium is effective in treatment of pain due to operative intervention & various disease in orthopaedic field.
골 및 관절염과 혈청학적 및 혈구의 세포 화학적 변화에 관한 연구
배대경,이광진,이한구,한문식 최신의학사 1972 最新醫學 Vol.15 No.5
Statistical analysis of laboratory findings in orthopedic diseases was studied. Pathologicallyo confirmed cases and outpatients were included in this study. The purpose of this article is to find diagnostic significance of laboratory findings.