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      저자 : 황대룡 ( Dae Ryong Hwang ) (검색결과 2 건)
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        행인의 알레르기 천식 효과에 대한 연구

        황대룡 ( Dae Ryong Hwang ),강영성 ( Young Sung Kang ),김성수 ( Sung Soo Kim ),김대한 ( Dae Han Kim ),신민교 ( Min Kyo Shin ),송호준 ( Ho Joon Song ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.2

        N/A Objective : To evaluate the effect of Semen Armeniaceae Amarum (SAA) on allergy, studies were done experimentally. Methods : After induction of allergic inflammation asthma by treatment of ovalbumin, water extract from SAA were taken orally for five successive days on mice respectively. We were measured in BALF, serum IgE, FCA on the biochemical change associated with allergy. Results : In the total cell of BALF, the SAA extract 48Omg/kg treated group was significantly reduced compared to control group and the reduction of eosinophil showed significantly at concentration of 240, 48Omg/kg. The SAA extract (480mg/kg) group was significantly decreased compared to control group on IgE antibody formation. SAA dose-dependently also significantly inhibited to passive cutaneous anaphylaxis(PCA) activated by anti - dinitropheny 1 (DNP) IgE. Conclusions : These results indicate that Semen Armeniaceae Amarum showed benefical effect on the allergic asthma.

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        알레르기에 대한 미역줄나무의 물 추출물의 효과

        변종호 ( Jong Ho Byun ),강영성 ( Young Sung Kang ),김성수 ( Sung Soo Kim ),김대한 ( Dae Han Kim ),황대룡 ( Dae Ryong Hwang ),신민교 ( Min Kyo Shin ),송호준 ( Ho Joon Song ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.2

        N/A Objective : To evaluate effect of allergy by Tripterygiwn regelii (TR), the biochemical changes associated with allergy were measured in BALF. serum splenocyte and lung of mice. Methods : After induction of allergic inflammation asthma by treatment of ovalbumine, water extracts from stem and leaf (SL) or flower (FL) of TR were taken orally for five successive days on mice, respectively. Result : In the total cell of BALF. the SL-TR extract (lCKhwk, h.w)-treated group was significantly reduced compared to control level and the reduction of eosinophil showed significantly at concentraton of 360 and loo0 dks, b.w. On the other hand, substantial decrease in IgE antibody formation was significantly observed by administration with SL-TR extract, whereas IgGZa was not affected. IgCl antibody formation appeared to be decreased inserum from SL-TR treated mice(l000 mg/kg, b.w). The content of IL-4 exhibited physiological role in splenocyte and lung was significantly reduced in the examined group compared to that of control after treatment of SL-TR extract(l@X/kg, b.w). In the case of IL-5, however, it was significantly reduced by FL-TR extract. In addition, IL-5 content in splenocyte was significantly reduced at concentration of 360 and loo0 d k g . b.w. by SL-TR dose, respxtively, and that of lung was significantly reduced dose-dewndently(l20, 360 and 1000mp/kg, b.w). Cnnclusion : It could be conduded that TripteTygiwn regelii showed beneficial effect on the allergic asthma and especially, its leaf and stem is more effective than flower.

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