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      • KCI등재후보

        간경변증 식도정맥류에 대한 내시경적 경화요법의 임상효과와 장기 예후

        홍득민(Duk Min Hong),김두섭(Doo Sub Kim),윤중근(Jung Kun Yoon),김종인(Jong In Kim),이성주(Sung Joo Lee) 대한내과학회 1993 대한내과학회지 Vol.45 No.1

        N/A Background: Endoscopic injection sclerotherapy (EIS) in cirrhotic patients was evaluated in comparison with patients not undergoing EIS. Methods: The subjects were 85 patients with EIS (EIS cases) and 106 patients without EIS (non-EIS cases) of liver cirrosis (LC) with or without hepatocellular carcinoma (HCC) in the same period. All cases had Stage III esophageal varices Results: The results were as follows 1) Urgent hemostatic rate in EIS cases was significantly higher than that in non-EIS cases. 2) The cumu1ative survival probability in EIS cases was significantly higher than that in non-EIS cases. 3) The cumulative survival probability (in EIS cases) was significantly higher in complete varix disappearance, before bleeding in recurent varix, EO-AS combination therapy. Conclusion: The survival rate was significantly improved in stage III esophageal varices by preventive endoscopic injection sclerotherapy (ELS).

      • KCI등재후보

        세침 폐생검 세포검사의 진단적 의의

        김영철(Young Chol Kim),박용주(Yong Ju Park),김두섭(Doo Sub Kim),홍득민(Duk Min Hong),양윤식(Yoon Shig Yang),심원보(Won Bo Shim),윤중근(Jung Geun Yoon),김종인(Jong In Kim),이성주(Seong Joo Lee),이태원(Tae Won Lee) 대한내과학회 1991 대한내과학회지 Vol.41 No.6

        N/A Seventy-five patients with either pulmonary nodules or masses that could not be confirmed with sputum examination or bronchoscopic examination underwent transthoracic fineneedle aspiration with 22 or 23 gauze needles under fluoroscopy for cytologic diagnosis. There were 51 men and 24 women, and the age range was 43-78 years old. The lesion distribution and sizes were as follow: 48 cases in the right lung, 2l cases in the left lung, 23 cases under 4 cm in size, and 52 cases over 4 cm in size. There were no meaningful correlations in lesion size or site with malignant or benign cytologic findings. Among the 46 malignant cases squamous cell carcinoma was 32 cases, large cell carcinoma 5 cases, small cell carcinoma 4cases, lymphoma 3 cases, and bronchioalveolar carcinoma 2 cases. Among the other cases, pulmonary tuberculosis was. 11 cases and lung abcess 3 cases. Among the 49 cases proven malignant after operation or follow-up by now, 46 cases were malignant at fine- needle aspiration biopsy cytology (sensitivity 93.9%), and among the 23 cases proven benign after follow up, all showed no malignancy by fine-needle aspiration biopsy cytology (specificity 100%). Three cases failed in the follow-up due to various causes. In the benign cases, there were some who had difficulty in being diagnosed with this procedure alone, but we were helped a great deal in differentiating malignancies by this procedure. Complications were minimal, but 5 cases of pneumoth-orax occurred, and 2 cases among these needed closed thoracotomy and soon improved. In conclusion, transthoracic fine-needle aspiration biopsy cytology is very helpful in diagnosing patients with lung nodules or masses that failed to be confirmed with sputum examination or bronchoscopic procedure and in differentiating a malignant state from a benign one, with minimal complications. So, active clinical trial of this procedure is recommended.

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