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허부 ( Boo Hur ),이병렬 ( Byung Ryul Lee ),임윤경 ( Yun Kyoung Yim ) 대한경락경혈학회 2008 Korean Journal of Acupuncture Vol.25 No.2
Objectives and Methods: The purpose of this study was to observe the effects of acupuncture and electro-acupuncture (EA) at PC6 on intestinal motility in rats. We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with Loperamide in rat, and carried out acupuncture with needle retained (NR), Low frequency (2 Hz) EA and high frequency (100 Hz) EA at PC6 before or after the administration of carbachol or Loperamide. The charcoal travel rate was measured to evaluate the intestinal motility. Results: 1. NR showed no significant influences on intestinal motility of rat in normal state. While, 2 Hz EA and 100 Hz EA at PC6 significantly increased the intestinal motility of rat in normal state. 2. All of the pre-treatment and post-treatment of NR, 2 Hz EA and 100 Hz EA at PC6 showed no significant effects on intestinal motility of rat which was over-activated with carbachol. 3. Both pre-treatment and post-treatment of NR significantly increased intestinal motility in rat which was suppressed with Loperamide. 4. Pre-treatment of 2 Hz EA and post-treatment of 100 Hz EA significantly increased intestinal motility in rat which was suppressed with Loperamide. Conclusions: These results suggest that acupuncture (NR) and EA on PC6 have preventive and therapeutic effect on suppressed intestinal motility, and NR may be more effective than EA in that condition.
음곡 차전자 약침이 LPS로 유도된 흰쥐의 신장염에 미치는 영향
박병문 ( Byong Mun Park ),허부 ( Boo Hur ),임윤경 ( Yun Kyoung Yim ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.2
Objective: This study aimed to evaluate the effects of Plantaginis Semen herbal-acupuncture (PS-HA) at KI10 (Umgok) on nephritis induced by lipopolysaccharide (LPS) in rat. Methods: The authors performed several experimental items including measurements of urinary volume, WBC in blood, BUN, creatine, TNF-α, CINC-1 in serum, creatinine, total protein in urine, TNF-α, MPO in kidney and histological analysis of renal tissue. Results: PS-HA at KI10 significantly reduced WBC in blood, BUN, TNF-α in serum of LPS-stimulated rats. PS-HA at KI10 significantly increased urinary volume in LPS-stimulated rats. And PS-HA at KI10 significantly reduced MPO in kidney of LPS-stimulated rats. Conclusion: Taken together, PS-HA at KI10 has a therapeutic effect on nephritis in LPS-stimulated rat. Therefore, it is suggested that PS-HA at KI10 may be an useful therapeutics for nephritis in clinical field.