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Development of Two Hexaplex Systems with X-STR Loci and Their Allele Frequencies in Koreans
이경룡,한면수,조범호,박선화,허기범,정기화 한국유전학회 2008 Genes & Genomics Vol.30 No.1
X-chromosomal short tandem repeat (X-STR) markers can be used to determine paternity in deficiency paternity cases with a female child(s) and in other kinship tests. In the present ncludes DXS6789, DXS6810, DXS7132, GATA172D05, DXS7423, and ARA, while the other set includes GATA165B12, DXS981, DXS6797, DXS9898, DXS8377, and DXS7424. These STR loci were genotyped in a Korean population (149 males and 121 females), and the alele frequency was obtained using the established multiplex PCR reactions and an automatic sequenloci in female samples deviated from Hardy-Weinberg equilibrium. The combined probabilities of match (PM) calculated from 12 X-STR loci were 2.04 × 10-12 in females and 7.46 × 10-8 in males, which is highly informative. The high polymorphism of these X-STRs indicated the stems will be used directly to analyze forensic cases.