치료의 증진을 위한 당뇨전문약사의 필요성

박인경(In Kyung Park),이수영(Soo Young Lee),윤지연(Jee Yeon Yun),한옥연(Ok Youn Han),이보름(Bo Reum Lee),장제관(Je Kwan Jang),나현오(Hyen Oh La),임성실(Sung Cil Lim) 대한약학회 2009 약학회지 Vol.53 No.4

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia and abnormalities in carbohydrate, fat, and protein metabolism which is resulting chronic microvascular, macrovascular, and neuropathic complications. Therefore, correct and consistent educations for pharmacotherapy is important and especially drug consultation by the specialty pharmacist of diabetic pharmacotherapy is necessary for all diabetic patients. The purpose of this study is to evaluate the necessity of the specialty pharmacist of diabetic pharmacotherapy and this study was performed from June 31th, 2008 to October 9th, 2008 in Kangnam St. Mary’s Hospital, Seoul, S. Korea throughout the questionnaire and evaluated the total 68 patients who were participating the multidisciplinary diabetes team programs. We evaluated the patient characteristics (n=68), learning status (difficulty 70.4%), wanted further education (68.3%) and preference of educator (pharmacist 46%) after finishing team teaching by multidisciplinary diabetes team program. In conclusion, many diabetic patients(80.3%) wanted individual and further drug consultation by the pharmacists who are specialized in the diabetes individually and they are needed.

다발성 골수종 환자에서 Lenalidomide와 Thalidomide에 의한 말초신경병증 발병 비교 연구

이소희(So Hee Lee),우지윤(Ji Yun Woo),황보신이(Shin Yi Hwangbo),민미나(Mi Na Min),한옥연(Ok Youn Han) 대한약학회 2020 약학회지 Vol.64 No.6

Lenalidomide (LD) inhibits angiogenesis and exerts immunosuppressive effects. It has been used to treatmultiple myeloma and is known to show positive differences in side effects compared to thalidomide (TD). Peripheralneuropathy, one of the most common complications of TD, has been reported to be less frequent with LD treatment. However, no local study has been conducted to compare the incidence of peripheral neuropathy associated with TD andLD administration. Therefore, this study was performed to investigate the appearance, aggravation, or improvement ofperipheral neuropathy and the relevant risk factors in patients treated with LD and TD. The electronic medical records of169 patients with multiple myeloma who had been treated with LD and TD in a tertiary hospital between March 2014and March 2015 were retrospectively reviewed. There were 85 patients in the LD group and 84 patients in the TD groupfor the final analysis. An increase in severity of peripheral neuropathy after treatment was observed in 2.4% and 19.1%of patients in the LD and TD groups, respectively (p<0.001). Six patients in the TD group showed two or more increasesin grade. In total, 48.2% in the LD group and 10.7% in the TD group (p<0.001) continued chemotherapy without anyaggravation of peripheral neuropathy. The patients treated with LD showed less increase in severity of peripheralneuropathy compared with those treated with TD. A significant difference was observed between the groups in thepercentage of patients who continued treatment without peripheral neuropathy aggravation.

Bisphosphonate

한옥연 약업신문사 2000 의약정보 Vol.2000 No.4

Proton-pump 저해제

한옥연 약업신문사 2000 의약정보 Vol.2000 No.2

Angiotensin Ⅱ Receptor Antagonist

한옥연 약업신문사 2000 의약정보 Vol.2000 No.1

ACEI : Angiotensin Converting Enzyme Inhibitor

한옥연 약업신문사 1999 의약정보 Vol.1999 No.12

Cox-2 Inhibitor

한옥연 약업신문사 2000 의약정보 Vol.2000 No.5

고지혈증 치료제

한옥연 약업신문사 2000 의약정보 Vol.2000 No.3

3차진료기관 외래약국 투약대기시간에 영향을 주는 요인

박하영,한옥연,나현오 한국의료QA학회 1994 한국의료질향상학회지 Vol.1 No.2

Background: The number of outpatients visiting large university teaching hospitals has increased drastically with the introduction of a nationwide health care insurcnce in 1989 and the improvement of the socio-economic status of the population. This resulted in long waiting times for services, parlicularly prescribed drugs, which have been patients chief complaints. Hospitals have tried to solve the problem with limited success because their approach lacked comprehansive research. The objective of this study is to investigate associations between waiting times and variables defining a total work system. Methods: Data for the outpatient pharmacy department in a tertiary care university teaching hospital located in Seoul was analyzed to achieve the study objective. Associations of pharmacy system variables -work load, work force, pharmacist work schedule, machine problems, and inventory control- with mean and 99th percentile of waiting times were examined by the hierarchical stepwise regression method. Day was a unit of the analyses. Results: The regression models explained 65.8% of variance in the mean waiting time and 61.34% in the 99th percentile of waiting times. The break-down of the printer for drug envelops, Automatic Tablet Counters (ATCs), and main compute system lasted longer than 30 minutes increased the mean for 7.7 minutes, 4.5 minutes, and 7.0 minutes, respectively and the 99th percentile for 14.8 minutes, 9.0 minutes, and 15.7 minutes, respectively. Concerning the work force, study results showed that there were significant differences in the productivity of pharmacists with work experience more than three years, one to three years, and less than one year, and showed that peak time aid work by pharmacists at job assignments other than the outpatient pharmacy, part-time pharmacists, and the installation of ATCs were effective in reducing waiting times. Finally, study findings indicated that the operational policy of work assignment and rotation schedule, supply and inventory of drugs at work tables, and readiness for undisrupted work during the work hours could have a significant effect on waiting times. Conclusion: The study results indicated that efforts to reduce waiting times for prescribed drugs should be geared toward every components of the pharmacy work system ranging from work schedule of pharmacists and supply of drugs at work tables. These findings should provide hospital managers with right directions in battling the problem.

강남성모병원에서 DRG 지불제도 시범 실시 전후의 약물사용 분석

양승희,이주영,임양순,한옥연,홍경자,나현오 한국병원약사회 2000 병원약사회지 Vol.17 No.1

Diagnosis Related Group (DRG) payment system has been applied to 5 diagnosis group (Lens procedure, Tonsilectomy and/or Adenoidectomy, Cesarean section, Vaginal delivery) at Kang-Nam St. Mary's hospital since Feb. 1998. To analyze the medication use and its effect, of this system, we reviewed the medical records of total 586 patients who had been hospitalized with the above diagnosis during Aug. 1997, the Doings-Based Group (DBG) and Aug. 1998, the DRG. We compared the total cost, average length of hospital stay, cost of medications including the antibiotics, and the therapeutic effects by defining the cause of prolonged length of hospital stay between the two groups. As a result, the total cost was decreased in DRG mainly by shortening the length of hospital stay. The total medication and the antibiotic costs were decreased only in the Cesarean section and in vaginal delivery group of the DRG. But the ratio of the antibiotic cost to the total medication cost was decreased in all DRG. We found no differences of the therapeutic effects in both groups and no case of motality nor re-operation. In conclusion, the total medication cost were increased or decreased in the DRG comparing with the DBG without therapeutic differences. But in pharmacoeconomic point of view, we should try to make a medication guideline since there has been a tendency to use more recent and expensive medications. For this purpose active participation of the pharmacist in a critical pathway team is imperative for the patients.