http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
장민규(Min-Gyu Jang),이철희(Chul-Hee Lee),손정우(Jung Woo Sohn),한영민(Young-Min Han),최승복(Seung-Bok Choi) 한국트라이볼로지학회 2008 한국트라이볼로지학회 학술대회 Vol.2008 No.11
In this work, durability characteristics of electrorheological (ER) fluid for damper application are experimentally investigated. ER fluid is prepared by using phosphorated starch particles and silicone oil. The field-dependent Bingham characteristics and response time for the proposed ER fluids are experimentally obtained. Experimental apparatus of durability test for ER fluid is established with cylindrical ER cylinder for mid-sized passenger vehicle. In order to evaluate the durability characteristics of ER fluid as a function of time, damping force and temperature variations are measured until one million cycles. After durability test, Bingham characteristics and response time of ER fluid are measured and compared to the initial properties. Microscopic pictures of ER fluid are taken to validate the changes of properties. The results indicate that the ER fluid can be commercially utilized in vehicle damper system with its durability performance. Moreover, the understanding of durability characteristics is essential to predict the service life ofER fluid as well as to design its applications.
이철희(Chul-Hee Lee),장민규(Min-Gyu Jang),손정우(Jung Woo Sohn),한영민(Young-Min Han),최승복(Seung-Bok Choi) 한국트라이볼로지학회 2009 한국윤활학회지(윤활학회지) Vol.25 No.5
In this work, durability characteristics of electrorheological (ER) fluid for damper application are experimentally investigated. ER fluid is prepared by using phosphorated starch particles and silicone oil. The field-dependent Bingham characteristics and response time for the proposed ER fluids are experimentally obtained. Experimental apparatus of durability test for ER fluid is established with cylindrical ER cylinder for mid-sized passenger vehicle. In order to evaluate the durability characteristics of ER fluid as a function of time, damping force and temperature variations are measured until one million cycles. After durability test, Bingham characteristics and response time of ER fluid are measured and compared to the initial properties. Microscopic pictures of ER fluid are taken to validate the changes of properties. The results indicate that the ER fluid can be commercially utilized in vehicle damper system with its durability performance. Moreover, the understanding of durability characteristics is essential to predict the service life of ER fluid as well as to design its applications.
기초 : 악성신경교종의 세포고사체로 감작시킨 수지상세포에 의해 유도된 종양특이적 T 림프구의 HLA Type에 따른 세포독성
박익성 ( Ik Seong Park ),정동섭 ( Dong Sup Chung ),한영민 ( Young Min Han ),장경술 ( Kyung Sool Jang ),김종태 ( Jong Tae Kim ),박영섭 ( Young Sup Park ) 대한뇌종양학회 2008 대한뇌종양학회지 Vol.7 No.2
Objective:The purpose of this study is to determine whether human dendritic cells(DCs) pulsed with glioma apoptotic bodies(GABs) can induce tumor-specific T lymphocytes having cytotoxicities to allogeneic glioma cells matched or mismatched at class I human leukocyte antigen(HLA) loci. Methods:DCs were generated from peripheral blood mononuclear cells(PBMCs) of HLA-A2 positive healthy donors cultured in the presence of granulocyte macrophage-colony stimulating factor and interleukin(IL)-4. GABs from HLAA2 positive T98G glioblastoma cells following actinomycin D treatment were pulsed to DCs. CD8+ T lymphocytes isolated from PBMCs of the same donors were cultured in media containing IL-2 and were stimulated by GAB-pulsed DCs three times at weekly interval. Then cytolytic activities of these cytotoxic CD8+ T cells against HLA-A2 positive T98G and U87 glioblastoma cells, and HLA-A2 negative A172 glioblastoma cells were determined by a standard 4hr [51Cr]-release assay. Results:The average percentages of T98G , U87 and A172 cell lysis were 43.7%, 45.6% and 5.1% compared with 3.6% of controls at an effector to target cell ratio of 40:1 respectively. The cytotoxic T lymphocytes(CTLs) primed with HLAA2 positive T98G GAB-pulsed DCs had cytotoxicity to HLA-A2 positive T98G and U87 glioma cells but not to HLAA2 negative A172 cells(p<0.01). Conclusion:This study showed that tumor-specific CTLs generated by stimulations with GAB-pulsed DCs had cytotoxicity to the glioma cells in a HLA-restricted manner. This result suggests the feasibility of the use of HLA-matched allogeneic glioma cells as a source of antigens for patients not eligible for surgery in the DC-based immunotherapy.