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      • SCOPUSKCI등재

        반복적인 급성 폐부종으로 나타난 신동맥 협착의 내과적 치험

        한선숙 ( Han Seon Sug ),최대희 ( Choe Dae Hui ),이성원 ( Lee Seong Won ),이희영 ( Lee Hui Yeong ),김우진 ( Kim U Jin ),이상현 ( Lee Sang Hyeon ),정해혁 ( Jeong Hae Hyeog ) 대한신장학회 2003 Kidney Research and Clinical Practice Vol.22 No.4

        Renal artery stenosis is a rare cause of acute pulmonary edema. So-called flash pulmonary edema is associated with bilateral renal artery stenosis or stenosis in a single functioning kidney. Most patients have co-morbid cardiovascular disease and a renovascular etiology is overlooked. Flash pulmonary edema has been recognized as an absolute indication for vascular intervention. However, our case could be treated with medical treatment directiong a complete inhibition of renin-angiotensin system. A 81-year old man was admitted with acute shortness of breath. During that admission, despite the dialysis therapy for renal insufficiency, he had four severe episodes of acute pulmonary edema requiring mechanical ventilation. CT angiography showed bilateral renal artery stenosis. After administration of ACE inhibitor, angiotensin receptor blocker, and spironolactone, there was no further attack of pulmonary edema. (Korean J Nephrol 2003;22(4):474-478)

      • SCOPUSKCI등재

        유지 혈액투석 환자에서 관상동맥 석회화와 C-반응단백 및 감염질환 항체가와의 상관관계

        최대희 ( Choe Dae Hui ),한선숙 ( Han Seon Sug ),이성원 ( Lee Seong Won ),이희영 ( Lee Hui Yeong ),정해혁 ( Jeong Hae Hyeog ),이승준 ( Lee Seung Jun ),이상현 ( Lee Sang Hyeon ),한헌 ( Han Heon ) 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.2

        목 적 : 말기신부전 환자에서 심혈관계 질환의 유병률과 그로 인한 사망률은 매우 높으나 그 원인 인자에 대해서는 명확히 밝혀져 있지 않다. 최근 고전적 위험인자 외에 염증반응이나 만성감염성 질환이 심혈관계 질환 발생에 관여함을 시사하는 연구 결과들이 나오고 있다. 저자들은 말기신부전 환자에서 관상동맥 질환의 발생을 관상동맥 석회화 수치 (coronary artery calcification score, CACs)를 측정하여 알아보고 이들 새로운 위험인자들과의 관련성을 밝혀보고자 하였다. 방 법 : 강원대학교병원에서 유지 혈액투석 중인 33명의 환자 (남:여=23:10, 연령=57±12세)를 대상으로 단면적 연구를 시행하였다. Multirow spiral CT (MSCT)를 이용하여 면적과 부피를 기준으로 CACs를 측정하였고, 염증반응의 지표로서 high sensitivi쇼 C-반응단백 (hs-CRP)과 IL-6를 측정하였으며, C. pneumoniae의 IgA 및 IgG 항체가와 H. pylori, cytomegalovirus, herpes simplex 등의 IgG 항체가를 측정하여 다음과 같은 결과를 얻었다. 결 과 : MSCT로 측정한 CACs는 중앙값 (범위)이 면적:379 (0-3662), 부피:338 (0-2,968)이었고, 면적 및 부피에서 100 이상의 높은 수치를 보인 경우는 각각 24명으로 73%에서 관찰되었다. Log (hs-CRP)와 log (CACs)는 상관관계 (면적:r=0.37, p<0.05, 부피:r=0.39, p<0.05)를 보였으나 log (IL-6)는 log (CACs)와 유의한 상관관계를 보이지 않았다. C. pneumoniae IgA와 IgG 양성률 (>1:64)은 각각 35%와 97%였고, C. pneumoniae의 IgA 및 IgG 항체가는 CACs와 유의한 관련성이 없었으며, H. pylori, cytomegalovirus IgG, herpes simplex 등의 IgG 항체가도 CACs와 관련성이 없었다. 환자의 연령과 log(CACs)는 양의 상관관계 (면적:r=0.39, p<0.05, 부피:r=0.39, p<0.05)를 보였으나, 당뇨유무, 흡력, 투석기간, 신체질량지수, 혈압, 혈중 cholesterol, albumin, PTH, calcium, phosphorous 등은 CACs와 유의한 관련성이 없었다. 결 론 : 혈액투석 중인 말기피신부전 환자에서 관상동맥의 심한 석회화를 흔하게 관찰할 수 있었고, 염증지표인 hs-CRP가 관상동맥 석회화와 관련이 있었다. C. pneumoniae 등 만성감염성 질환들의 항체가는 관상동맥 석회화와 유의한 관련성을 보이지 않았으나, 향후 보다 많은 환자를 대상으로 전향적인 연구가 필요할 것으로 생각된다. Background : Cardiovascular mortality is high in patients with end-stage renal disease (ESRD). Although the factors contributing to ESRD-related vascular disease are incompletely understood, recent studies suggest that inflammatory reaction or chronic infectious disease may play an important role as new risk factors. The aim of present study was to measure coronary artery caleification score (CACs) and to investigate the association with various markers of systemic inflammatory reaction. Methods : We conducted a cross-sectional study in 33 ptients (M : F=23:10, age=57±12 years) on maintenance hemodialysis. Multirow spiral CT (MSCT) was performed in all patients to measure CACs utilizing area and volume calculations. We measured high sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) as indicators of inflammatory reaction, and measured IgA and IgG antibodies to C. pneumoniae, and IgG antibodies to H. pylori, cytomegalovirus, and herpes simplex. Results : Median CACs equaled 379 (range, 0-3,662) by area and 338(range, 0-2,968) by volume. CACs more than 100 was present in 24 (73%) patients. Log (hs-CRP) was positively correlated with log (CACs) (area : r=0.37, p<0.05, volume : r=0.39, p<0.05), but log (IL-6) was not. There was no significant relationship between CACs and antibody titers to C. pneumoniae, H. pylori, cytomegalovirus, and herpes simplex. Age was positively correlated with log (CACs) (area : r=0.39, p<0.05, volume : r=0.39, p<0.05), but the presence of diabetes, smoking history, the duration of dialysis, body mass index, blood pressure, and serum cholesterol, albumin, PTH, calcium, and phosphorous levels were not. Conclusion : Coronary artery calcification was common in ESRD patients on hemodialysis, and associated with increased hs-CRP, an indicator of the presence of inflammatory reaction. There was no significant relationship between antibodies to chronic infections such as C. pneumoniae, but large-scale longitudinal studies are needed to evaluate fully that. (Korean J Nephrol 2004;23(2):278-286)

      • KCI등재

        현대무용전공자의 정서체험과 라이프스타일의 관계

        배소심(Bae So Sim),한선숙(Han Seon Sug) 한국여성체육학회 2003 한국여성체육학회지 Vol.17 No.2

        The object of this study was to identify the relationship between the emotional experience and the life style of modern dancers. The target population was composed of college students and directors of modern dance in the metropolitan area, and a total number of people were selected as the study group. For the survey, two types of questionnaires were used. One is based on Plummer(1971)`s which was modified by Sibeom Park(1993) and CheolHee Lee(1995). Another is based on SeonHye Ko`s(2000) which was modified according to comments given by experts in the area, and it was used for the life analysis. The study was carried out by visiting and distributing questionnaires in the target area. The surveyors explained the object of the study and the method of filling out the questionnaires to the participants and let them fill out the questionnaires at their own free will. The results were collected and analyzed during which unanswered questions were excluded, and the results were confirmed by using multiple regression with Windows SPSS/PC+8.0. Conclusions are as follows : First, the length of the period in which the participant has been practicing modern dance was found to be in proportion to the degree of free emotions experienced by the participant. In other words, the longer the participant has been practicing modern dance, the greer the spirit. Second, the intensity of the degree in which the participant has been practicing modern dance was found to be in proportion th the degree of conservatism in the participant`s lifestyle. In other words, the stronger the dancer`s participating intensity, the more conservative the life style. Third, the emotional energy the dancer experiences affects the degree of general dissatisfaction felt by the dancer as well as the degree in which the dancer participates in a cultural activity. As the dancers go through more new experiences, the life style of the advanced traditionalism, the dissatisfaction, and the expressive fashion are affected. And as the dancers experience suppression, the life style of the advanced accomplishment, the dissatisfaction and the cultural activity are affected.

      • SCOPUSKCI등재

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