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Intensity Modulated Radiotherapy 및 Cyberknife 치료 증례 동시 항암 화학-방사선 요법 후 근치적 간절제술을 시행한 제4기 간세포암종
김도영 ( D. Y. Kim ),한광협 ( K. H. Han ),성진실 ( J. S. Sung ),안상훈 ( S. H. Ahn ),김경식 ( K. S. Kim ),문창모 ( C. M. Moon ),김경규 ( K. K. Kim ),박영년 ( Y. N. Park ),전재윤 ( C. Y. Chon ),문영명 ( Y. M. Moon ) 대한간암학회 2005 대한간암학회지 Vol.5 No.-
혈중 및 간내 HBV 특이 CD8+ 세포의 Chemokine 수용체 발현
이천균 ( C. K. Lee ),정재연 ( J. Y. Chung ),서정훈 ( J. H. Suh ),조용석 ( Y. S. Cho ),한광협 ( K. H. Han ),정재복 ( J. B. Chung ),전재윤 ( C. Y. Chon ),문영명 ( Y. M. Moon ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<Background and Aim> The protective role of HBV-specific CD8+ cells is dependent on their ability to efficiently migrated to the infected liver, where they may exert effector function. The migratory behaviour and cytokine production of CD8+ cells is influ
간장 및 담도 : 간농양 치유 후 추적 영상진단상 이상 소견을 나타내는 간농양의 조직병리학적소견
이동기(D . K . Lee),김원호(W . H . Kim),한광협(K . H . Han),최흥재(H . J . Choi),박찬일(C .I . Park) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.1
N/A Medical therapy is standard for intrahepatic abscess and generally effective, but frequently radiologically abnormal lesion persist for long time followed by ultrasonography(US) or abnormal C-T, even after successful medical treatment including aspiration and complete clinical recovery. To access the histologic features of medically healed abscess but not disappeared completely in follow-up US or ahdominal C-T we performed liver biopsies in 5 cases of healed liver abscesses. The biopsy specimens were obtained at the margin of the lesions by cutting needle with ultrasono- graphic guiding. The biopsies were performed one time in one patient at variable period after treatment, 4 weeks in 2 cases, 6, 12 weeks & 17 months in each one case. The lobular architecture of the liver was relatively well preserved except the 2 specimens obtained at 4 weeks after treatment. And the specimens within 2 months showed hemorrhagic features rather than inflammatory, such as central hemorrhagic necrosis with extravasation of RBC. The sinusaidal system was dilated slightly. Some fibrosis involving portal tract and parenchyme of the liver was noted in the specimen of 6 weeks and 12 weeks. The specimen obtained at 17 months after treatment showed nearly normal liver architecture except minimal infiltration of lymphocyte in portal tract and parenchyme. Therefore, we concluded that in completely healed liver abscess, enen if abnormal reaiologic lesion persist for long time, the histologic feature of the lesion showed some hemorrhagic necrosis and infiltration of chronic inflammatory cells.
한국인에서 B형간염의 임상경과와 HLA DRB1*13 및 TNF - α promoter 유전자 다형성과의 상관관계에 대한 고찰
정재연 ( J. Y. Cheong ),한광협 ( K. H. Han ),송건훈 ( K. H. Song ),신전수 ( J. S. Shin ),장혜영 ( H. Y. Chang ),전은현 ( E. H. Chun ),이관식 ( K. S. Lee ),전재윤 ( C. Y. Chon ),문영명 ( Y. M. Moon ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> B형간염은 감염후에 다양한 임상경과를 갖는데 MHC classⅡ 대립유전자인 HLA-DRB1*1302가 바이러스 제거에 관여함이 제기되었고, 본교실에서는 1272명의 분석을 통해 HLA-DR13과 HBV의 제거와의 상관관계를 보고하였다. 본연구는 B형간염의 임상경과와 HLA-DR 및 TNF-α promoter 유전자 다형성과의 상관성을 알아보고자 하였다. <대상 및 방법> 1999년 1월부터 2001년 8월까지 세브란스병원에 내원한 176명을