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- 저자 : 한경도 ( Kyungdo Han ) (검색결과 4 건)
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여성 방광암 발생 위험 인자로서의 대사 건강 상태에 관한 연구: 우리나라 여성의 국민건강보험공단 국가 건강검진 자료 활용
한다은(Da Eun Han),안순태(Sun Tae Ahn),김종욱(Jong Wook Kim),오미미(Mi Mi Oh),문두건(Du Geon Moon),한경도(Kyungdo Han),박홍석(Hong Seok Park) 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.4
Purpose: This study investigated metabolic health status as a risk factor for female bladder cancer using the National Health Checkups databases of Korea. Materials and Methods: We defined obesity if body mass index was ≥25 kg/m² and normal weight as <25 kg/m². Metabolic unhealthiness was defined when 3 or more criteria of metabolic syndrome were met. A total of 11,461,618 women who took National health Checkups between 2009 and 2012 were categorized as metabolic healthy normal weight (MHNW), metabolic unhealthy normal weight (MuHNW), metabolic health obese (MHO), and metabolic unhealthy obese (MuHO). Multivariable-adjusted Cox regression was done to analyze the hazard ratio of bladder cancer. Results: The mean age was 48±11.55 years and body mass index was 23.19±2.13 kg/m². During 5.4±1.1 years of follow-up, 3,893 patients were newly diagnosed with bladder cancer. Compared to MHNW group, the hazard ratio of MuHNW group and MuHO group were 1.237 and 1.288, respectively, while 0.997 in the MHO group. As the number of metabolic unhealthy criteria increased, the cumulative incidence of bladder cancer increased. Conclusions: As a result of a large-scale study conducted on the female population in Korea, the risk of bladder cancer increased with metabolic unhealthiness. Even with normal weight, if metabolically unhealthy, the risk of bladder cancer increased. The greater the degree of metabolic unhealthiness, the higher the risk of bladder cancer. Education on metabolic healthiness concerning female bladder cancer is necessary.
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중증도 평가점수를 이용한 급성 세기관지염의 입원 기간 영향 요인 연구
정영상 ( Yeongsang Jeong ),황지현 ( Ji Hyen Hwang ),권지윤 ( Ji Yoon Kwon ),신정희 ( Jeonghee Shin ),권정현 ( Jung Hyun Kwon ),한경도 ( Kyungdo Han ),서원희 ( Won Hee Seo ),정지태 ( Ji Tae Choung ) 대한천식알레르기학회(구 대한알레르기학회) 2016 Allergy Asthma & Respiratory Disease Vol.4 No.6
Purpose: This study aimed to evaluate the clinical factors that could influence the length of hospital stay (LHS) of infants with acute bronchiolitis using the bronchiolitis severity score (BSS). Methods: The medical records of 105 infants aged 0-12 months with acute bronchiolitis who were admitted to a tertiary hospital between December 2014 and May 2015 were reviewed. The BSS was composed 5 factors, namely general condition, wheezing, chest retraction, respiration rate, and peripheral oxygen saturation, which were evaluated at admission. In addition, the age of the infants, LHS, body weight, birth history, familial history, laboratory test result, chest X-ray, and treatment modalities were reviewed. Subjects were classified into 3 groups according to their BSS, and logistic regression analysis was used to identify the association of the BSS with longer LHS. Results: Among subjects, 62 were studied. Their mean LHS and age were 5.5±2.0 days and 3.9±2.7 months, respectively. Twelve in fants were classified as mild (20.3%), 43 as moderate (68.8%), and 7 as severe (10.9%). Venous blood gas pH value and white blood cell count were the best predictors of disease severity. The LHS was associated with the BSS, age, body weight and pCO2 by venous blood gas analysis (P<0.05). Conclusion: The LHS was associated with the BSS, age, body weight, and pCO2 by venous blood gas analysis at admission. The BSS could be a useful tool to predict disease severity and decide treatment strategies for infants with acute bronchiolitis who have no known risk factors. (Allergy Asthma Respir Dis 2016:4:429-435)
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제2형 당뇨병 환자에서 비만과 미세혈관 합병증 발생의 연관성 : KNHIS 2009-2012
이정민(Jungmin Lee),이진영(Jin Yeong Lee),김보경(Bo Kyung Kim),박상현(Sang Hyun Park),한경도(Kyungdo Han),송수정(Su Jeong Song) 대한안과학회 2021 대한안과학회지 Vol.62 No.4
목적: 한국인 제2형 당뇨병환자에서 비만이 대표적인 만성 미세혈관 합병증인 심한 당뇨망막병증과 만성 신부전의 발생 위험인자인지 알아보고자 하였다. 대상과 방법: 국민건강보험공단 데이터베이스를 활용하여 2009년 1월부터 2012년 12월까지 전체 건강검진 수검자 중 제2형 당뇨병을 진단받은 30세 이상 성인 2,524,431명에 대하여 후향적 공단 자료 분석을 시행하여 제2형 당뇨병 환자에서 실명 위험 당뇨망막병증 및 말기 신부전의 발생과 비만과 연관된 인자들 중 체질량지수와 허리둘레의 연관성을 분석하였다. 결과: 다변량 콕스 회귀분석을 사용하여 분석한 결과, 실명 위험 당뇨망막병증(vision threatening diabetic retinopathy)과 말기 신부전을 포함하는 미세혈관합병증의 발생 위험인자를 고려하였을 때, 체질량지수와 미세혈관합병증은 역선형 관계를 보이지만, 허리둘레가 클수록 미세혈관합병증의 발생 위험도가 증가하는 통계적으로 유의미한 연관성을 보였다(incidence rate ratio, 1.049/1.087/1.234; 95% confidence interval, 1.021-1.078/1.05-1.125/1.182-1.289). 결론: 제2형 당뇨병 환자에서 허리둘레가 클수록 미세혈관 합병증 발생 위험도가 증가되는 연관성을 확인할 수 있었다. 제2형 당뇨병환자에서 만성 미세혈관 합병증 발생 위험 평가를 위하여 현재 비만 척도로 사용 중인 체질량지수와 더불어 허리 둘레가 함께 사용되어야 할 것으로 사료된다. Purpose: To observe if obesity is a representative risk factor for vision-threatening proliferative diabetes retinopathy and end stage renal disease, which are major chronic microvascular complications in Korean Type 2 diabetes patients. Methods: A retrospective data analysis was conducted on 2,524,431 adults over the age of 30 years diagnosed with type 2 diabetes using the Korean National Health Insurance Service-Health Screening database from January 2009 to December 2012. The association of body mass index (BMI) and waist circumference with the occurrence of sight-threatening diabetic retinopathy and end-stage renal disease in type 2 diabetes mellitus patients were analyzed. Results: Multivariable Cox regression analysis was carried out on the potential risk factors related to microvascular complications, including vision-threatening diabetic retinopathy and end-stage renal disease. BMI and microvascular complications showed a reverse linear relationship, but a larger waist circumference was associated with a greater risk of microvascular complications (incidence rate ratio [IRR] = 1.049, 95% confidence interval [CI] = 1.021-1.078; IRR = 1.087, 95% CI = 1.05-1.125, and IRR = 1.234, 95% CI = 1.182-1.289) after adjusting other risk factors. Conclusions: In our study, the results showed that type 2 diabetic patients with a larger waist circumference were at greater risk for microvascular complications. Thus, in addition to the BMI, the waist circumference should be used as the obesity parameter in microvascular complication risk assessment among type 2 diabetic patients.
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