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      • 家免를 利用한 PYROST®(Porous Hydroxyapatite)의 骨再生에 關한 實驗的 硏究

        崔應鈺,金泰淵,丁銓殷 고려대학교 의과대학 1989 고려대 의대 잡지 Vol.26 No.1

        PYROST® is a biocompatible porous matrix implantable as a bone graft substitute. This biomaterial has been used in a variety of experimental settings over the past years and more recently has been used in clinical applications for the filling of bone defects. Its use in human may help to eleminate the morbidity of autogenous bone graft donor sites and resorption of autogenous bone graft. We studied the new bone regeneration within a PYROST® block which were placed end to end in a subperiosteal pocket on the nasal dorsum of 1.8-2.0 ㎏ New Zealand white rabbit. En block specimen were harvested at 4, 8 and 12 weeks post onlay. These were then decalclfied, imbedded and sectioned in the sagittal plane. For the confirmation of bone regeneration within a PYROST® we used weighing the PYROST and light microscope. point-counting technique and fluorescent microscope. The results obtained were summarized as follow: 1. There was no volume change of PYROST® 2. The activation of osteoblasts and bone matrix were found at 4 weeks and matrix of lamellar pattern was found 12 weeks post onlay. 3. The quantity of the regenerated new bone within a PYROST® was increased at 12 weeks(3.2±2.1%) than 4 weeks(1.5± 1.8%).

      • SCOPUSKCI등재

        이소성 골형성에 의한 이개경화 2례의 임상적 고찰

        이종현,김종철,박정준,최응옥 大韓成形外科學會 1989 Archives of Plastic Surgery Vol.16 No.6

        Althrough auricle is an organ of hearing mechanism, it is playing on important role on one's appearance. Auricles are easily vulnerable to trauma because they are positioned on both estreme lateral aspect of face. Repeated severe trauma and stimulus on auricle bring on auricular petrification and eventually marked auricular deformity. These auricular deformities caused by petrified auricle have three kinds of characteristic; ectopic ossification, ectopic calcification, exostoses of exter nal auditory canal. Among them, petrified auricle by ectopic ossification has a stony hard consistency and is clinically a rare disease. We present, among ten cauliflower ears, two cases histologically proved partial ectopic ossification.

      • SCOPUSKCI등재

        가토를 이용한 PYROST(Porous Hydroxyapatite)의 골 재생에 관한 실험적 연구

        최응옥,정전은,최정호,김태연 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.3

        PYROST is a biocompatible porous matrix implantable as a bone graft substitute. This biomaterial has been used in a bariety of experimental settings over the past years and more recently has been used in clinical applications for the filling of bone defects. its use in human may help to eleminate the morbidity the morbidity of autogenous bone graft donor sites and resorption of autogenous bone graft. We studied the new bone regeneration within a PYROST block which were placed end to end in a subperiosteal pocket on the nasal dorsum of 1.8-2.0 kg New Zealand white rabbit. En block specimen were harvested at 4.8 and 12 weeks post onlay. These were then decalcified. imbedded and sectioned in the sagittal plane. For the confimation of bone regeneration within a PYROST we used weighing the PYROST and light microscope, point-counting technique and fluorescent microscope. The results obtained were summarized as follow : 1. There was no volume change of PYROST 2. The activation of osteoblasts and bone matrix were found of 4 weeks and matrix of lamellar pattern was found 12 weeks post onlay. 3. The quantity of the regenerated new bone within a PYROST was increased at 12 weeks (32 ±2.1%) than 4 weeks(15 ±1.8%).

      • SCOPUSKCI등재

        피하성회화결절(Subepidermal Calcified Nodule) 및 음낭부 특발성 석회증(Idiopathic Calcinosis of Scrotum)에 대한 임상 및 병리학적 고찰

        崔應鈺,丁銓殷,洪聖鎬 大韓成形外科學會 1983 Archives of Plastic Surgery Vol.10 No.3

        Subepidermal calcified nodule and idiopathic calcinosis of scrotum are subdivisions of the calcinosis cutis which calcium salt is deposited abnormally in skin and subcutaneous layer. Author summarized the clinico-histopathological characteristics of 21 cases of subepidermal calcified nodule and 2 cases of idiopathic calcinosis of scrotum at Korea University Hospital from January, 1970 to February, 1982. The results were as follows: 1. Incidence was I case among the about 3,000 surgical specimens. 2. Range of age of subepidermal calcified nodule was 14 to 72 years old and idiopathic calcinosis of scrotum was 25 years old in all cases. 3. Subepidermal calcified nodule occured equally in both sexes. 4. Clinical duration of subepidermal calcified nodule was 4 months to 6 years and there was no co-relation between clinical duration and size of tumor. 5. The gluteal region was the most frequent location of subepidermal calcified nodule and it was found on the trunk, extremities and face in descending order. 6. Subepidermal calcified nodule was single nodule in all cases, but idiopathic calcinosis of scrotum revealed two nodules in 50%, and the size of tumor ranged from 0.2cm to 6.0cm in diameter, but the most tumors measured 1.0 to 2.0cm in diameter. 7. Histopathologically subepidermal calcified nodule was located in dermal layer mostly. 8. Calcification was noted in all cases and foreign body giant cell was noted in most. 9. There was no recurrence or malignant change with simple surgical excision in all cases.

      • SCOPUSKCI등재

        비만곡증에 있어 비중격 교정의 중요성 : STUDY THROUGH ENDOSCOPE-TECHNIQUE OF INTRANASAL SEPTUM 비강내 촬영술을 통한 연구

        안희창,최응옥,김동구,배경태 大韓成形外科學會 1988 Archives of Plastic Surgery Vol.15 No.4

        Nose is important hard-tissue structure forming facial contour. Especially nasal septum which serves as main sustenance of nose causes deformity with minor trauma easily. Without precise reconstruction immediately right after injury, it may result in not only respiratory difficulties and changes in nasal-sound forming but also cosmetic problem. Therefore it requires precise diagnosis and immediate correction of damaged structure through that diagnosis. So far we have had many problems such as recurrence of deviated nose and depression of nasal dorsal surface by performing nasal septum surgery without examining exact deformity state and site. Examining the deviated nose in this hospital, we used the bronchoendoscope that has strong point in comparatively easy-examining and exact diagnosing and confirming deformed site before operation by direct eye-contact and in leaving records as photocopies. We performed taking photographs of 15 patients' traumatic septal deformities and grasped exact deformed state of septum and intra-septal deformity and selected appropriate surgical method. Thus we could get satisfying results by performing septal deformity corrections in applying these methods.

      • SCOPUSKCI등재

        手術前 血管造影術이 微細血管 吻合에 미치는 影響에 關한 實驗的 硏究

        金雨慶,崔應鈺,丁銓殷 大韓成形外科學會 1984 Archives of Plastic Surgery Vol.11 No.2

        Preoperative angiography of donor and recipient vessels before free flap transfer is helpful in evaluation and planning the operation. However, use of this clinically useful method is still controversial because of the possible harmful effect on intima and thrombus formation. We designed an experimental study on the effect of preoperative angiography on microvascular anastomosis. Fifty Sprague-Dawley rats, weighing 250∼300gm, were divided into 5 groups. Group 1: Normal saline injention with immediate anastomosis Group 2: Contrast media injention without anastomosis Group 3: Contrast media injection with immediate anastomosis Group 4: Contrast media injection with 1wk. later anastomosis Group 5: Contrast media injection with 2wk. later anastomosis CONRAY was injected through abdominal aorta 1∼1.2ml respectively and femoral artery and vein were cut and reanastomosed under operating microscope. Four weeks later, reexploration was performed, and then patency rate and histologic change was observed. The result was summerized as followings: 1) There were no statistically significant different patency rates between each group. 2) In all groups, it revealed patent vessel lumen without loss of endothelial layer. And there was no erythrocyte aggregation, no platelet adhesion. With this findings, we can conclude that there was no significant harmful effect of preoperative angiography on microvascular anastomosis.

      • SCOPUSKCI등재

        전신마취제가 피판 생존에 미치는 효과에 대한 연구

        이종원,최응옥,홍성표,황오열 大韓成形外科學會 1987 Archives of Plastic Surgery Vol.14 No.2

        Tissue nutrition is directly related to the functional status of the microcirculation because it is only in the terminal circulatory bed that exchanges between blood and cells are effective. Anesthetic drugs are known to be associated with marked changes in microvascular functional activity and with important changes in the reactivity of microvessels to humoral stimulation. The microcirculatory status of skin exposed to anesthetic drug is modified through direct, nervous or humoral mechanism. Skin flap survival was observed on the experimentally made critical flap in the rat and the following results were obtained. 1. The survival rate in the ketamine and enflurane groups increased as compared to control group. 2. The survival rate in the ehter group was not different to control group. 3. The survival rate in the halothane group decreased significantly as compared to control group. Harmful effect of halothane on skin flap decreases blood flow in venule rather than arteriole and the accumulation of its metabloites within skin flap inhibits oxygen consumption and glycolysis. 4. In conclusion, when the survival of flap was questionable, general naesthesia with ketamine and enflurane may be more preferable than that with halothane.

      • SCOPUSKCI등재

        大腿筋膜張筋의 臨床的 利用度에 對한 解部學的 硏究

        洪聖鎬,丁銓殷,崔應鈺,金世泳 大韓成形外科學會 1981 Archives of Plastic Surgery Vol.8 No.2

        Plastic and reconstructive surgery is mainly found on the skill and techniques developed in the movenent of tissue to repair defects of the body surface. The increased knowledge of the cutaneous circulation of body and the location and pattern of blood supply to each muscle and also refinement in surgical techniques provided the basis of successful transfer of various skin, muscle and myocutaneous units as rotation, island and even free flap. Especially the myocutaneous flap are employed to solve a variety of reconstructive problems. The Tensor Fascia Lata myocutaneous flap can be used as rotation, island and even free flap to cover the defects of the abdominal wall, lower extremities and pelvis and for closure of various pressure sore. And that flap showed exceedingly reliability with constant vascular pedicle and it can be easily elevated in its subfascial plane. In this paper, anatomical studies of size of the flap, running patterns of the vascular pedicles, size of vessels, distribution of sensory and motor nerves and clinical uses of the Tensor Fascia Lata were studied with 30 observation of 15 cadaver dissection. The results are summarized as follows: 1) The true Tensor Fascia Lata muscle length is 14cm in average from anterior superior iliac spine and it occupies proximal one third of lateral thigh. 2) The length between anterior superior iliac spine and great ertrochanter is 11.2cm which becomes the width of Tensor Fascia Lata flap. 3) The location of transverse branch of lateral femoral circumflex artery and vein are 7.2cm inferomedial to anterior superior iliac spine and also inferolateral to midinguinal point where femoral artery is located and the diameter of artery is 1.7mm and the diameter of venae comitantes accompanying to the entire course of the artery are 1.2mm in smaller vein, 2.6mm in larger one. 4) Transverse branch of lateral femoral circumflex artery is initially divided into two branches, then, from which another one is branched from initially branched superior or inferior branch so that three intramuscular branches present. 5) There are two sensory nerves; one is T 12 lateral femoral cutaneous nerve which occurs within 4.2cm posteriorly from anterior superior iliac spine. Another one is L 2.3 lateral femoral cutaneous nerve which occur within 2cm anteriorly from anterior superior iliac spine 6) According to the arterial course, there are one pair of venae comitantes constantly. 7) Lateral femoral circumflex artery is mainly branched from profunda femoris artery and lateral femoral circumflex vein is mainly drained into the femoral vein.

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