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      • 우리나라 성인에서 지질 수준과 우울증과의 관계 : 제4기 국민건강영양조사 자료 분석

        최세묵 충남대학교 대학원 2013 국내박사

        RANK : 247631

        This study is to analyze relationship between the level of lipids(Total cholesterol, Triglyceride, HDL-cholesterol, LDL-cholesterol) and depression in adults of Korea, as well as to research into its correlation with demographic, life style, physical, biochemical, hematologic, disease, taking medicine characteristics and depression. This study was conducted on 24,871 persons who participated in Korea National Health and Nutrition Examination Survey(KNHANES) (the 1st, 2nd and 3rd year at the 4th survey). Excluded insufficient data, in the end, the study was conducted on 7,341 men and 9,970 women aged 19 or older. The principal results are as in the following: 1. Prevalence of depression reaches 5.1% which is high in ≧70 of age group(8.1%) in women(6.8%) <100 million won(8.3%, monthly household income), previously married(10.0%), 1 person(9.6%, a member of household), below elementary school(8.8%), unemployed and non-economic activity population(7.6%, economic activity state), unpaid family worker(6.9%, work status), temporary employee(5.6%, employment types)(p<0.001)(Table 1). 2. Prevalence of depression by life style was significantly high in non-smoker(5.7%) none drinking(6.5%) non or irregular physical activity(5.6%). (Table 2). 3. Prevalence of depression by the disease and taking medicine was significantly high with hyperlipemia, stroke, cardiac infarction, heart attack and taking medicine for lowering cholesterol(p<0.05)(Table 3). 4. Mean±SD of depression by physical, blood pressure, laboratory, food intake characteristics of subjects was significantly low with weight, diastolic blood pressure, hemoglobin, daily food intake, daily energy intake and significantly high variables were found in systolic blood pressure, total cholesterol and LDL-cholesterol(p<0.05)(Table 4). 5. In terms of OR(95% CI) of depression by the level of lipids(adjusted for demographic, life style, physical, hematologic and diseases). OR of HDL-cholesterol was 1.563 in lower group compared with upper in women. OR of LDL-cholesterol was 5.327 in lower compared with upper in men(p<0.05)(Table 5). In conclusion, prevalence of depression in korean adults was 5.1%. Depression related with low LDL-cholesterol in adult men of Korea and OR was significantly high. Depression related with low HDL-cholesterol in adult women of Korea and OR was significantly high. These indicates that to lower severely cholesterol may cause other diseases. Thus, to prevent depression, cholesterol level should be in normal range.

      • 일개 대학병원 종합검진센터 수진자의 대사증후군 발생과 관련요인

        최세묵 충남대학교 보건대학원 2009 국내석사

        RANK : 247631

        The purpose of this research was to provide a guideline for precaution and management of cardiovascular disease. The methods taken in this research was to survey incidence and risk factors of the metabolic syndrome for Korean adult. This survey was conducted from January in 1997 to March in 2008. This study is a cohort study. The baseline subjects were 529 men and 609 women without metabolic syndrome(MS) who visited the health promotion center of Chungnam National University Hospital for general health check-up. The MS was diagnosed according to the definition by the National Cholesterol Education Program Adult Treatment Panel III. The abdominal obesity guidelines for waist circumference applied the Korean Society for the Study of Obesity Guideline. The survey exhibited that baseline risk factors that mainly affect odds ratio(OR) of the MS at follow-up were sex, ages, heavy drinking, uric acid and γ-glutamyl transpeptidase(GGT) in women. Incidence of the MS was 10.6% in total cases, 18.1% in case of the men and 4.0% in women. The risk of the MS was significantly lower in women than men(OR=0.4, 95% confidence interval(CI): 0.2∼0.9). 50∼59 Ages with OR of the MS showed significantly higher than < 40 ages(OR=3.4, 95% CI: 1.9∼6.4). The risk of the MS was significantly high in women with heavy drinkers(OR=14.3, 95% CI: 1.2∼177.5). The risk of the MS was significantly high in whole, men and women with high uric acid group(whole, OR=2.6, 95% CI: 1.6∼4.2. men, OR=2.1, 95% CI: 1.3∼3.5. women, OR=14.2, 95% CI: 3.0∼68.3). The risk of the MS was significantly high in women with high GGT(OR=1.8, 95% CI: 2.4∼12.6). These indicated that baseline sex, ages, heavy drinking in women, uric acid and GGT in women predicted incident MS. This survey can be utilized as an important index to determine risk factors of incident MS.

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