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        Barrett`s Esophagus 의 임상적 고찰

        이만호(M H Lee),이상종(S J Lee),김철우(C W kim),채종찬(J C Chae),박영철(Y C Park),정을순(E S Chung),김명숙(M.S. Kim) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2

        N/A Barrett's esophagus is a condition in which the normal stratified squamous mucosa of the esophagus is replaced by columnar mucosa, and it may be suspected on abnormal findings of endoscopy and the diagnosis is usually proved by biopsy. We have observed 10 cases suspecting with Barrett's esophagus on the endoscopic findings. Only 5 cases of them, however, could be proved as columnar epithelium-linked esophagus with histological examination. We observed for clinical features regarding age, sex, symptorns, habits, locations, combined diseases, and combined laboratory abnormalities for them. No significant differences of clinical features except serum lipid levels were seen between both groups of Barretts esophagus and chronic esophagitis. 1) All 5 patients with columnar epithelium-linked esophagus was male, and age distribution was from 35 to 60 with mean age of 50. 2) Number of the patients who complained reflux symptoms was 2 out of 5 patients. 3) There were 2 heavy alcohol consumers, 1 coffee drinkers, and 2 heavy cigarette smokers. 4) Location of the lesion was seen on upper esophagus in 3 cases, and on lower esophagus in 2 cases. 5) As a combined diseases, 2 cases with duodenal ulcer, 2 cases with fatty liver, one case with hepatitis, and one patient with rectal polyp. 6) In all 5 patients, serum cholesterol, serum triglyceride level, or both were elevated.

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