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폐결핵 환자에서의 발열의 빈도 및 화학치료에 대한 반응
인광호(Kwang Ho In),조재연(Jae Yon Cho),강경호(Kyung Ho Kang),유세화(Se Hwa Yoo) 대한내과학회 1991 대한내과학회지 Vol.40 No.2
N/A Fever is often used clinically to judge the severity of pulmonary tuberculosis and to evaluate its response to therapy. Sometimes fever persists for a long time even after starting chemotherapy. Records of 101 hospitalized patients with pulmonary tuberculosis were reviewed to investigate the incidence of fever, fever response to modern chemotherapy and analyzed possible factors affecting fever response in pulmonary tuberculosis. The results were as follows: 1) sixty-eight patients among 101 (69%) were febrile on admission. 2) There were no significant differences between febrile and afebrile groups in the extent of tuberculous lesion, presence of symptoms, and sputum smear positivity of acid-fast bacilli. 3) In febrile patients, the duration of fever after initiation of chemotherapy was short (mean, 5 days; range, 1 to 74 days). 4) In febrile patients there were no significant differences between early responders (<1 week) and the late responders (>1 week) in the extent of lesion, presence of symptoms, and smear positivity of acid-fast bacilli. In conclusion, the incidence of fever in pulmonary tuberculosis is high among admitted patients and fever subside after a few days of treatment in most cases, but sometimes it may persist much longer time.