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전신성홍반성 낭창 환자에서 면역억제제 사용중 발생한 재발성 대상포진
김태윤(Tae Yoon Kim),김진우(Jin Wou Kim),김형옥(Hyung Ok Kim),이강우(Kang Woo Lee),허원(Won Houh),조옥자(Ock Ja Cho),이승원(Seung Won Lee) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.1
Herpes zoster is known to be more frequent and severe in patients during immunosuppressive treatment and various predisposing factors, such as Hodgkin's disease, advanced tumor stage, local X-ray irradiation, splenectomy and cutaneous anergy. This report presents the case of a 23-year-old woman who developed herpes zoater on two separate occasione during the treatment of systemic lupus erythematosus with immunosuppressive agents (corticosteroid and cyclophosphamide). In each occasion, it was involved by different and multiple dermatomes. Treatment with oral and intralesional corticosteroids administration proved to be beneficial without any complication, although some delayed recovery of the disease was noted.
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선천성 백내장 및 가막백반을 동반한 저한성 외배엽 이형상의 1 예
이승원,조옥자 대한피부과학회 1981 大韓皮膚科學會誌 Vol.19 No.4
Hereditary hypohidrotic ectodermal dysplasia is a genodermatosis that demonstrates in its typical form a triad of hypohidrosis, hypotrichosis, and hypodontia Despite marked abnormalities of ectodermal structures, reports of cataract and corneal opacity have been conspicuously rare. This paper is a report of a case which shows the typical findings of HHED, congenital cataract, and corneal opacity.
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이강우,김진우,이승원,허원,김시용,조옥자 대한피부과학회 1982 대한피부과학회지 Vol.20 No.1
The purpose of this study was to elucidate the epidemiology and the clinical characteristics of herpes zoster and chicken pox. 703 patients with herpes zoster and 237 patients with chicken pox who were seen at the Department of Dermatology, St. Marys Hospital during 8 years were taken for this retrospective study. Both groups of the patients were evaluated in regard to annual, seasonal and monthly incidence, age incidence and sex ratio. Patients with herpes zoster were further assessed concerning associated conditions, dermatomic distributions and complications. The results were as follows, 1. The annual rate for chicken pox ranged from 0.03% to 0.18% (mean 0.13%) and revealed no epidemics, however, its incidence was higher in early summer and winter. There was no sexual difference. Chicken pox was seen most. frequently in the 0-9 year age group (91.1%). 2. The annual rate for herpes zoster ranged from 0.23% to 0.52% (mean 0.38%). There were no significant annual, seasonal and monthly variations, and there was a. equal sex ratio. Herpes zoster was seen most frequently in the 50-59 year age group (19.1%) 3. The frequencies of the associated conditions in herpes zoster, in descending order, were infectious disease (2. 7%), diabetes mellitus (2.3%), malignant neoplasm(1. 4%), immunosuppressive drug (l. 4%), autoimmune disease (0.6%), and radiation therapy (0.4%). 4. The dermatimie involvement of herps zoster was most frequent on thorcic dermatome(53.5%) and others were cervical(16.5%), lumber(10.1%), orphthalmic brance of trigeminal nerve(8.8%), sacral(1.6%), maxillary branch of trigeminla nerve(1.3%), mandibular brance of trigeminal nerve(0.6%) and facial nerve dermatome(0.1%). The incidence of involving two different dermatomes wasa 2.9% and was most common on cervicothoracic dermatome(1.8%). However, one case of cervico thoracic dermatome showed bilateral involvement. 5. The most common complication of herpes zoster was postherpetic neuralgia(6.5%) and others were secondary bacterial infection(2.6%), keratoconjunctivitis(0.6%), keloid formation(0.3%), generalized varicelliform eruption(0.1%), Ramsay-Hunt syndrome(0.1%) and recurrent herpes zoster(0.1%). The mean age of incidence of postherpetic neuralgia was 58.4 years and its indicence was the highest over 70 years(39.5%). Postherpetic peuralgia was most frequently seen in the involvement of ophthalmic branch of trigeminal nerve.
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