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한 가족에 발생한 Incontinentia Pigmenti 4 예
우태하,박욱화,조계은,오계익 대한피부과학회 1970 大韓皮膚科學會誌 Vol.8 No.2
Four cases of incontinentia pigmenti (Bloch-Sulzberger type) in a mother and three her daughter were presented and literatures were reviewed. In all three daughters vesicles appeared on toes at three weeks after birth and ehanged to pigmented patches surrounded by erythematous verrucous margin, which were then gradually spread to whole body. Pigmentation is dirty, irregular and bizarr. Severe itching sensation was complained and vesicles or bulla were formed easily due to scratching and external trauma. In mother, onset of the disease was not clear but generalized dirty pigmentation is showed. Dentition was delayed in 3rd daughter (Dental eruption was begun at 10 month old and 11 teeth was showed at now, 2 year old). Histopathological findings are compatible with incontinentia pigmenti and epidermo-dermaI separation is observed in a experimentally induced bullae, indicating a characterized epidermolysis bullosa. Strict limitation in the occurence of disease in females of one family, accompanying with epidermolysis bullosa simplex is unusual and interesting in genetical aspects and pathogenesis.
Cold Urticaria : ( Ice Cube Test and Treatment )
우태하,조정구,김영래,조계은 대한피부과학회 1970 大韓皮膚科學會誌 Vol.8 No.2
In an attempt to treat the cold urticaria, a new bradykinin inhibitor, homoclomin was administered orally and effective result were obtained. The urticaria was confirmed by the employing the ice cube test on the patient and the positive reaction was appeared generally 10 sec to 15 min after application of ice cube on the forearm. After oral administration for 3 days (40mg/day) clinical symptoms were relieved temporarily and weakly positive or negative reaction observed in repeated ice cube test.