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- 저자 : 정해권 ( Ha Gwon Juhng ) (검색결과 4 건)
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통풍과 동반된 칼슘피로인산 (Calcium Pyrophosphate Dihydrate) 결정침착 질환의
정해권 ( Ha Gwon Juhng ),이신석 ( Shin Seok Lee ),김윤아 ( Yun A Kim ) 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.2
Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease has various patterns of clinical manifestation ranging from an absence of symptoms to a severely destructive arthropathy. A number of metabolic diseases and physiologic stresses, such as aging and trauma, have been associated with CPPD crystal deposition. The coexistence of CPPD crystal deposition disease and gout varies from 2 to 8%. The mechanism of this association has been postulated to be a predisposition to the local deposition of pyrophosphate due to the presence of urate crystal, perhaps acting as a nucleating agent or factor which predispose to the deposition of both kinds of crystals. In Korea, although it is considered that CPPD crystal deposition occasionally coincides monosodium urate crystal, it has not been reported so far. We report a case with CPPD crystal deposition disease combined with gout in a patient who has suffered from osteoarthritis, which is diagnosed by polarized microscopic examination of synovial fluid.
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김윤아 ( Yun A Kim ),이신석 ( Shin Seok Lee ),정해권 ( Ha Gwon Juhng ) 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.1
Sjogren`s syndrome (SS) is a chronic, slowly progressive autoimmune disease characterized by lymphocytic infiltration of the exocrine glands leading to dry mouth and dry eyes accompanied by a variety of autoimmune phenomena. Despite the obvious difference in the affected organ, patients with SS and those with Hashimoto`s thyroiditis share several histologic and genetic features. The immunopathologic findings of Hashimoto`s thyroiditis and Sjogren`s sialadenitis show similarities such as infiltration by activated T lymphocytes and inappropriate expression of HLA class II molecules by the epithelial cells. It has been reported that up to 50% of patients with SS develop autoimmune thyroid disease in the clinical course, and patients with Hashimoto`s thyroiditis have symptoms related to SS frequently. In Korea, the ocurrence of SS in association with Hashimoto`s thyroiditis has not been reported so far, although it is considered to coexist occasionally. We report a case of primary SS in a patient with Hashimoto`s thyroiditis who had been treated with levothyroxine.
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Parvovirus B19에 의한 관절염 및 쇼그렌 항체 양성 발현
윤현정 ( Hyun Jung Yoon ),이신석 ( Shin Seok Lee ),정해권 ( Ha Gwon Juhng ) 대한류마티스학회 2005 대한류마티스학회지 Vol.12 No.1
Parvovirus B19 has been recently identified as the cause of various diseases such as erythema infectiosum, transient aplastic crisis in patients with chronic hemolytic anemias, hydrops fetalis, bone marrow suppression in immunocompromised hosts, and lastly acute and chronic arthropathy mimicking rheumatoid arthritis (RA) and occasionally, systemic lupus erythematosus (SLE). We describe a female patient who presented with fever, chills, polyarthralgia, serologic and PCR evidence of presence of Parvovirus B19, and expression of antinuclear antibody, anti-Ro/SSA and anti-La/SSB. There has been no clinical findings suggestive or diagnostic of any diffuse connective tissue diseases in this patient. Although there has been reports of Parvovirus B19 infection mimicking RA and SLE with manifestations of various autoimmune antibodies including rheumatoid factor, antinuclear antibody, anti-dsDNA, antilymphocyte antibody, and antiphospholipid antibody, there has not been any report of anti-Ro/SSA and anti-La/SSB expression in the setting of parvoviral arthropathy and this is the first case report.
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김윤아 ( Yun A Kim ),이신석 ( Shin Seok Lee ),정해권 ( Ha Gwon Juhng ) 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.4
Several gastrointestinal complications have been reported in association with systemic lupus erythematosus (SLE), including mesenteric vasculitis, bowel perforation, gastric or duodenal ulcer, necrotizing enterocolitis, spontaneous peritonitis, pancreatitis, spontaneous rupture of the liver or spleen and hepatomegaly. Acute acalculous cholecystitis is a rare disease that occurs in only 5~10% of patients with acute cholecystitis, typically in seriously ill patients. Reports of gallbladder diseases in patients with SLE are very scarce. Only seven cases of SLE complicated with acalculous cholecystitis have been reported so far, but not in Korea. Six cases were treated surgically by cholecystectomy or cholecystostomy, and one case was treated without surgical intervention. We added a case in which acute acalculous cholecystitis accompanying SLE was treated successfully by corticosteroid without surgical intervention.
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