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이승희,정지희,조지희 이화여자대학교 의과대학 1986 梨花醫學誌 Vol.- No.18
The subject of this study was 174 patients who were admitted to Ewha Woman's University Hospital and diagnosed histologically as liver disease during the period of 5 years from 1980 to 1984. And the results were as follows: 1) The order of major diseases of liver biopsy was fatty change(19.0%), chronic active hepatitis(17.3%), cirrhosis(16.1%), chronic persistent hepatitis(9.8%). 2) Serum total protein level was within the normal limits(6.5-7.9) in most liver diseases except amyloidosis (4.3gm/dl), necrosis & hematoma(4.6gm/dl), cholangiocarcinoma(5.8gm/dl), and the serum globulin level was high in all liver diseases. 3) The value of serum total bilirubin was elevated in most liver diseases except amyloidosis, tuberculosis, fatty change. 4) Striking elevation of serum alkaline phosphatase level was observed in cholangiocarcinoma, and abnormal serum level was observed in most liver diseases. 5) The serum ALT level of acute viral hepatitis, chronic active hepatitis, chronic persistent hepatitis, fatty change, hepatocellular carcinoma, metastatic carcinoma was abnormal. 6) Abnormal serum AST level was observed in most liver diseases except tuberculosis. 7) The highest positivity of HBsAg was observed in chronic active hepatitis, (96.0%), and the highest positivity of HBsAb was observed in fatty change (71.4%). 8) All the HBc Ab were positive in tested serum of acute viral hepatitis, chronic active hepatitis, hepatocellular carcinoma. 9) The highest positivity of HBeAg was obtained in chronic active hepatitis, (78.9%), and the highest positivity of HBeAb was obtained in chronic persistent hepatitis(58.3%). 10) Both IgM-Anti HBc and IgM-Anti HBV negative sera were observed in all tested.