http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 정장균(Jung, Jang-Gyun) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
-
정장균 대한동의병리학회 1995 동의생리병리학회지 Vol.9 No.2
연구배경 : 疎風ㆍ順氣ㆍ活血ㆍ祛痰 의 效能이 있어 中風 初期에 優先的으로 應用될 수 있는 處方임을 착안하여 高脂血症 外에 心血管系에 미치는 影響을 實驗的으로 糾明하고자 함. 방법 : 自發性 高血壓白鼠의 血壓變化, 家兎 의 耳殼血管灌流量의 變化, norepin-ephrine으로 誘導한 白鼠의 血管收縮變化, serotonin과 collagen으로 血栓性塞栓症을 誘發시킨 mouse의 死亡率變化, rat의 血小析凝集抑制 및 血凝凝固因子活性을 硏究 觀察함. 결과 : 血壓을 有意性있게 降下시키고, 家兎의 耳殼血管灌流量을 增加시켰으며, norepinephrine으로 誘導한 白鼠의 血管 收縮을 緩和시켰다. Mouse의 死亡率을 抑制시켰으며 rat의 血小析凝集을 有意性있게 抑制시켰으며 prothrombin time과 activated partial thromboplastin time을 延長시켰으나 有意性은 없었다. rat의 抗트롬빈活性을 나타냈으며 纖維素溶解時間을 有意性있게 短縮시켰고 纖維素溶解面積을 有意性있게 增加시켰다. 결론 : 疎風湯은 血管의 擴張에 의한 血流量增加 및 血壓의 下降을 나타내며 心血關系의 血液循環障碍를 改善시키고 혈전증 豫防하는데 사용할 수 있을 것으로 思料된다. The present experiment was desinged to investigate the effects of Sopung-tang water extracts on the Cardiovascular System in the Experimental Animals. Thus, the changes of blood pressure and heart rate were meas-ured after oral administration. Measurment of Mortality rate was observed for measuring the effect of Sopungtang water extract. Sopungtang water extract against pulmonary thrombo -embolism induced by collagen the mixture(0.1㎖/10g, 2㎎/㎏ B.W) plus serotonin(5㎎/㎏ B.W) in mouse. The effect of Sopungtang water extract was examined by observing the change of collagen-induced platelet aggregation, coagulation activity, exvivo and in vitro fibrinolytic activity of euglobulin fraction in rats. The results were summarized as followings. 1. Sopungtang dropped the blood pressure in spontaneous hypertensive rat. 2. The drug increased the auricular blood flow in rabbit. 3. The drug relaxed the artery contraction by pretreated norepinephrine in rat. 4. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 5. The drug ingihited the platelet aggregation in rat. 6. The drug prolonged the prothrombin time and activated partial thrombo-plastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 7. The drug increased the antithrombin activity in rat and the fibrinogen lyses time was reduced and lyses area was increased. 8. Sopungtang reduced fibrinogen lyses time of rat in vitro assay. According to the above mentioned results, Sopngtang increased the blood flow and dropped the blood pressure by the dilation of blood vessel. And the drug presented the antithrombin acivity, inhibited the platelet aggregation.
DBpia
DBpia연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
