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- 저자 : 정세규 ( Sekyoo Jeong ) (검색결과 4 건)
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보습제와 피부 지질 -피부 지질을 중심으로 본 보습제의 기능
정세규 ( Sekyoo Jeong ) 한국피부장벽학회 2015 한국피부장벽학회지 Vol.17 No.2
Along with the epidermal lipids and sebaceous gland-secreted lipids, exogenous lipids originated from topical products, pollution, and microbial metabolism, also importantly comprise the skin surface lipids. As one of the most commonly applied products on the skin, moisturizers can affect various features of skin lipids, including physical properties and biological activities. Emulsion formulation contains mainly water, lipids, emulsifiers, and other ingredients such as bioactive materials. In this talk, the effects of each component on the skin lipids will be briefly discussed.
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Cosmetics as A Defender for Skin Barrier Function
( Juyeon Jung ),정세규 ( Sekyoo Jeong ) 한국피부장벽학회 2020 한국피부장벽학회지 Vol.22 No.1
As the front line of protecting the human body against outer environment, stratum corneum (SC) is relentlessly attacked by the external stressors. Along with natural stressors, such as low humidity, abrupt temperature change, and sunlight, various artificial stressors also impact the skin barrier function. While the cosmetics are one of the most common “stressors” possibly disrupting epidermal permeability barrier function, potential beneficial effects of cosmetics on skin barrier function are also repeatedly reported. Supplementation of SC intercellular lipids with barrier creams, which show either compositional or structural similarity to those of SC lipids, can accelerate the recovery of damaged barrier functions. Bioactive ingredients stimulating the epidermal sphingolipids synthesis can also improve the skin barrier functions. Anti-oxidants and anti-inflammatory molecules, either directly or indirectly, protect skin barrier function against external stressors. In this review, protecting effects of cosmetics on skin barrier function and their possible defending mechanisms will be briefly discussed. An ideal combination of “barrier cosmetics” will be also suggested.
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Measurement of Skin Hydration Using IoT Devices
( Jongmi Lim ),( Heyjin Song ),( Changhee Han ),정세규 ( Sekyoo Jeong ) 한국피부장벽학회 2016 한국피부장벽학회지 Vol.18 No.1
Non-invasive measurement of skin functions, such as epidermal permeability barrier function, skin hydration and skin surface pH, generally requires specialized apparatus and controlled environmental conditions (i.e., temperature and relative humidity). While these data can provide invaluable information about the skin functions, they can only represent skin functions under specific experimental conditions. In order to analyze the changes of skin functions according to the practical environmental changes, such as by seasonal change or air pollution status, large number of data sets over a long-term measurement period are required. Considering the price and measurement protocols, classical measurement apparatuses are not practically applicable for these kinds of studies. Recent advances in IoT (internet of things) technology and sensor technology have made it possible for developing various kinds of wearable devices, which can track and record enormous number of data sets from human behaviors. Recently, we developed a portable device that measures the skin hydration and stores the data using IoT technology. Hypothetically, it can provide enough data sets which make it available to analyze the overall tendency of skin functions. While there are clear limits of these approaches, such as uncontrolled measurement conditions and non-standardized measurement protocols, big data analysis may overcome these limitations. In this talk, results of preliminary study will be discussed and further study plans with the device will suggested.
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