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2018 대한부정맥학회 심방세동 환자에서 NOAC 사용 지침: 출혈의 대처와 수술 전후 복약관리
이지현 ( Ji Hyun Lee ),임홍의 ( Hong Euy Lim ),임우현 ( Woo-hyun Lim ),안진희 ( Jinhee Ahn ),차명진 ( Myung-jin Cha ),박준범 ( Junbeom Park ),이기홍 ( Ki Hong Lee ),박환철 ( Hwan-cheol Park ),최의근 ( Eue-keun Choi ),정보영 ( Boyo 대한내과학회 2019 대한내과학회지 Vol.94 No.1
Although non-vitamin K-antagonist oral anticoagulants (NOACs) reduce major bleeding events in patients with atrial fibrillation more effectively than does warfarin, a significant bleeding risk remains. Patients exhibiting current bleeding and those who are expected to bleed require appropriate management, because NOAC discontinuation may increase the thromboembolic risk. This article details general management principles for patients experiencing current bleeding and those undergoing invasive surgery while on NOACs. (Korean J Med 2019;94:40-56)