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소세포폐암에서 항암화학요법 중 발생한 치명적 종양용해증후군
국은희 ( Eun Hee Kook ),김민수 ( Min Soo Kim ),안세한 ( Se Han Ahn ),전세용 ( Se Young Jeon ),윤정호 ( Jung Ho Yoon ),한민성 ( Min Sung Han ),김철현 ( Cheol Hyeon Kim ),이재철 ( Jae Cheol Lee ) 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.64 No.3
Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor. (Tuberc Respir Dis 2008;64:215-218)