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칼슘 길항제가 흰쥐의 위산 분비 및 혈청 Gastrin 에 미치는 영향
김종숙(Chong Sook Kim),박실무(Sill Moo Park),윤준현(Joon Hyun Yoon),김호빈(Ho Bin Kim),장세경(Sae Kyng Chang) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.2
N/A The effect of verapamil on gastric acid secretion and serum gastrin in the pylorus ligated rats was studied. The results were as follows; 1) The volume of gastric juice was increased in the verapamil-histamine group than in the histamine group. 2) The gastric acid output was decreased in the verapamil group and verapamil-histamine group than in the histamine group. 3) There was no statistical significance in serum gastrin concentration among each groups. Calcium-channel blocking agent inhibits the histamine-stimulated gastric acid secretion and dose not contribute on the serum gastrin concentration.