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        유리체강내 트리암시놀론 주입술 후 예방적 안압하강제의 효과

        이명원,경성은,장무환.Myung-Won Lee. M.D.. Sung Eun Kyung. M.D.. Moo-Hwan Chang. M.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.5

        Purpose: The purpose of this study was to investigate the prophylactic effect of brimonidine 0.15% on intraocular pressure (IOP) elevation and the risk factors for its elevation after intravitreal triamcinolone acetonide injection (IVTA). Methods: A prospective, randomized clinical trial was conducted on 67 eyes of 64 patients undergoing IVTA. Eyes were randomly divided into two groups, those which had used brimonidine 0.15% (40 eyes) and those which had not used it (27 eyes). IOP was measured preoperatively, at one week, and monthly until six months post-injection in each group. Results: The mean post‐injection IOP at one week was 11.93±3.36 mmHg for the group that had used brimonidine and 13.58±3.25 mmHg for the group that had not used it. The difference between the two groups was statistically significant at one week (p=0.049), but others were not statistically significant. An elevation in the IOP of more than 22 mmHg was seen in 8 eyes (20%) in the group using brimonidine and in 7 eyes (25.9%) in the group not using brimonidine. There was no difference in the incidence of IOP elevation between the two groups. Conclusions: Prophylactic use of brimonidine 0.15% will prevent sudden IOP elevation and will, therefore, prevent damage to the retina and optic nerve. However, in the long term, there is no prophylactic effect of brimonidine 0.15% on IOP elevation because there was no difference in the incidence of IOP elevation of more than 22 mmHg between the two groups.

      • KCI등재

        무한성 외배엽 이형성증 환자의 안과적 소견

        이명원,이동초,장무환.Myung Won Lee. M.D.. Dong Cho Lee. M.D.. Moo Hwan Chang. M.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.7

        Purpose: This clinical report describes the characteristics and ophthalmic treatment of a patient with anhidrotic ectodermal dysplasia showing bilateral upper eyelid entropion, conjunctival mass and dry eye syndrome. Methods: A 12-year-old boy presented to our clinic complaining of a white mass on the lower tarsal conjunctiva, foreign body sensation, and an itching in his right eye of one-year duration. He had developmental defects in his hair, teeth, nails and sweat glands. He had dry skin, a flat upper-lip, heat intolerance, a saddle-backed nose, and hypohidrosis. Ophthalmic examination showed blepharitis, a conjunctival mass, and bilateral upper eyelid entropion. Results: Upper eyelid entropion surgery was performed. An excisional biopsy of the conjunctival mass showed nonspecific acute and chronic inflammation. Conclusions: We concluded that the conjunctival mass developed as a result of chronic inflammation caused by chronic conjunctivitis and dry eye syndrome. Regular lid-hygiene with swab and lubrication is useful to minimize recurrent ocular inflammation in anhidrotic ectodermal dysplasia.

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        정상인에서 근시가 시야검사에 미치는 영향

        신용균,이명원,조경진,장무환,Yong Kyun Shin,MD,Myung Won Lee,MD,Kyoung Jin Cho,MD,PhD,Moo Hwan Chang,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.9

        Purpose: To investigate the effect of lens-corrected myopia on Humphrey Matrix and Humphrey Field Analyser (HFA). Methods: A total of 59 lens-corrected myopic eyes of 59 normal volunteers underwent Humphrey Field Analyser and Humphrey Matrix (FDP) testing. Spherical equivalent divided into 3 groups: -3 ≤ D < 0, -6 ≤ D < -3, D < -6. HFA and FDP sensitivity for mean deviation (MD) and pattern standard deviation (PSD), as well as axial length and astigmatism, were compared between these 3 groups. Results: The MD of the fields as determined by the HFA decreased significantly as the refractive errors increased, despite correction. However, there were no significant differences in MD or PSD of FDP, or in the PSD of HFA. There were no significant differences in axial length or astigmatism as calculated by MD and PSD for HFA and FDP. Conclusions: The spherical equivalent showed that lens correction alters the MD for HFA but not for FDP.J Korean Ophthalmol Soc 2014;55(9):1355-1360

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