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조진희 ( Jin Hee Cho ),유수경 ( Su Kyong Yu ),박정일 ( Jung Il Park ),이명희 ( Myoung Hee Lee ),임남규 ( Nam Kyu Lymm ),박인휘 ( In Whee Park ),김흥수 ( Heung Soo Kim ),임현이 ( Hyun Ee Yim ),신규태 ( Gyu Tae Shin ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.2
IgA nephropathy is the most common primary glomerulonephritis and characterized by deposition of IgA in glomerular mesangial area. Chronic urate nephropathy is characterized by precipitation of uric acid crystals in the collecting ducts and medullary interstitium. We report a case of IgA nephropathy associated with chronic urate nephropathy. A 57 year old man underwent percutaneous renal biopsy for gross hematuria, generalized edema and renal failure. Renal biopsy showed typical findings of IgA nephropathy: increased mesangial matrix, cellular proliferation and positive staining of IgA. In addition, crystalline deposits of uric acid, which is typical of chronic urate nephropathy, were seen in the medullary interstitium.